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A novel Aux/IAA28 signaling cascade activates GATA23-dependent specification of lateral root founder cell identity

Bert De Rybel UGent, Valya Vassileva UGent, Boris Parizot UGent, Marlies Demeulenaere UGent, Wim Grunewald UGent, Dominique Audenaert UGent, Jelle Van Campenhout UGent, Paul Overvoorde UGent, Leentje Jansen UGent and Steffen Vanneste UGent, et al. (2010) CURRENT BIOLOGY. 20(19). p.1697-1706
abstract
Background: Lateral roots are formed at regular intervals along the main root by recurrent specification of founder cells. To date, the mechanism by which branching of the root system is controlled and founder cells become specified remains unknown. Results: Our study reports the identification of the auxin regulatory components and their target gene, GATA23, which control lateral root founder cell specification. Initially, a meta-analysis of lateral root-related transcriptomic data identified the GATA23 transcription factor. GATA23 is expressed specifically in xylem pole pericycle cells before the first asymmetric division and is correlated with oscillating auxin signaling maxima in the basal meristem. Also, functional studies revealed that GATA23 controls lateral root founder cell identity. Finally, we show that an Aux/IAA28-dependent auxin signaling mechanism in the basal meristem controls GATA23 expression. Conclusions: We have identified the first molecular components that control lateral root founder cell identity in the Arabidopsis root. These include an IAA28-dependent auxin signaling module in the basal meristem region that regulates GATA23 expression and thereby lateral root founder cell specification and root branching patterns.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
OF-FUNCTION MUTATION, AUXIN TRANSPORT, INITIATION, FATE, GENE, EXPRESSION, DIFFERENTIATION, DIVISIONS, PERICYCLE, ARABIDOPSIS-THALIANA
journal title
CURRENT BIOLOGY
Curr. Biol.
volume
20
issue
19
pages
1697 - 1706
Web of Science type
Article
Web of Science id
000283041300021
JCR category
BIOCHEMISTRY & MOLECULAR BIOLOGY
JCR impact factor
10.025 (2010)
JCR rank
16/284 (2010)
JCR quartile
1 (2010)
ISSN
0960-9822
DOI
10.1016/j.cub.2010.09.007
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1070820
handle
http://hdl.handle.net/1854/LU-1070820
date created
2010-11-05 12:57:41
date last changed
2012-09-19 14:03:44
@article{1070820,
  abstract     = {Background: Lateral roots are formed at regular intervals along the main root by recurrent specification of founder cells. To date, the mechanism by which branching of the root system is controlled and founder cells become specified remains unknown.
Results: Our study reports the identification of the auxin regulatory components and their target gene, GATA23, which control lateral root founder cell specification. Initially, a meta-analysis of lateral root-related transcriptomic data identified the GATA23 transcription factor. GATA23 is expressed specifically in xylem pole pericycle cells before the first asymmetric division and is correlated with oscillating auxin signaling maxima in the basal meristem. Also, functional studies revealed that GATA23 controls lateral root founder cell identity. Finally, we show that an Aux/IAA28-dependent auxin signaling mechanism in the basal meristem controls GATA23 expression.
Conclusions: We have identified the first molecular components that control lateral root founder cell identity in the Arabidopsis root. These include an IAA28-dependent auxin signaling module in the basal meristem region that regulates GATA23 expression and thereby lateral root founder cell specification and root branching patterns.},
  author       = {De Rybel, Bert and Vassileva, Valya and Parizot, Boris and Demeulenaere, Marlies and Grunewald, Wim and Audenaert, Dominique and Van Campenhout, Jelle and Overvoorde, Paul and Jansen, Leentje and Vanneste, Steffen and M{\"o}ller, Barbara and Wilson, Michael and Holman, Tara and Van Isterdael, Gert and Brunoud, G{\'e}raldine and Vuylsteke, Marnik and Vernoux, Teva and De Veylder, Lieven and Inz{\'e}, Dirk and Weijers, Dolf and Bennett, Malcolm J and Beeckman, Tom},
  issn         = {0960-9822},
  journal      = {CURRENT BIOLOGY},
  keyword      = {OF-FUNCTION MUTATION,AUXIN TRANSPORT,INITIATION,FATE,GENE,EXPRESSION,DIFFERENTIATION,DIVISIONS,PERICYCLE,ARABIDOPSIS-THALIANA},
  language     = {eng},
  number       = {19},
  pages        = {1697--1706},
  title        = {A novel Aux/IAA28 signaling cascade activates GATA23-dependent specification of lateral root founder cell identity},
  url          = {http://dx.doi.org/10.1016/j.cub.2010.09.007},
  volume       = {20},
  year         = {2010},
}

Chicago
De Rybel, Bert, Valya Vassileva, Boris Parizot, Marlies Demeulenaere, Wim Grunewald, Dominique Audenaert, Jelle Van Campenhout, et al. 2010. “A Novel Aux/IAA28 Signaling Cascade Activates GATA23-dependent Specification of Lateral Root Founder Cell Identity.” Current Biology 20 (19): 1697–1706.
APA
De Rybel, B., Vassileva, V., Parizot, B., Demeulenaere, M., Grunewald, W., Audenaert, D., Van Campenhout, J., et al. (2010). A novel Aux/IAA28 signaling cascade activates GATA23-dependent specification of lateral root founder cell identity. CURRENT BIOLOGY, 20(19), 1697–1706.
Vancouver
1.
De Rybel B, Vassileva V, Parizot B, Demeulenaere M, Grunewald W, Audenaert D, et al. A novel Aux/IAA28 signaling cascade activates GATA23-dependent specification of lateral root founder cell identity. CURRENT BIOLOGY. 2010;20(19):1697–706.
MLA
De Rybel, Bert, Valya Vassileva, Boris Parizot, et al. “A Novel Aux/IAA28 Signaling Cascade Activates GATA23-dependent Specification of Lateral Root Founder Cell Identity.” CURRENT BIOLOGY 20.19 (2010): 1697–1706. Print.