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Hippocampal contribution to early and later stages of implicit motor sequence learning

(2010) EXPERIMENTAL BRAIN RESEARCH. 202(4). p.795-807
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Abstract
Implicit motor sequence learning refers to an important human ability to acquire new motor skills through the repeated performance of a motor sequence. This learning process is characterized by slow, incremental gains of motor performance. The present fMRI study was developed to better delineate the areas supporting these temporal dynamics of learning. By using the serial color matching paradigm, our study focused on the motor level of sequence learning and tracked the time course of learning-related neural changes. Imaging results showed a significant contribution of the left anterior hippocampus in an early sequence acquisition stage (first scanning session) as well as during a later stage with stabilized learning effects (second scanning session). Hippocampal activation significantly correlated with the behavioral learning process and was affected by a change of the motor sequence. These results suggest a strong involvement of the hippocampus in implicit motor sequence learning. On the other hand, a very extensive and bilateral neural network of parietal, temporal and frontal cortical areas (including SMA, pre-SMA) together with parts of the cerebellum and striatum were found to play a role during random visuo-motor task performance.
Keywords
Hippocampus, Motor learning, Serial reaction time task, fMRI, PROCESS DISSOCIATION PROCEDURE, MEDIAL TEMPORAL-LOBE, REACTION-TIME-TASK, PERFORMANCE-MEASURES, BRAIN SYSTEMS, BASAL GANGLIA, MEMORY, FMRI, ACTIVATION, AMNESIA, Implicit sequence learning

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Citation

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MLA
Gheysen, Freja, Filip Van Opstal, Chantal Roggeman, et al. “Hippocampal Contribution to Early and Later Stages of Implicit Motor Sequence Learning.” EXPERIMENTAL BRAIN RESEARCH 202.4 (2010): 795–807. Print.
APA
Gheysen, F., Van Opstal, F., Roggeman, C., Van Waelvelde, H., & Fias, W. (2010). Hippocampal contribution to early and later stages of implicit motor sequence learning. EXPERIMENTAL BRAIN RESEARCH, 202(4), 795–807.
Chicago author-date
Gheysen, Freja, Filip Van Opstal, Chantal Roggeman, Hilde Van Waelvelde, and Wim Fias. 2010. “Hippocampal Contribution to Early and Later Stages of Implicit Motor Sequence Learning.” Experimental Brain Research 202 (4): 795–807.
Chicago author-date (all authors)
Gheysen, Freja, Filip Van Opstal, Chantal Roggeman, Hilde Van Waelvelde, and Wim Fias. 2010. “Hippocampal Contribution to Early and Later Stages of Implicit Motor Sequence Learning.” Experimental Brain Research 202 (4): 795–807.
Vancouver
1.
Gheysen F, Van Opstal F, Roggeman C, Van Waelvelde H, Fias W. Hippocampal contribution to early and later stages of implicit motor sequence learning. EXPERIMENTAL BRAIN RESEARCH. 2010;202(4):795–807.
IEEE
[1]
F. Gheysen, F. Van Opstal, C. Roggeman, H. Van Waelvelde, and W. Fias, “Hippocampal contribution to early and later stages of implicit motor sequence learning,” EXPERIMENTAL BRAIN RESEARCH, vol. 202, no. 4, pp. 795–807, 2010.
@article{1095455,
  abstract     = {Implicit motor sequence learning refers to an important human ability to acquire new motor skills through the repeated performance of a motor sequence. This learning process is characterized by slow, incremental gains of motor performance. The present fMRI study was developed to better delineate the areas supporting these temporal dynamics of learning. By using the serial color matching paradigm, our study focused on the motor level of sequence learning and tracked the time course of learning-related neural changes. Imaging results showed a significant contribution of the left anterior hippocampus in an early sequence acquisition stage (first scanning session) as well as during a later stage with stabilized learning effects (second scanning session). Hippocampal activation significantly correlated with the behavioral learning process and was affected by a change of the motor sequence. These results suggest a strong involvement of the hippocampus in implicit motor sequence learning. On the other hand, a very extensive and bilateral neural network of parietal, temporal and frontal cortical areas (including SMA, pre-SMA) together with parts of the cerebellum and striatum were found to play a role during random visuo-motor task performance.},
  author       = {Gheysen, Freja and Van Opstal, Filip and Roggeman, Chantal and Van Waelvelde, Hilde and Fias, Wim},
  issn         = {0014-4819},
  journal      = {EXPERIMENTAL BRAIN RESEARCH},
  keywords     = {Hippocampus,Motor learning,Serial reaction time task,fMRI,PROCESS DISSOCIATION PROCEDURE,MEDIAL TEMPORAL-LOBE,REACTION-TIME-TASK,PERFORMANCE-MEASURES,BRAIN SYSTEMS,BASAL GANGLIA,MEMORY,FMRI,ACTIVATION,AMNESIA,Implicit sequence learning},
  language     = {eng},
  number       = {4},
  pages        = {795--807},
  title        = {Hippocampal contribution to early and later stages of implicit motor sequence learning},
  url          = {http://dx.doi.org/10.1007/s00221-010-2186-6},
  volume       = {202},
  year         = {2010},
}

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