@article{01JN3ZEZNJKANMWBGSE19MBJDS,
  abstract     = {{Purpose: This study evaluates whether the Benefits of Obtaining Ownership Systematically Together in pediatric Advance Care Planning (BOOST pACP) intervention improves parent-adolescent communication compared to care as usual. Methods: In this multi-center parallel-group superiority trial, adolescent patients (10-18 years old) diagnosed with cancer and their parent(s) were randomized with a 1:1 allocation to a pACP intervention or care as usual. The primary endpoint was the adolescents' assessment of quality of parent-adolescent communication at 3 months, and the secondary was quality of parent-adolescent communication at 7 months. Results: Forty-nine families were enrolled (28% enrollment rate) between March 2021 and March 2023. No significant differences in parent-adolescent communication were observed between the BOOST and care as usual groups at 3 months (T1) (baseline-adjusted mean difference = 1.4; 95% CI -4.1 to 6.9; p = 0.608), effect size 0.13. Similarly, at 7 months (T2) differences were not significant (baseline-adjusted mean difference = 5.2; 95% CI -0.6 to 11.0; p = 0.077), effect size 0.49 (and 0.67 for father-adolescent communication). No significant differences in anxiety scores of adolescents and parents were found and no adverse events were reported. Conclusion: The BOOST pACP intervention did not significantly improve parent-adolescent communication for adolescents with cancer and their parents at 3 months after baseline. However, the results indicate it might have a clinical impact in later stages of the follow-up period. Limitations of this study are the underpowered sample size and the lack of validated questionnaires for specific ACP communication. Clinical trial registration: ISRCTN, number 33228289 https://doi.org/10.1186/ISRCTN33228289.}},
  articleno    = {{102823}},
  author       = {{van Driessche, Anne and Cohen, Joachim and Deliens, Luc and Kars, Marijke C. and Willems, Leen and De Buyser, Stefanie and Verlooy, Joris and Renard, Marleen and Eecloo, Kim and De Vleminck, Aline and Beernaert, Kim}},
  issn         = {{1462-3889}},
  journal      = {{EUROPEAN JOURNAL OF ONCOLOGY NURSING}},
  keywords     = {{Advance care planning,Parent-adolescent communication,Pediatric oncology,Randomized controlled trial,YOUNG-PEOPLE,CHILDREN}},
  language     = {{eng}},
  pages        = {{9}},
  title        = {{Multi-center randomized controlled trial on advance care planning for adolescents with cancer and their parents : impact on parent-adolescent communication}},
  url          = {{http://doi.org/10.1016/j.ejon.2025.102823}},
  volume       = {{75}},
  year         = {{2025}},
}

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