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Perceived stigma among patients receiving antiretroviral treatment: A prospective randomised trial comparing an m-DOT strategy with standard-of-care in Kenya

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Abstract
HIV and AIDS remain highly stigmatised. Modified directly observed therapy (m-DOT) supports antiretroviral treatment (ART) adherence but little is known about its association with perceived stigma in resource-constrained settings. In 2003, 234 HIV-infected adults enrolled in a two-arm randomised trial comparing a health centre-based m-DOT strategy with standard self-administration of ART. Data on perceived stigma were collected using Berger's HIV stigma scale prior to starting ART and after 12 months. This was a secondary analysis to examine whether perceived stigma was related to treatment delivery. Perceived stigma scores declined after 12 months of treatment from a mean of 44.9 (sd = 7.6) to a mean of 41.4 (sd = 7.7), (t = 6.14, P < 0.001). No differences were found between the mean scores of participants in both study arms. Also, no difference in scores was detected using GLM, controlling for socio-demographic characteristics and baseline scores. Findings indicate that a well managed clinic-based m-DOT does not increase perceived HIV-related stigma.
Keywords
attitudes, Africa, perceived stigma, HIV/AIDS, directly observed therapy, DIRECTLY OBSERVED THERAPY, HIV-RELATED STIGMA, SUB-SAHARAN AFRICA, INFECTED DRUG-USERS, IMPROVE ADHERENCE, MEDICATION ADHERENCE, INCREASE ADHERENCE, ART ADHERENCE, SOUTH-AFRICA, INTERVENTION

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Chicago
Kaai, Susan, Sandra Bullock, Avina Sarna, Matthew Chersich, Stanley Lüchters, Scott Geibel, Paul Munyao, Kishorchandra Mandaliya, Marleen Temmerman, and Naomi Rutenberg. 2010. “Perceived Stigma Among Patients Receiving Antiretroviral Treatment: A Prospective Randomised Trial Comparing an m-DOT Strategy with Standard-of-care in Kenya.” Sahara J-journal of Social Aspects of Hiv-aids 7 (2): 62–70.
APA
Kaai, S., Bullock, S., Sarna, A., Chersich, M., Lüchters, S., Geibel, S., Munyao, P., et al. (2010). Perceived stigma among patients receiving antiretroviral treatment: A prospective randomised trial comparing an m-DOT strategy with standard-of-care in Kenya. SAHARA J-JOURNAL OF SOCIAL ASPECTS OF HIV-AIDS, 7(2), 62–70.
Vancouver
1.
Kaai S, Bullock S, Sarna A, Chersich M, Lüchters S, Geibel S, et al. Perceived stigma among patients receiving antiretroviral treatment: A prospective randomised trial comparing an m-DOT strategy with standard-of-care in Kenya. SAHARA J-JOURNAL OF SOCIAL ASPECTS OF HIV-AIDS. CLAREMONT: SA MEDICAL ASSOC HEALTH & MEDICAL PUBL GROUP; 2010;7(2):62–70.
MLA
Kaai, Susan, Sandra Bullock, Avina Sarna, et al. “Perceived Stigma Among Patients Receiving Antiretroviral Treatment: A Prospective Randomised Trial Comparing an m-DOT Strategy with Standard-of-care in Kenya.” SAHARA J-JOURNAL OF SOCIAL ASPECTS OF HIV-AIDS 7.2 (2010): 62–70. Print.
@article{1040428,
  abstract     = {HIV and AIDS remain highly stigmatised. Modified directly observed therapy (m-DOT) supports antiretroviral treatment (ART) adherence but little is known about its association with perceived stigma in resource-constrained settings. In 2003, 234 HIV-infected adults enrolled in a two-arm randomised trial comparing a health centre-based m-DOT strategy with standard self-administration of ART. Data on perceived stigma were collected using Berger's HIV stigma scale prior to starting ART and after 12 months. This was a secondary analysis to examine whether perceived stigma was related to treatment delivery. Perceived stigma scores declined after 12 months of treatment from a mean of 44.9 (sd = 7.6) to a mean of 41.4 (sd = 7.7), (t = 6.14, P {\textlangle} 0.001). No differences were found between the mean scores of participants in both study arms. Also, no difference in scores was detected using GLM, controlling for socio-demographic characteristics and baseline scores. Findings indicate that a well managed clinic-based m-DOT does not increase perceived HIV-related stigma.},
  author       = {Kaai, Susan and Bullock, Sandra and Sarna, Avina and Chersich, Matthew and L{\"u}chters, Stanley and Geibel, Scott and Munyao, Paul and Mandaliya, Kishorchandra and Temmerman, Marleen and Rutenberg, Naomi},
  issn         = {1729-0376},
  journal      = {SAHARA J-JOURNAL OF SOCIAL ASPECTS OF HIV-AIDS},
  keyword      = {attitudes,Africa,perceived stigma,HIV/AIDS,directly observed therapy,DIRECTLY OBSERVED THERAPY,HIV-RELATED STIGMA,SUB-SAHARAN AFRICA,INFECTED DRUG-USERS,IMPROVE ADHERENCE,MEDICATION ADHERENCE,INCREASE ADHERENCE,ART ADHERENCE,SOUTH-AFRICA,INTERVENTION},
  language     = {eng},
  number       = {2},
  pages        = {62--70},
  publisher    = {SA MEDICAL ASSOC HEALTH \& MEDICAL PUBL GROUP},
  title        = {Perceived stigma among patients receiving antiretroviral treatment: A prospective randomised trial comparing an m-DOT strategy with standard-of-care in Kenya},
  url          = {http://www.sahara.org.za/index.php/SAHARA-J-Vol.-7-No.-2-August-2010/View-category.html},
  volume       = {7},
  year         = {2010},
}

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