Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds
- Author
- Riccardo Surmont (UGent) , Guido Verniest (UGent) , Alex De Groot, Jan Willem Thuring and Norbert De Kimpe (UGent)
- Organization
- Abstract
- The deoxofluorination of cyclic a,a-dialkoxy ketones with morpholinosulfur trifluoride (Morph-DAST) resulted in 1,2-dialkoxy-1,2-difluorinated carbo- and heterocyclic compounds. The reaction proceeds via a 1,2-alkoxy migration leading to mixtures of cis- and trans-isomers.
- Keywords
- MEDICINAL CHEMISTRY, COUPLING-CONSTANTS, DIETHYLAMINOSULFUR TRIFLUORIDE, deoxofluorination, SUGARS, 2-ULOSES, GLUCOSE, fluorine, ketones, piperidines, rearrangement reactions, FLUORIDES, 3-DIFLUOROPIPERIDINES, 3, ALCOHOLS, DAST REAGENT
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-1069329
- MLA
- Surmont, Riccardo, Guido Verniest, Alex De Groot, et al. “Morpholinosulfur Trifluoride (Morph-DAST)-mediated Rearrangement in the Fluorination of Cyclic Α,α-dialkoxy Detones Toward 1,2-dialkoxy-1,2-difluorinated Compounds.” ADVANCED SYNTHESIS & CATALYSIS 352.16 (2010): 2751–2756. Print.
- APA
- Surmont, R., Verniest, G., De Groot, A., Thuring, J. W., & De Kimpe, N. (2010). Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds. ADVANCED SYNTHESIS & CATALYSIS, 352(16), 2751–2756.
- Chicago author-date
- Surmont, Riccardo, Guido Verniest, Alex De Groot, Jan Willem Thuring, and Norbert De Kimpe. 2010. “Morpholinosulfur Trifluoride (Morph-DAST)-mediated Rearrangement in the Fluorination of Cyclic Α,α-dialkoxy Detones Toward 1,2-dialkoxy-1,2-difluorinated Compounds.” Advanced Synthesis & Catalysis 352 (16): 2751–2756.
- Chicago author-date (all authors)
- Surmont, Riccardo, Guido Verniest, Alex De Groot, Jan Willem Thuring, and Norbert De Kimpe. 2010. “Morpholinosulfur Trifluoride (Morph-DAST)-mediated Rearrangement in the Fluorination of Cyclic Α,α-dialkoxy Detones Toward 1,2-dialkoxy-1,2-difluorinated Compounds.” Advanced Synthesis & Catalysis 352 (16): 2751–2756.
- Vancouver
- 1.Surmont R, Verniest G, De Groot A, Thuring JW, De Kimpe N. Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds. ADVANCED SYNTHESIS & CATALYSIS. 2010;352(16):2751–6.
- IEEE
- [1]R. Surmont, G. Verniest, A. De Groot, J. W. Thuring, and N. De Kimpe, “Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds,” ADVANCED SYNTHESIS & CATALYSIS, vol. 352, no. 16, pp. 2751–2756, 2010.
@article{1069329,
abstract = {The deoxofluorination of cyclic a,a-dialkoxy ketones with morpholinosulfur trifluoride (Morph-DAST) resulted in 1,2-dialkoxy-1,2-difluorinated carbo- and heterocyclic compounds. The reaction proceeds via a 1,2-alkoxy migration leading to mixtures of cis- and trans-isomers.},
author = {Surmont, Riccardo and Verniest, Guido and De Groot, Alex and Thuring, Jan Willem and De Kimpe, Norbert},
issn = {1615-4150},
journal = {ADVANCED SYNTHESIS & CATALYSIS},
keywords = {MEDICINAL CHEMISTRY,COUPLING-CONSTANTS,DIETHYLAMINOSULFUR TRIFLUORIDE,deoxofluorination,SUGARS,2-ULOSES,GLUCOSE,fluorine,ketones,piperidines,rearrangement reactions,FLUORIDES,3-DIFLUOROPIPERIDINES,3,ALCOHOLS,DAST REAGENT},
language = {eng},
number = {16},
pages = {2751--2756},
title = {Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds},
url = {http://dx.doi.org/10.1002/adsc.201000466},
volume = {352},
year = {2010},
}
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