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Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds

(2010) ADVANCED SYNTHESIS & CATALYSIS. 352(16). p.2751-2756
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Abstract
The deoxofluorination of cyclic a,a-dialkoxy ketones with morpholinosulfur trifluoride (Morph-DAST) resulted in 1,2-dialkoxy-1,2-difluorinated carbo- and heterocyclic compounds. The reaction proceeds via a 1,2-alkoxy migration leading to mixtures of cis- and trans-isomers.
Keywords
MEDICINAL CHEMISTRY, COUPLING-CONSTANTS, DIETHYLAMINOSULFUR TRIFLUORIDE, deoxofluorination, SUGARS, 2-ULOSES, GLUCOSE, fluorine, ketones, piperidines, rearrangement reactions, FLUORIDES, 3-DIFLUOROPIPERIDINES, 3, ALCOHOLS, DAST REAGENT

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Citation

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MLA
Surmont, Riccardo, et al. “Morpholinosulfur Trifluoride (Morph-DAST)-Mediated Rearrangement in the Fluorination of Cyclic α,α-Dialkoxy Detones toward 1,2-Dialkoxy-1,2-Difluorinated Compounds.” ADVANCED SYNTHESIS & CATALYSIS, vol. 352, no. 16, 2010, pp. 2751–56, doi:10.1002/adsc.201000466.
APA
Surmont, R., Verniest, G., De Groot, A., Thuring, J. W., & De Kimpe, N. (2010). Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds. ADVANCED SYNTHESIS & CATALYSIS, 352(16), 2751–2756. https://doi.org/10.1002/adsc.201000466
Chicago author-date
Surmont, Riccardo, Guido Verniest, Alex De Groot, Jan Willem Thuring, and Norbert De Kimpe. 2010. “Morpholinosulfur Trifluoride (Morph-DAST)-Mediated Rearrangement in the Fluorination of Cyclic α,α-Dialkoxy Detones toward 1,2-Dialkoxy-1,2-Difluorinated Compounds.” ADVANCED SYNTHESIS & CATALYSIS 352 (16): 2751–56. https://doi.org/10.1002/adsc.201000466.
Chicago author-date (all authors)
Surmont, Riccardo, Guido Verniest, Alex De Groot, Jan Willem Thuring, and Norbert De Kimpe. 2010. “Morpholinosulfur Trifluoride (Morph-DAST)-Mediated Rearrangement in the Fluorination of Cyclic α,α-Dialkoxy Detones toward 1,2-Dialkoxy-1,2-Difluorinated Compounds.” ADVANCED SYNTHESIS & CATALYSIS 352 (16): 2751–2756. doi:10.1002/adsc.201000466.
Vancouver
1.
Surmont R, Verniest G, De Groot A, Thuring JW, De Kimpe N. Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds. ADVANCED SYNTHESIS & CATALYSIS. 2010;352(16):2751–6.
IEEE
[1]
R. Surmont, G. Verniest, A. De Groot, J. W. Thuring, and N. De Kimpe, “Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds,” ADVANCED SYNTHESIS & CATALYSIS, vol. 352, no. 16, pp. 2751–2756, 2010.
@article{1069329,
  abstract     = {{The deoxofluorination of cyclic a,a-dialkoxy ketones with morpholinosulfur trifluoride (Morph-DAST) resulted in 1,2-dialkoxy-1,2-difluorinated carbo- and heterocyclic compounds. The reaction proceeds via a 1,2-alkoxy migration leading to mixtures of cis- and trans-isomers.}},
  author       = {{Surmont, Riccardo and Verniest, Guido and De Groot, Alex and Thuring, Jan Willem and De Kimpe, Norbert}},
  issn         = {{1615-4150}},
  journal      = {{ADVANCED SYNTHESIS & CATALYSIS}},
  keywords     = {{MEDICINAL CHEMISTRY,COUPLING-CONSTANTS,DIETHYLAMINOSULFUR TRIFLUORIDE,deoxofluorination,SUGARS,2-ULOSES,GLUCOSE,fluorine,ketones,piperidines,rearrangement reactions,FLUORIDES,3-DIFLUOROPIPERIDINES,3,ALCOHOLS,DAST REAGENT}},
  language     = {{eng}},
  number       = {{16}},
  pages        = {{2751--2756}},
  title        = {{Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds}},
  url          = {{http://dx.doi.org/10.1002/adsc.201000466}},
  volume       = {{352}},
  year         = {{2010}},
}

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