Advanced search
1 file | 540.13 KB

Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage

(2010) JOURNAL OF GENERAL VIROLOGY. 91(7). p.1659-1667
Author
Organization
Abstract
Porcine reproductive and respiratory syndrome virus (PRRSV) emerged in the late 1980s and rapidly became one of the most significant viral pathogens in the swine industry. In vivo, the virus shows a very narrow cell tropism and targets specific subsets of porcine macrophages. The entry of PRRSV into its host cell is the first crucial step in infection and has been the focus of many fundamental studies. This review provides a comprehensive overview of the current knowledge on PRRSV entry into the porcine macrophage, covering virus binding, internalization and genome release, and integrates these findings into a general model of the entry process.
Keywords
STRUCTURAL PROTEIN, MOLECULAR ANALYSIS, DENDRITIC CELLS, SIALIC-ACID, LELYSTAD-VIRUS, ALVEOLAR MACROPHAGES, MYSTERY SWINE DISEASE, ACID-BINDING-SITE, ISOLATE ATCC VR-2332, SITE-DIRECTED MUTAGENESIS

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 540.13 KB

Citation

Please use this url to cite or link to this publication:

Chicago
Van Breedam, Wander, Peter Delputte, Hanne Van Gorp, Gerald Misinzo, Nathalie Vanderheijden, XiaoBo Duan, and Hans Nauwynck. 2010. “Porcine Reproductive and Respiratory Syndrome Virus Entry into the Porcine Macrophage.” Journal of General Virology 91 (7): 1659–1667.
APA
Van Breedam, W., Delputte, P., Van Gorp, H., Misinzo, G., Vanderheijden, N., Duan, X., & Nauwynck, H. (2010). Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage. JOURNAL OF GENERAL VIROLOGY, 91(7), 1659–1667.
Vancouver
1.
Van Breedam W, Delputte P, Van Gorp H, Misinzo G, Vanderheijden N, Duan X, et al. Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage. JOURNAL OF GENERAL VIROLOGY. 2010;91(7):1659–67.
MLA
Van Breedam, Wander, Peter Delputte, Hanne Van Gorp, et al. “Porcine Reproductive and Respiratory Syndrome Virus Entry into the Porcine Macrophage.” JOURNAL OF GENERAL VIROLOGY 91.7 (2010): 1659–1667. Print.
@article{1026247,
  abstract     = {Porcine reproductive and respiratory syndrome virus (PRRSV) emerged in the late 1980s and rapidly became one of the most significant viral pathogens in the swine industry. In vivo, the virus shows a very narrow cell tropism and targets specific subsets of porcine macrophages. The entry of PRRSV into its host cell is the first crucial step in infection and has been the focus of many fundamental studies. This review provides a comprehensive overview of the current knowledge on PRRSV entry into the porcine macrophage, covering virus binding, internalization and genome release, and integrates these findings into a general model of the entry process.},
  author       = {Van Breedam, Wander and Delputte, Peter and Van Gorp, Hanne and Misinzo, Gerald and Vanderheijden, Nathalie and Duan, XiaoBo and Nauwynck, Hans},
  issn         = {0022-1317},
  journal      = {JOURNAL OF GENERAL VIROLOGY},
  keywords     = {STRUCTURAL PROTEIN,MOLECULAR ANALYSIS,DENDRITIC CELLS,SIALIC-ACID,LELYSTAD-VIRUS,ALVEOLAR MACROPHAGES,MYSTERY SWINE DISEASE,ACID-BINDING-SITE,ISOLATE ATCC VR-2332,SITE-DIRECTED MUTAGENESIS},
  language     = {eng},
  number       = {7},
  pages        = {1659--1667},
  title        = {Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage},
  url          = {http://dx.doi.org/10.1099/vir.0.020503-0},
  volume       = {91},
  year         = {2010},
}

Altmetric
View in Altmetric
Web of Science
Times cited: