Ghent University Academic Bibliography

Advanced

Voice characteristics in adults with neurofibromatosis type 1

Marjan Cosyns UGent, Geert Mortier UGent, Paul Corthals UGent, Sandra Janssens UGent and John Van Borsel UGent (2011) JOURNAL OF VOICE. 25(6). p.759-764
abstract
Neurofibromatosis type 1 (NF1) is an autosomal dominant neurocutaneous disorder caused by mutations in the NF1 gene, which is located at the long arm of chromosome 17. Major characteristics include multiple cafe-au-lait spots and neurofibromas. Voice abnormalities have been reported to occur in this patient group. However, most studies relied on subjective measurements only. The present study reports the results of an objective voice assessment based on a multiparameter approach in 22 adults with NF1. Aerodynamic measurements, voice range profiles, acoustic voice quality and intonation measurements, and dysphonia severity indices were obtained and compared with data from a control group, consisting of 22 healthy adults. It was found that NF1 patients show a poorer overall voice quality compared with controls. Particularly, a reduction of vital capacity and limitations in laryngeal possibilities with respect to frequency and intensity were observed in the NF1 group.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
Acoustic analysis, Neurofibromatosis type 1, Dysphonia severity index., Voice, Voice range profile, Aerodynamic measurement, LARYNGEAL NEUROFIBROMA, PLEXIFORM NEUROFIBROMA, SPEECH, PREVALENCE, MANAGEMENT, DISORDERS, CHILDREN
journal title
JOURNAL OF VOICE
J. Voice
volume
25
issue
6
pages
759 - 764
Web of Science type
Article
Web of Science id
000297279100016
JCR category
OTORHINOLARYNGOLOGY
JCR impact factor
1.39 (2011)
JCR rank
15/41 (2011)
JCR quartile
2 (2011)
ISSN
0892-1997
DOI
10.1016/j.jvoice.2010.07.007
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1072534
handle
http://hdl.handle.net/1854/LU-1072534
date created
2010-11-09 17:52:27
date last changed
2012-01-30 10:27:58
@article{1072534,
  abstract     = {Neurofibromatosis type 1 (NF1) is an autosomal dominant neurocutaneous disorder caused by mutations in the NF1 gene, which is located at the long arm of chromosome 17. Major characteristics include multiple cafe-au-lait spots and neurofibromas. Voice abnormalities have been reported to occur in this patient group. However, most studies relied on subjective measurements only. The present study reports the results of an objective voice assessment based on a multiparameter approach in 22 adults with NF1. Aerodynamic measurements, voice range profiles, acoustic voice quality and intonation measurements, and dysphonia severity indices were obtained and compared with data from a control group, consisting of 22 healthy adults. It was found that NF1 patients show a poorer overall voice quality compared with controls. Particularly, a reduction of vital capacity and limitations in laryngeal possibilities with respect to frequency and intensity were observed in the NF1 group.},
  author       = {Cosyns, Marjan and Mortier, Geert and Corthals, Paul and Janssens, Sandra and Van Borsel, John},
  issn         = {0892-1997},
  journal      = {JOURNAL OF VOICE},
  keyword      = {Acoustic analysis,Neurofibromatosis type 1,Dysphonia severity index.,Voice,Voice range profile,Aerodynamic measurement,LARYNGEAL NEUROFIBROMA,PLEXIFORM NEUROFIBROMA,SPEECH,PREVALENCE,MANAGEMENT,DISORDERS,CHILDREN},
  language     = {eng},
  number       = {6},
  pages        = {759--764},
  title        = {Voice characteristics in adults with neurofibromatosis type 1},
  url          = {http://dx.doi.org/10.1016/j.jvoice.2010.07.007},
  volume       = {25},
  year         = {2011},
}

Chicago
Cosyns, Marjan, Geert Mortier, Paul Corthals, Sandra Janssens, and John Van Borsel. 2011. “Voice Characteristics in Adults with Neurofibromatosis Type 1.” Journal of Voice 25 (6): 759–764.
APA
Cosyns, Marjan, Mortier, G., Corthals, P., Janssens, S., & Van Borsel, J. (2011). Voice characteristics in adults with neurofibromatosis type 1. JOURNAL OF VOICE, 25(6), 759–764.
Vancouver
1.
Cosyns M, Mortier G, Corthals P, Janssens S, Van Borsel J. Voice characteristics in adults with neurofibromatosis type 1. JOURNAL OF VOICE. 2011;25(6):759–64.
MLA
Cosyns, Marjan, Geert Mortier, Paul Corthals, et al. “Voice Characteristics in Adults with Neurofibromatosis Type 1.” JOURNAL OF VOICE 25.6 (2011): 759–764. Print.