Opportunistic salpingectomy : is surgical completeness achieved? Insights from the QOS study
- Author
- Anne-Sophie Maryns, Tjalina Hamerlynck (UGent) , Charlotte Van Overberghe, Ellen Allaert, Julie Rombaut, Amber Lievens, Sabine Declercq, Amin Makar (UGent) , Wiebren Tjalma, Philippe Tummers (UGent) and Koen Van de Vijver (UGent)
- Organization
- Abstract
- Methods: Patients scheduled for gynaecological surgery involving unilateral or bilateral adnexectomy were prospectively enrolled in the Quality of Opportunistic Salpingectomy (QOS) study at two hospitals in Flanders. During the procedure, adnexectomy was performed in two steps: first salpingectomy, followed by oophorectomy. Pathologists examined the ovarian surface both macroscopically and microscopically to determine the presence of residual fimbrial tissue. For pathological analysis, the Sectioning and Extensively Examining the Fimbria (SEEFIM) protocol or a modified SEE-FIM protocol was used. The predefined sample size was 192 adnexa. Patient enrolment occurred between January 2023 and April 2025. Results: A total of 201 adnexa from 115 patients were analysed. Macroscopic fimbrial tissue on the ovarian cortex was suspected in six cases (2.7%), of which four were microscopically confirmed. Overall, residual microscopic fimbrial tissue was identified in 15 adnexa (7.4%) from 14 patients (12.2%). In one patient, both fallopian tubes were incompletely resected. No serous tubal intraepithelial carcinoma (STIC) lesions were detected. Conclusions: Opportunistic salpingectomy was surgically complete in almost nine out of ten patients. Residual fimbrial tissue could not be predicted by clinical or surgical factors, underscoring the importance of a meticulous surgical technique and standardized pathological assessment. The clinical impact of remnant fimbrial tissue on ovarian cancer risk reduction remains uncertain, particularly in the context of risk-reducing salpingectomy with delayed oophorectomy.
- Keywords
- Opportunistic salpingectomy, SEE-FIM protocol, Serous tubal intraepithelial carcinoma, STIC lesion, Primary prevention, Tubo-ovarian surface, OVARIAN-CANCER, FALLOPIAN-TUBE, RISK, MUTATION, ORIGIN, BREAST, WOMEN
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-01KN2397EG69V3404EED8H5ZDA
- MLA
- Maryns, Anne-Sophie, et al. “Opportunistic Salpingectomy : Is Surgical Completeness Achieved? Insights from the QOS Study.” EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, vol. 321, 2026, doi:10.1016/j.ejogrb.2026.115066.
- APA
- Maryns, A.-S., Hamerlynck, T., Van Overberghe, C., Allaert, E., Rombaut, J., Lievens, A., … Van de Vijver, K. (2026). Opportunistic salpingectomy : is surgical completeness achieved? Insights from the QOS study. EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 321. https://doi.org/10.1016/j.ejogrb.2026.115066
- Chicago author-date
- Maryns, Anne-Sophie, Tjalina Hamerlynck, Charlotte Van Overberghe, Ellen Allaert, Julie Rombaut, Amber Lievens, Sabine Declercq, et al. 2026. “Opportunistic Salpingectomy : Is Surgical Completeness Achieved? Insights from the QOS Study.” EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY 321. https://doi.org/10.1016/j.ejogrb.2026.115066.
- Chicago author-date (all authors)
- Maryns, Anne-Sophie, Tjalina Hamerlynck, Charlotte Van Overberghe, Ellen Allaert, Julie Rombaut, Amber Lievens, Sabine Declercq, Amin Makar, Wiebren Tjalma, Philippe Tummers, and Koen Van de Vijver. 2026. “Opportunistic Salpingectomy : Is Surgical Completeness Achieved? Insights from the QOS Study.” EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY 321. doi:10.1016/j.ejogrb.2026.115066.
- Vancouver
- 1.Maryns A-S, Hamerlynck T, Van Overberghe C, Allaert E, Rombaut J, Lievens A, et al. Opportunistic salpingectomy : is surgical completeness achieved? Insights from the QOS study. EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY. 2026;321.
- IEEE
- [1]A.-S. Maryns et al., “Opportunistic salpingectomy : is surgical completeness achieved? Insights from the QOS study,” EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, vol. 321, 2026.
@article{01KN2397EG69V3404EED8H5ZDA,
abstract = {{Methods: Patients scheduled for gynaecological surgery involving unilateral or bilateral adnexectomy were prospectively enrolled in the Quality of Opportunistic Salpingectomy (QOS) study at two hospitals in Flanders. During the procedure, adnexectomy was performed in two steps: first salpingectomy, followed by oophorectomy. Pathologists examined the ovarian surface both macroscopically and microscopically to determine the presence of residual fimbrial tissue. For pathological analysis, the Sectioning and Extensively Examining the Fimbria (SEEFIM) protocol or a modified SEE-FIM protocol was used. The predefined sample size was 192 adnexa. Patient enrolment occurred between January 2023 and April 2025. Results: A total of 201 adnexa from 115 patients were analysed. Macroscopic fimbrial tissue on the ovarian cortex was suspected in six cases (2.7%), of which four were microscopically confirmed. Overall, residual microscopic fimbrial tissue was identified in 15 adnexa (7.4%) from 14 patients (12.2%). In one patient, both fallopian tubes were incompletely resected. No serous tubal intraepithelial carcinoma (STIC) lesions were detected. Conclusions: Opportunistic salpingectomy was surgically complete in almost nine out of ten patients. Residual fimbrial tissue could not be predicted by clinical or surgical factors, underscoring the importance of a meticulous surgical technique and standardized pathological assessment. The clinical impact of remnant fimbrial tissue on ovarian cancer risk reduction remains uncertain, particularly in the context of risk-reducing salpingectomy with delayed oophorectomy.}},
articleno = {{115066}},
author = {{Maryns, Anne-Sophie and Hamerlynck, Tjalina and Van Overberghe, Charlotte and Allaert, Ellen and Rombaut, Julie and Lievens, Amber and Declercq, Sabine and Makar, Amin and Tjalma, Wiebren and Tummers, Philippe and Van de Vijver, Koen}},
issn = {{0301-2115}},
journal = {{EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY}},
keywords = {{Opportunistic salpingectomy,SEE-FIM protocol,Serous tubal intraepithelial carcinoma,STIC lesion,Primary prevention,Tubo-ovarian surface,OVARIAN-CANCER,FALLOPIAN-TUBE,RISK,MUTATION,ORIGIN,BREAST,WOMEN}},
language = {{eng}},
pages = {{7}},
title = {{Opportunistic salpingectomy : is surgical completeness achieved? Insights from the QOS study}},
url = {{http://doi.org/10.1016/j.ejogrb.2026.115066}},
volume = {{321}},
year = {{2026}},
}
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