Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds
- Author
- Riccardo Surmont (UGent) , Guido Verniest (UGent) , Alex De Groot, Jan Willem Thuring and Norbert De Kimpe (UGent)
- Organization
- Abstract
- The deoxofluorination of cyclic a,a-dialkoxy ketones with morpholinosulfur trifluoride (Morph-DAST) resulted in 1,2-dialkoxy-1,2-difluorinated carbo- and heterocyclic compounds. The reaction proceeds via a 1,2-alkoxy migration leading to mixtures of cis- and trans-isomers.
- Keywords
- MEDICINAL CHEMISTRY, COUPLING-CONSTANTS, DIETHYLAMINOSULFUR TRIFLUORIDE, deoxofluorination, SUGARS, 2-ULOSES, GLUCOSE, fluorine, ketones, piperidines, rearrangement reactions, FLUORIDES, 3-DIFLUOROPIPERIDINES, 3, ALCOHOLS, DAST REAGENT
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-1069329
- MLA
- Surmont, Riccardo, et al. “Morpholinosulfur Trifluoride (Morph-DAST)-Mediated Rearrangement in the Fluorination of Cyclic α,α-Dialkoxy Detones toward 1,2-Dialkoxy-1,2-Difluorinated Compounds.” ADVANCED SYNTHESIS & CATALYSIS, vol. 352, no. 16, 2010, pp. 2751–56, doi:10.1002/adsc.201000466.
- APA
- Surmont, R., Verniest, G., De Groot, A., Thuring, J. W., & De Kimpe, N. (2010). Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds. ADVANCED SYNTHESIS & CATALYSIS, 352(16), 2751–2756. https://doi.org/10.1002/adsc.201000466
- Chicago author-date
- Surmont, Riccardo, Guido Verniest, Alex De Groot, Jan Willem Thuring, and Norbert De Kimpe. 2010. “Morpholinosulfur Trifluoride (Morph-DAST)-Mediated Rearrangement in the Fluorination of Cyclic α,α-Dialkoxy Detones toward 1,2-Dialkoxy-1,2-Difluorinated Compounds.” ADVANCED SYNTHESIS & CATALYSIS 352 (16): 2751–56. https://doi.org/10.1002/adsc.201000466.
- Chicago author-date (all authors)
- Surmont, Riccardo, Guido Verniest, Alex De Groot, Jan Willem Thuring, and Norbert De Kimpe. 2010. “Morpholinosulfur Trifluoride (Morph-DAST)-Mediated Rearrangement in the Fluorination of Cyclic α,α-Dialkoxy Detones toward 1,2-Dialkoxy-1,2-Difluorinated Compounds.” ADVANCED SYNTHESIS & CATALYSIS 352 (16): 2751–2756. doi:10.1002/adsc.201000466.
- Vancouver
- 1.Surmont R, Verniest G, De Groot A, Thuring JW, De Kimpe N. Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds. ADVANCED SYNTHESIS & CATALYSIS. 2010;352(16):2751–6.
- IEEE
- [1]R. Surmont, G. Verniest, A. De Groot, J. W. Thuring, and N. De Kimpe, “Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds,” ADVANCED SYNTHESIS & CATALYSIS, vol. 352, no. 16, pp. 2751–2756, 2010.
@article{1069329,
abstract = {{The deoxofluorination of cyclic a,a-dialkoxy ketones with morpholinosulfur trifluoride (Morph-DAST) resulted in 1,2-dialkoxy-1,2-difluorinated carbo- and heterocyclic compounds. The reaction proceeds via a 1,2-alkoxy migration leading to mixtures of cis- and trans-isomers.}},
author = {{Surmont, Riccardo and Verniest, Guido and De Groot, Alex and Thuring, Jan Willem and De Kimpe, Norbert}},
issn = {{1615-4150}},
journal = {{ADVANCED SYNTHESIS & CATALYSIS}},
keywords = {{MEDICINAL CHEMISTRY,COUPLING-CONSTANTS,DIETHYLAMINOSULFUR TRIFLUORIDE,deoxofluorination,SUGARS,2-ULOSES,GLUCOSE,fluorine,ketones,piperidines,rearrangement reactions,FLUORIDES,3-DIFLUOROPIPERIDINES,3,ALCOHOLS,DAST REAGENT}},
language = {{eng}},
number = {{16}},
pages = {{2751--2756}},
title = {{Morpholinosulfur trifluoride (Morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy detones toward 1,2-dialkoxy-1,2-difluorinated compounds}},
url = {{http://dx.doi.org/10.1002/adsc.201000466}},
volume = {{352}},
year = {{2010}},
}
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