Neuroendocrine tumors in the stomach : an epidemiological analysis of Belgian Cancer Registry data 2010–2019
- Author
- Marlies Maly, Eduard Callebout (UGent) , Suzane MOURA RIBEIRO (UGent) , Anne Hoorens (UGent) , Saskia Carton, Pieter‐Jan Cuyle, Timon Vandamme, Ivan Borbath, Pieter Demetter, Nancy Van Damme, Liesbet Van Eycken, Chris Verslype and Karen Geboes (UGent)
- Organization
- Abstract
- The prevalence of gastric NEN is estimated worldwide at 8.9% of all gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN) and only 0.3%-1% of all gastric neoplasms, but is rising in the last decades. The aim of this project was to map the epidemiology of gastric neuroendocrine neoplasm (gNEN) in Belgium. This is a population-wide retrospective cohort study over 10 years (2010-2019), based on data from the Belgian Cancer Registry. A total of 641 patients were included; 605 patients with gNEN and 36 with MiNEN. The AAIR of gNEN was 0.67 per 100,000 person-years, increasing over the years and with a slight female predominance (55.4%). Neuroendocrine carcinoma (NEC) accounted for 15.7% (N = 95), with an AAIR of 0.11 per 100,000 person-years. The other 510 patients were diagnosed with gNET: G1 NET was most prevalent (54.3%) followed by G2 (32.5%) and G3 NET (3.5%). Concerning the clinical classification (type) of gNET, a diagnosis of type 1 tumors was presumed in 67.6%, type 3 tumors in 17.1% and type 2 tumors in 0.6% of patients. In only 3.8% of patients, the clinical classification was explicitly stated in the pathology report. Stage IV tumors were diagnosed in 13.4% (N = 81). A favorable evolution in pathology reporting is seen. Some variables-for example, clinical classification of gNET-were heavily underreported, stressing the importance of registries integrating clinical and pathological information.
- Keywords
- gastric tumor, neuroendocrine carcinoma, neuroendocrine neoplasm, neuroendocrine tumor, MANAGEMENT
Downloads
-
(...).pdf
- full text (Published version)
- |
- UGent only
- |
- |
- 1.09 MB
Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-01JW5APD3NR4VHXECCYTK87BDA
- MLA
- Maly, Marlies, et al. “Neuroendocrine Tumors in the Stomach : An Epidemiological Analysis of Belgian Cancer Registry Data 2010–2019.” JOURNAL OF NEUROENDOCRINOLOGY, vol. 37, no. 1, 2025, doi:10.1111/jne.13473.
- APA
- Maly, M., Callebout, E., MOURA RIBEIRO, S., Hoorens, A., Carton, S., Cuyle, P., … Geboes, K. (2025). Neuroendocrine tumors in the stomach : an epidemiological analysis of Belgian Cancer Registry data 2010–2019. JOURNAL OF NEUROENDOCRINOLOGY, 37(1). https://doi.org/10.1111/jne.13473
- Chicago author-date
- Maly, Marlies, Eduard Callebout, Suzane MOURA RIBEIRO, Anne Hoorens, Saskia Carton, Pieter‐Jan Cuyle, Timon Vandamme, et al. 2025. “Neuroendocrine Tumors in the Stomach : An Epidemiological Analysis of Belgian Cancer Registry Data 2010–2019.” JOURNAL OF NEUROENDOCRINOLOGY 37 (1). https://doi.org/10.1111/jne.13473.
- Chicago author-date (all authors)
- Maly, Marlies, Eduard Callebout, Suzane MOURA RIBEIRO, Anne Hoorens, Saskia Carton, Pieter‐Jan Cuyle, Timon Vandamme, Ivan Borbath, Pieter Demetter, Nancy Van Damme, Liesbet Van Eycken, Chris Verslype, and Karen Geboes. 2025. “Neuroendocrine Tumors in the Stomach : An Epidemiological Analysis of Belgian Cancer Registry Data 2010–2019.” JOURNAL OF NEUROENDOCRINOLOGY 37 (1). doi:10.1111/jne.13473.
- Vancouver
- 1.Maly M, Callebout E, MOURA RIBEIRO S, Hoorens A, Carton S, Cuyle P, et al. Neuroendocrine tumors in the stomach : an epidemiological analysis of Belgian Cancer Registry data 2010–2019. JOURNAL OF NEUROENDOCRINOLOGY. 2025;37(1).
- IEEE
- [1]M. Maly et al., “Neuroendocrine tumors in the stomach : an epidemiological analysis of Belgian Cancer Registry data 2010–2019,” JOURNAL OF NEUROENDOCRINOLOGY, vol. 37, no. 1, 2025.
@article{01JW5APD3NR4VHXECCYTK87BDA,
abstract = {{The prevalence of gastric NEN is estimated worldwide at 8.9% of all gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN) and only 0.3%-1% of all gastric neoplasms, but is rising in the last decades. The aim of this project was to map the epidemiology of gastric neuroendocrine neoplasm (gNEN) in Belgium. This is a population-wide retrospective cohort study over 10 years (2010-2019), based on data from the Belgian Cancer Registry. A total of 641 patients were included; 605 patients with gNEN and 36 with MiNEN. The AAIR of gNEN was 0.67 per 100,000 person-years, increasing over the years and with a slight female predominance (55.4%). Neuroendocrine carcinoma (NEC) accounted for 15.7% (N = 95), with an AAIR of 0.11 per 100,000 person-years. The other 510 patients were diagnosed with gNET: G1 NET was most prevalent (54.3%) followed by G2 (32.5%) and G3 NET (3.5%). Concerning the clinical classification (type) of gNET, a diagnosis of type 1 tumors was presumed in 67.6%, type 3 tumors in 17.1% and type 2 tumors in 0.6% of patients. In only 3.8% of patients, the clinical classification was explicitly stated in the pathology report. Stage IV tumors were diagnosed in 13.4% (N = 81). A favorable evolution in pathology reporting is seen. Some variables-for example, clinical classification of gNET-were heavily underreported, stressing the importance of registries integrating clinical and pathological information.}},
articleno = {{e13473}},
author = {{Maly, Marlies and Callebout, Eduard and MOURA RIBEIRO, Suzane and Hoorens, Anne and Carton, Saskia and Cuyle, Pieter‐Jan and Vandamme, Timon and Borbath, Ivan and Demetter, Pieter and Van Damme, Nancy and Van Eycken, Liesbet and Verslype, Chris and Geboes, Karen}},
issn = {{0953-8194}},
journal = {{JOURNAL OF NEUROENDOCRINOLOGY}},
keywords = {{gastric tumor,neuroendocrine carcinoma,neuroendocrine neoplasm,neuroendocrine tumor,MANAGEMENT}},
language = {{eng}},
number = {{1}},
pages = {{7}},
title = {{Neuroendocrine tumors in the stomach : an epidemiological analysis of Belgian Cancer Registry data 2010–2019}},
url = {{http://doi.org/10.1111/jne.13473}},
volume = {{37}},
year = {{2025}},
}
- Altmetric
- View in Altmetric
- Web of Science
- Times cited: