Poly(N-isopropylacrylamide) and its copolymers : a review on recent advances in the areas of sensing and biosensing
- Author
- Anubhab Das, Anashwara Babu, Sourav Chakraborty, Joachim Van Guyse, Richard Hoogenboom (UGent) and Samarendra Maji
- Organization
- Abstract
- Stimuli-responsive polymers have received increasing attention for various applications due to their ability to adapt physical and chemical properties in response to external environmental stimuli. In this regard, poly(N-isopropylacrylamide) (PNIPAM) is the most extensively studied stimuli-responsive polymer and, consequently has been prominently featured in (bio)-sensor development, adaptive coating technology, drug delivery, wound healing, tissue regeneration, artificial actuator design, sensor technology, responsive coatings, and soft robotics. This success can be mainly attributed to the accessible and versatile nature of the PNIPAM platform, thus allowing the synthesis of a wide variety of copolymer architectures, topologies and compositions. Within this review, the structural and compositional features of PNIPAM-based materials in sensor and biosensor applications are discussed with a focus on the literature from 2016 until now. The reader is provided with the current state of the art regarding PNIPAM-based sensor development and their molecular design. Finally, the challenges ahead in the successful implementation of PNIPAM-based sensors are highlighted, as well as the opportunities in the rational design of improved PNIPAM-based sensors. Altogether, this review provides comprehensive insights into the exciting and rapidly expanding field of PNIPAM-based sensing systems, which will benefit the chemical, pharmaceutical, textile, and biotech industries is believed.
- Keywords
- biosensor, poly(N-isopropyl acrylamide), sensor, smart material, thermoresponsive polymer, N-ISOPROPYLACRYLAMIDE MICROGELS, VOLUME PHASE-TRANSITIONS, PH-RESPONSIVE POLYMERS, DETECTING SOLUTION PH, LABEL-FREE DETECTION, ORGANIC-DYE REMOVAL, FLUORESCENT SENSOR, ELECTROCHEMICAL DETECTION, SELECTIVE DETECTION, GOLD NANOPARTICLES
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-01JNZN61RKBG4ET4BG3PMQM85H
- MLA
- Das, Anubhab, et al. “Poly(N-Isopropylacrylamide) and Its Copolymers : A Review on Recent Advances in the Areas of Sensing and Biosensing.” ADVANCED FUNCTIONAL MATERIALS, vol. 34, no. 37, 2024, doi:10.1002/adfm.202402432.
- APA
- Das, A., Babu, A., Chakraborty, S., Van Guyse, J., Hoogenboom, R., & Maji, S. (2024). Poly(N-isopropylacrylamide) and its copolymers : a review on recent advances in the areas of sensing and biosensing. ADVANCED FUNCTIONAL MATERIALS, 34(37). https://doi.org/10.1002/adfm.202402432
- Chicago author-date
- Das, Anubhab, Anashwara Babu, Sourav Chakraborty, Joachim Van Guyse, Richard Hoogenboom, and Samarendra Maji. 2024. “Poly(N-Isopropylacrylamide) and Its Copolymers : A Review on Recent Advances in the Areas of Sensing and Biosensing.” ADVANCED FUNCTIONAL MATERIALS 34 (37). https://doi.org/10.1002/adfm.202402432.
- Chicago author-date (all authors)
- Das, Anubhab, Anashwara Babu, Sourav Chakraborty, Joachim Van Guyse, Richard Hoogenboom, and Samarendra Maji. 2024. “Poly(N-Isopropylacrylamide) and Its Copolymers : A Review on Recent Advances in the Areas of Sensing and Biosensing.” ADVANCED FUNCTIONAL MATERIALS 34 (37). doi:10.1002/adfm.202402432.
- Vancouver
- 1.Das A, Babu A, Chakraborty S, Van Guyse J, Hoogenboom R, Maji S. Poly(N-isopropylacrylamide) and its copolymers : a review on recent advances in the areas of sensing and biosensing. ADVANCED FUNCTIONAL MATERIALS. 2024;34(37).
- IEEE
- [1]A. Das, A. Babu, S. Chakraborty, J. Van Guyse, R. Hoogenboom, and S. Maji, “Poly(N-isopropylacrylamide) and its copolymers : a review on recent advances in the areas of sensing and biosensing,” ADVANCED FUNCTIONAL MATERIALS, vol. 34, no. 37, 2024.
@article{01JNZN61RKBG4ET4BG3PMQM85H,
abstract = {{Stimuli-responsive polymers have received increasing attention for various applications due to their ability to adapt physical and chemical properties in response to external environmental stimuli. In this regard, poly(N-isopropylacrylamide) (PNIPAM) is the most extensively studied stimuli-responsive polymer and, consequently has been prominently featured in (bio)-sensor development, adaptive coating technology, drug delivery, wound healing, tissue regeneration, artificial actuator design, sensor technology, responsive coatings, and soft robotics. This success can be mainly attributed to the accessible and versatile nature of the PNIPAM platform, thus allowing the synthesis of a wide variety of copolymer architectures, topologies and compositions. Within this review, the structural and compositional features of PNIPAM-based materials in sensor and biosensor applications are discussed with a focus on the literature from 2016 until now. The reader is provided with the current state of the art regarding PNIPAM-based sensor development and their molecular design. Finally, the challenges ahead in the successful implementation of PNIPAM-based sensors are highlighted, as well as the opportunities in the rational design of improved PNIPAM-based sensors. Altogether, this review provides comprehensive insights into the exciting and rapidly expanding field of PNIPAM-based sensing systems, which will benefit the chemical, pharmaceutical, textile, and biotech industries is believed.}},
articleno = {{2402432}},
author = {{Das, Anubhab and Babu, Anashwara and Chakraborty, Sourav and Van Guyse, Joachim and Hoogenboom, Richard and Maji, Samarendra}},
issn = {{1616-301X}},
journal = {{ADVANCED FUNCTIONAL MATERIALS}},
keywords = {{biosensor,poly(N-isopropyl acrylamide),sensor,smart material,thermoresponsive polymer,N-ISOPROPYLACRYLAMIDE MICROGELS,VOLUME PHASE-TRANSITIONS,PH-RESPONSIVE POLYMERS,DETECTING SOLUTION PH,LABEL-FREE DETECTION,ORGANIC-DYE REMOVAL,FLUORESCENT SENSOR,ELECTROCHEMICAL DETECTION,SELECTIVE DETECTION,GOLD NANOPARTICLES}},
language = {{eng}},
number = {{37}},
pages = {{71}},
title = {{Poly(N-isopropylacrylamide) and its copolymers : a review on recent advances in the areas of sensing and biosensing}},
url = {{http://doi.org/10.1002/adfm.202402432}},
volume = {{34}},
year = {{2024}},
}
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