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Deep learning-based event counting for apnea-hypopnea index estimation using recursive spiking neural networks

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Abstract
Objective: To develop a novel method for improved screening of sleep apnea in home environments, focusing on reliable estimation of the Apnea-Hypopnea Index (AHI) without the need for highly precise event localization. Methods: RSN-Count is introduced, a technique leveraging Spiking Neural Networks to directly count apneic events in recorded signals. This approach aims to reduce dependence on the exact time-based pinpointing of events, a potential source of variability in conventional analysis. Results: RSN-Count demonstrates a superior ability to quantify apneic events (AHI MAE 6.17 +/- 2.21) compared to established methods (AHI MAE 8.52 +/- 3.20) on a dataset of whole-night audio and SpO2 recordings (N = 33). This is particularly valuable for accurate AHI estimation, even in the absence of highly precise event localization. Conclusion: RSN-Count offers a promising improvement in sleep apnea screening within home settings. Its focus on event quantification enhances AHI estimation accuracy. Significance: This method addresses limitations in current sleep apnea diagnostics, potentially increasing screening accuracy and accessibility while reducing dependence on costly and complex polysomnography.
Keywords
SLEEP-APNEA, PREDICTION, SOUND, Sleep apnea detection, AHI estimation, deep learning, deep learning, spiking neural networks, spiking neural networks, wearables, wearables, wearables

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Citation

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MLA
Werthen-Brabants, Lorin, et al. “Deep Learning-Based Event Counting for Apnea-Hypopnea Index Estimation Using Recursive Spiking Neural Networks.” IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, vol. 72, no. 4, 2025, pp. 1306–15, doi:10.1109/TBME.2024.3498097.
APA
Werthen-Brabants, L., Castillo-Escario, Y., Groenendaal, W., Jane, R., Dhaene, T., & Deschrijver, D. (2025). Deep learning-based event counting for apnea-hypopnea index estimation using recursive spiking neural networks. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 72(4), 1306–1315. https://doi.org/10.1109/TBME.2024.3498097
Chicago author-date
Werthen-Brabants, Lorin, Yolanda Castillo-Escario, Willemijn Groenendaal, Raimon Jane, Tom Dhaene, and Dirk Deschrijver. 2025. “Deep Learning-Based Event Counting for Apnea-Hypopnea Index Estimation Using Recursive Spiking Neural Networks.” IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING 72 (4): 1306–15. https://doi.org/10.1109/TBME.2024.3498097.
Chicago author-date (all authors)
Werthen-Brabants, Lorin, Yolanda Castillo-Escario, Willemijn Groenendaal, Raimon Jane, Tom Dhaene, and Dirk Deschrijver. 2025. “Deep Learning-Based Event Counting for Apnea-Hypopnea Index Estimation Using Recursive Spiking Neural Networks.” IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING 72 (4): 1306–1315. doi:10.1109/TBME.2024.3498097.
Vancouver
1.
Werthen-Brabants L, Castillo-Escario Y, Groenendaal W, Jane R, Dhaene T, Deschrijver D. Deep learning-based event counting for apnea-hypopnea index estimation using recursive spiking neural networks. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING. 2025;72(4):1306–15.
IEEE
[1]
L. Werthen-Brabants, Y. Castillo-Escario, W. Groenendaal, R. Jane, T. Dhaene, and D. Deschrijver, “Deep learning-based event counting for apnea-hypopnea index estimation using recursive spiking neural networks,” IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, vol. 72, no. 4, pp. 1306–1315, 2025.
@article{01JQXFR3GCY7TX1F5BYQ9DHSP8,
  abstract     = {{Objective: To develop a novel method for improved screening of sleep apnea in home environments, focusing on reliable estimation of the Apnea-Hypopnea Index (AHI) without the need for highly precise event localization. Methods: RSN-Count is introduced, a technique leveraging Spiking Neural Networks to directly count apneic events in recorded signals. This approach aims to reduce dependence on the exact time-based pinpointing of events, a potential source of variability in conventional analysis. Results: RSN-Count demonstrates a superior ability to quantify apneic events (AHI MAE 6.17 +/- 2.21) compared to established methods (AHI MAE 8.52 +/- 3.20) on a dataset of whole-night audio and SpO2 recordings (N = 33). This is particularly valuable for accurate AHI estimation, even in the absence of highly precise event localization. Conclusion: RSN-Count offers a promising improvement in sleep apnea screening within home settings. Its focus on event quantification enhances AHI estimation accuracy. Significance: This method addresses limitations in current sleep apnea diagnostics, potentially increasing screening accuracy and accessibility while reducing dependence on costly and complex polysomnography.}},
  author       = {{Werthen-Brabants, Lorin and Castillo-Escario, Yolanda and Groenendaal, Willemijn and Jane, Raimon and Dhaene, Tom and Deschrijver, Dirk}},
  issn         = {{0018-9294}},
  journal      = {{IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING}},
  keywords     = {{SLEEP-APNEA,PREDICTION,SOUND,Sleep apnea detection,AHI estimation,deep learning,deep learning,spiking neural networks,spiking neural networks,wearables,wearables,wearables}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{1306--1315}},
  title        = {{Deep learning-based event counting for apnea-hypopnea index estimation using recursive spiking neural networks}},
  url          = {{http://doi.org/10.1109/TBME.2024.3498097}},
  volume       = {{72}},
  year         = {{2025}},
}

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