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Rationale and methods of the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA)

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Abstract
Background: The EURIKA study aims to assess the status of primary prevention of cardiovascular disease (CVD) across Europe. Specifically, it will determine the degree of control of cardiovascular risk factors in current clinical practice in relation to the European guidelines on cardiovascular prevention. It will also assess physicians' knowledge and attitudes about CVD prevention as well as the barriers impeding effective risk factor management in clinical practice. Methods/Design: Cross-sectional study conducted simultaneously in 12 countries across Europe. The study has two components: firstly at the physician level, assessing eight hundred and nine primary care and specialist physicians with a daily practice in CVD prevention. A physician specific questionnaire captures information regarding physician demographics, practice settings, cardiovascular prevention beliefs and management. Secondly at the patient level, including 7641 patients aged 50 years or older, free of clinical CVD and with at least one classical risk factor, enrolled by the participating physicians. A patient-specific questionnaire captures information from clinical records and patient interview regarding sociodemographic data, CVD risk factors, and current medications. Finally, each patient provides a fasting blood sample, which is sent to a central laboratory for measuring serum lipids, apolipoproteins, hemoglobin-A1c, and inflammatory biomarkers. Discussion: Primary prevention of CVD is an extremely important clinical issue, with preventable circulatory diseases remaining the leading cause of major disease burden. The EURIKA study will provide key information to assess effectiveness of and attitudes toward primary prevention of CVD in Europe. A transnational study creates opportunities for benchmarking good clinical practice across countries and improving outcomes. (ClinicalTrials.gov number, NCT00882336.)
Keywords
ICORONARY-HEART-DISEASE, PRIMARY-CARE PHYSICIANS, PROJECT, COUNTRIES, GUIDELINES, CLINICAL-PRACTICE, C-REACTIVE PROTEIN, EVENTS, IMPLEMENTATION, IMPROVEMENT

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Chicago
Rodriguez-Artalejo, Fernando, Eliseo Guallar, Claudio Borghi, Jean Dallongeville, Gui De Backer, Julian P Halcox, Ramón Hernández-Vecino, et al. 2010. “Rationale and Methods of the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA).” Bmc Public Health 10.
APA
Rodriguez-Artalejo, F., Guallar, E., Borghi, C., Dallongeville, J., De Backer, G., Halcox, J. P., Hernández-Vecino, R., et al. (2010). Rationale and methods of the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA). BMC PUBLIC HEALTH, 10.
Vancouver
1.
Rodriguez-Artalejo F, Guallar E, Borghi C, Dallongeville J, De Backer G, Halcox JP, et al. Rationale and methods of the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA). BMC PUBLIC HEALTH. 2010;10.
MLA
Rodriguez-Artalejo, Fernando, Eliseo Guallar, Claudio Borghi, et al. “Rationale and Methods of the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA).” BMC PUBLIC HEALTH 10 (2010): n. pag. Print.
@article{1067553,
  abstract     = {Background: The EURIKA study aims to assess the status of primary prevention of cardiovascular disease (CVD) across Europe. Specifically, it will determine the degree of control of cardiovascular risk factors in current clinical practice in relation to the European guidelines on cardiovascular prevention. It will also assess physicians' knowledge and attitudes about CVD prevention as well as the barriers impeding effective risk factor management in clinical practice.
Methods/Design: Cross-sectional study conducted simultaneously in 12 countries across Europe. The study has two components: firstly at the physician level, assessing eight hundred and nine primary care and specialist physicians with a daily practice in CVD prevention. A physician specific questionnaire captures information regarding physician demographics, practice settings, cardiovascular prevention beliefs and management. Secondly at the patient level, including 7641 patients aged 50 years or older, free of clinical CVD and with at least one classical risk factor, enrolled by the participating physicians. A patient-specific questionnaire captures information from clinical records and patient interview regarding sociodemographic data, CVD risk factors, and current medications. Finally, each patient provides a fasting blood sample, which is sent to a central laboratory for measuring serum lipids, apolipoproteins, hemoglobin-A1c, and inflammatory biomarkers.
Discussion: Primary prevention of CVD is an extremely important clinical issue, with preventable circulatory diseases remaining the leading cause of major disease burden. The EURIKA study will provide key information to assess effectiveness of and attitudes toward primary prevention of CVD in Europe. A transnational study creates opportunities for benchmarking good clinical practice across countries and improving outcomes. (ClinicalTrials.gov number, NCT00882336.)},
  articleno    = {382},
  author       = {Rodriguez-Artalejo, Fernando and Guallar, Eliseo and Borghi, Claudio and Dallongeville, Jean and De Backer, Gui and Halcox, Julian P and Hern{\'a}ndez-Vecino, Ram{\'o}n and Jim{\'e}nez, Francisco Javier and Mass{\'o}-Gonz{\'a}lez, Elvira L and Perk, Joep and Steg, Philippe Gabriel and Banegas, Jos{\'e} R},
  issn         = {1471-2458},
  journal      = {BMC PUBLIC HEALTH},
  keyword      = {ICORONARY-HEART-DISEASE,PRIMARY-CARE PHYSICIANS,PROJECT,COUNTRIES,GUIDELINES,CLINICAL-PRACTICE,C-REACTIVE PROTEIN,EVENTS,IMPLEMENTATION,IMPROVEMENT},
  language     = {eng},
  pages        = {9},
  title        = {Rationale and methods of the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA)},
  url          = {http://dx.doi.org/10.1186/1471-2458-10-382},
  volume       = {10},
  year         = {2010},
}

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