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The active monitoring of oxytocin research evidence (AMORE) platform

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Abstract
Oxytocin, an evolutionarily conserved neuropeptide, plays a crucial role in various physiological and behavioural processes, offering potential therapeutic benefits for several psychiatric and neurodevelopmental conditions. Despite its promise, oxytocin research has been marked by inconsistent results concerning its therapeutic applications and underlying mechanisms. Performing a systematic review and meta-analysis is a popular approach to shed light on mixed findings in a body of literature; however, they can become quickly outdated as new evidence becomes available. Given these challenges, research on the links between oxytocin and biobehavioural outcomes is ideally positioned for the adoption of 'living' meta-analyses, which allow for the continuous integration of new data and updated conclusions. Here we introduce the Active Monitoring of Oxytocin Research Evidence (AMORE) platform (https://amore-project.org), which is a hub that aggregates articles and materials associated with living meta-analyses for biobehavioural oxytocin research in humans. Developed through consensus among 24 expert researchers, a standardized framework was established that either requires or recommends practices ensuring transparency and rigor in living meta-analyses featured on the AMORE platform. Overall, AMORE has been designed to advance human oxytocin biobehavioural research by the timely integration of emerging evidence through transparent living meta-analyses. To date, two living meta-analysis projects at different stages of publication are hosted on AMORE, demonstrating the platform's practical application.
Keywords
Living meta-analysis, Systematic Review, Evidence synthesis, Oxytocin, Transparency, RANDOMIZED CONTROLLED-TRIAL, INTRANASAL OXYTOCIN, SYSTEMATIC REVIEWS, DEPRESSIVE-DISORDERS, ENDOGENOUS OXYTOCIN, MATERNAL-BEHAVIOR, EXPOSURE THERAPY, SOCIAL COGNITION, RECEPTOR, INDIVIDUALS

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MLA
Iversen, IA, et al. “The Active Monitoring of Oxytocin Research Evidence (AMORE) Platform.” PSYCHONEUROENDOCRINOLOGY, vol. 185, 2026, doi:10.1016/j.psyneuen.2025.107713.
APA
Iversen, I., Alaerts, K., Bakermans-Kranenburg, M., Becker, B., Blair, R., Bartz, J., … Quintana, D. (2026). The active monitoring of oxytocin research evidence (AMORE) platform. PSYCHONEUROENDOCRINOLOGY, 185. https://doi.org/10.1016/j.psyneuen.2025.107713
Chicago author-date
Iversen, IA, K Alaerts, M Bakermans-Kranenburg, B Becker, RJ Blair, JA Bartz, JJ Connelly, et al. 2026. “The Active Monitoring of Oxytocin Research Evidence (AMORE) Platform.” PSYCHONEUROENDOCRINOLOGY 185. https://doi.org/10.1016/j.psyneuen.2025.107713.
Chicago author-date (all authors)
Iversen, IA, K Alaerts, M Bakermans-Kranenburg, B Becker, RJ Blair, JA Bartz, JJ Connelly, B Ditzen, NC Ebner, H Kang, EA Lawson, NN Lonfeldt, Matthijs Moerkerke, C Montag, A-RC Mora-Jensen, M Horta, L Peled-Avron, TL Procyshyn, AI Sartorius, D Scheele, E Schneider, C Theofanopoulou, H Yamasue, and DS Quintana. 2026. “The Active Monitoring of Oxytocin Research Evidence (AMORE) Platform.” PSYCHONEUROENDOCRINOLOGY 185. doi:10.1016/j.psyneuen.2025.107713.
Vancouver
1.
Iversen I, Alaerts K, Bakermans-Kranenburg M, Becker B, Blair R, Bartz J, et al. The active monitoring of oxytocin research evidence (AMORE) platform. PSYCHONEUROENDOCRINOLOGY. 2026;185.
IEEE
[1]
I. Iversen et al., “The active monitoring of oxytocin research evidence (AMORE) platform,” PSYCHONEUROENDOCRINOLOGY, vol. 185, 2026.
@article{01KEY2VRTGM65W7WDG6DE5D4CP,
  abstract     = {{Oxytocin, an evolutionarily conserved neuropeptide, plays a crucial role in various physiological and behavioural processes, offering potential therapeutic benefits for several psychiatric and neurodevelopmental conditions. Despite its promise, oxytocin research has been marked by inconsistent results concerning its therapeutic applications and underlying mechanisms. Performing a systematic review and meta-analysis is a popular approach to shed light on mixed findings in a body of literature; however, they can become quickly outdated as new evidence becomes available. Given these challenges, research on the links between oxytocin and biobehavioural outcomes is ideally positioned for the adoption of 'living' meta-analyses, which allow for the continuous integration of new data and updated conclusions. Here we introduce the Active Monitoring of Oxytocin Research Evidence (AMORE) platform (https://amore-project.org), which is a hub that aggregates articles and materials associated with living meta-analyses for biobehavioural oxytocin research in humans. Developed through consensus among 24 expert researchers, a standardized framework was established that either requires or recommends practices ensuring transparency and rigor in living meta-analyses featured on the AMORE platform. Overall, AMORE has been designed to advance human oxytocin biobehavioural research by the timely integration of emerging evidence through transparent living meta-analyses. To date, two living meta-analysis projects at different stages of publication are hosted on AMORE, demonstrating the platform's practical application.}},
  articleno    = {{107713}},
  author       = {{Iversen, IA and Alaerts, K and Bakermans-Kranenburg, M and Becker, B and Blair, RJ and Bartz, JA and Connelly, JJ and Ditzen, B and Ebner, NC and Kang, H and Lawson, EA and Lonfeldt, NN and Moerkerke, Matthijs and Montag, C and Mora-Jensen, A-RC and Horta, M and Peled-Avron, L and Procyshyn, TL and Sartorius, AI and Scheele, D and Schneider, E and Theofanopoulou, C and Yamasue, H and Quintana, DS}},
  issn         = {{0306-4530}},
  journal      = {{PSYCHONEUROENDOCRINOLOGY}},
  keywords     = {{Living meta-analysis,Systematic Review,Evidence synthesis,Oxytocin,Transparency,RANDOMIZED CONTROLLED-TRIAL,INTRANASAL OXYTOCIN,SYSTEMATIC REVIEWS,DEPRESSIVE-DISORDERS,ENDOGENOUS OXYTOCIN,MATERNAL-BEHAVIOR,EXPOSURE THERAPY,SOCIAL COGNITION,RECEPTOR,INDIVIDUALS}},
  language     = {{eng}},
  pages        = {{12}},
  title        = {{The active monitoring of oxytocin research evidence (AMORE) platform}},
  url          = {{http://doi.org/10.1016/j.psyneuen.2025.107713}},
  volume       = {{185}},
  year         = {{2026}},
}

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