@article{01JW3BSFMTM28PM33PWSQH03MX,
  abstract     = {{Background Current guidelines lack clarity regarding the appropriate use of preoperative ultrasound-guided (EUS) biopsy and receptor positron emission tomography (SSTR PET) imaging for pancreatic neuroendocrine tumors (PNETs). This study aims to reach expert consensus on the optimal sequencing of SSTR PET and EUS biopsy in the diagnostic workup and management of patients with suspected PNETs. Methods A three-round modified Delphi process was used. A multidisciplinary panel of experts was recruited via snowball sampling. A set of 22 baseline statements pertaining to diagnostic workup, imaging, and biopsy was developed based on literature review and feedback obtained through a focus group. Survey rounds were conducted electronically and anonymously. A panel of international experts was asked to indicate whether they agreed, disagreed, or lacked the appropriate background to answer each statement. Of the 55 experts invited, 38 (69%) accepted to participate. Consensus was achieved with > 80% agreement. Results Response rates were 97%, 100%, and 100% in rounds 1, 2, and 3, respectively. Following rounds 1 and 2, 29 final statements achieved consensus in the following three domains: diagnostic workup (15 statements), imaging (nine statements), and tissue sampling (five statements). Cronbach's alpha value, a measure of internal consistency, was 0.91 and 0.85 for rounds 1 and 2, respectively. The final set of statements achieved a 95% approval rate in round 3. Conclusion This international Delphi study provides expert consensus-based guidance on the appropriate use of EUS biopsy in the diagnostic workup of PNETs in the era of SSTR PET imaging.}},
  author       = {{Casey, Megan and Tozzi, Francesca and Wang, Jaeyun and Park, Keon Min and Bergsland, Emily and Hope, Thomas and Kennecke, Hagen F. and Rose, J. Bart and Babicky, Michele and Irani, Shayan S. and El-Hayek, Kevin M. and Hilal, Mohammad Abu and Asbun, Horacio J. and Cleary, Sean and Smeets, Peter and Berrevoet, Frederik and Adam, Mohamed and Rashidian, Niki and Alseidi, Adnan and Chauhan, Aman and Bellizzi, Andrew M. and Fretland, Åsmund A. and Visser, Brendan C. and Katona, Bryson W. and Halperin, Daniel and Chen, Delphine L. and Nakakura, Eric and Mittra, Erik and Rocha, Flavio G. and Kim, Grace E. and Soares, Heloisa and Hoorens, Anne and Maxwell, Jess and Loree, Jonathan M. and Geboes, Karen and Lee, Linda and Larsen, Michael H. and Dua, Monica and Arain, Mustafa and Mallak, Nadine and Joseph, Nancy and Raj, Nitya and Hindryckx, Pieter and Dai, Sun-Chuan and Halfdanarson, Thorvardur R. and Van den Broeck, Bliede and PNET Diag Res Grp, [missing]}},
  issn         = {{0930-2794}},
  journal      = {{SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES}},
  keywords     = {{Pancreatic neuroendocrine tumors,Somatostatin receptor positron emission tomography,Tissue sampling,Expert consensus,Diagnostic protocol,Ultrasound-guided biopsy,POPULATION-BASED ANALYSIS,SURGICAL-MANAGEMENT,GUIDELINES,SURVEILLANCE,BIOPSY,CARE}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{3435--3446}},
  title        = {{Appropriate use of tissue sampling and somatostatin receptor PET imaging in the diagnosis of pancreatic neuroendocrine tumors : results of an International Delphi Consensus}},
  url          = {{http://doi.org/10.1007/s00464-025-11667-8}},
  volume       = {{39}},
  year         = {{2025}},
}

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