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Should we be treating affective symptoms, like anxiety and depression which may be related to LUTD in patients with OAB? ICI‐RS 2024

Mauro Van den Ende (UGent) , Apostolos Apostolidis, Sanjay Sinha, George Bou Kheir (UGent) , Rayan Mohamed‐Ahmed, Caroline Selai, Paul Abrams and Desiree Vrijens
(2025) NEUROUROLOGY AND URODYNAMICS. 44(3). p.661-667
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Organization
Abstract
AimsTo discuss the role of screening and treatment of affective symptoms, like anxiety and depression in patients with LUTD. A review of the literature regarding the bidirectional association and multidisciplinary approaches integrating psychometric assessments with personalized treatment plans to improve diagnostic accuracy and therapeutic outcomes of LUTD.MethodsThis review summarizes discussions and a narrative review of (recent) literature during an International Consultation on Incontinence-Research Society 2024 research proposal with respect to the role of screening for anxiety and depression, effect of mental health symptoms on treatment outcomes and future implications.ResultsConsensus recognized the importance to incorporate attention to anxiety and depression in relation to LUTD. The awareness of this association can lead to better outcomes. Future research projects are proposed to evaluate the bidirectional relationship.ConclusionThe relationship between affective symptoms and LUTD underscores the need for integrated treatment approaches that address both psychological and urological dimensions. Further research is required to identify specific patient subgroups that would benefit most from these interventions, to develop standardized screening tools, and to refine treatment protocols. Multidisciplinary care, incorporating psychological assessment and personalized treatment strategies, could enhance outcomes for LUTD patients.
Keywords
URINARY-TRACT SYMPTOMS, OVERACTIVE BLADDER, TREATMENT RESPONSE, PRIMARY-CARE, INCONTINENCE, PREDICTORS, INSTRUMENTS, MICTURITION, DULOXETINE, DISORDERS

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MLA
Van den Ende, Mauro, et al. “Should We Be Treating Affective Symptoms, like Anxiety and Depression Which May Be Related to LUTD in Patients with OAB? ICI‐RS 2024.” NEUROUROLOGY AND URODYNAMICS, vol. 44, no. 3, 2025, pp. 661–67, doi:10.1002/nau.25662.
APA
Van den Ende, M., Apostolidis, A., Sinha, S., Bou Kheir, G., Mohamed‐Ahmed, R., Selai, C., … Vrijens, D. (2025). Should we be treating affective symptoms, like anxiety and depression which may be related to LUTD in patients with OAB? ICI‐RS 2024. NEUROUROLOGY AND URODYNAMICS, 44(3), 661–667. https://doi.org/10.1002/nau.25662
Chicago author-date
Van den Ende, Mauro, Apostolos Apostolidis, Sanjay Sinha, George Bou Kheir, Rayan Mohamed‐Ahmed, Caroline Selai, Paul Abrams, and Desiree Vrijens. 2025. “Should We Be Treating Affective Symptoms, like Anxiety and Depression Which May Be Related to LUTD in Patients with OAB? ICI‐RS 2024.” NEUROUROLOGY AND URODYNAMICS 44 (3): 661–67. https://doi.org/10.1002/nau.25662.
Chicago author-date (all authors)
Van den Ende, Mauro, Apostolos Apostolidis, Sanjay Sinha, George Bou Kheir, Rayan Mohamed‐Ahmed, Caroline Selai, Paul Abrams, and Desiree Vrijens. 2025. “Should We Be Treating Affective Symptoms, like Anxiety and Depression Which May Be Related to LUTD in Patients with OAB? ICI‐RS 2024.” NEUROUROLOGY AND URODYNAMICS 44 (3): 661–667. doi:10.1002/nau.25662.
Vancouver
1.
Van den Ende M, Apostolidis A, Sinha S, Bou Kheir G, Mohamed‐Ahmed R, Selai C, et al. Should we be treating affective symptoms, like anxiety and depression which may be related to LUTD in patients with OAB? ICI‐RS 2024. NEUROUROLOGY AND URODYNAMICS. 2025;44(3):661–7.
IEEE
[1]
M. Van den Ende et al., “Should we be treating affective symptoms, like anxiety and depression which may be related to LUTD in patients with OAB? ICI‐RS 2024,” NEUROUROLOGY AND URODYNAMICS, vol. 44, no. 3, pp. 661–667, 2025.
@article{01JHTGPNT9A7N3N5ASCP1E8DBR,
  abstract     = {{AimsTo discuss the role of screening and treatment of affective symptoms, like anxiety and depression in patients with LUTD. A review of the literature regarding the bidirectional association and multidisciplinary approaches integrating psychometric assessments with personalized treatment plans to improve diagnostic accuracy and therapeutic outcomes of LUTD.MethodsThis review summarizes discussions and a narrative review of (recent) literature during an International Consultation on Incontinence-Research Society 2024 research proposal with respect to the role of screening for anxiety and depression, effect of mental health symptoms on treatment outcomes and future implications.ResultsConsensus recognized the importance to incorporate attention to anxiety and depression in relation to LUTD. The awareness of this association can lead to better outcomes. Future research projects are proposed to evaluate the bidirectional relationship.ConclusionThe relationship between affective symptoms and LUTD underscores the need for integrated treatment approaches that address both psychological and urological dimensions. Further research is required to identify specific patient subgroups that would benefit most from these interventions, to develop standardized screening tools, and to refine treatment protocols. Multidisciplinary care, incorporating psychological assessment and personalized treatment strategies, could enhance outcomes for LUTD patients.}},
  author       = {{Van den Ende, Mauro and Apostolidis, Apostolos and Sinha, Sanjay and Bou Kheir, George and Mohamed‐Ahmed, Rayan and Selai, Caroline and Abrams, Paul and Vrijens, Desiree}},
  issn         = {{0733-2467}},
  journal      = {{NEUROUROLOGY AND URODYNAMICS}},
  keywords     = {{URINARY-TRACT SYMPTOMS,OVERACTIVE BLADDER,TREATMENT RESPONSE,PRIMARY-CARE,INCONTINENCE,PREDICTORS,INSTRUMENTS,MICTURITION,DULOXETINE,DISORDERS}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{661--667}},
  title        = {{Should we be treating affective symptoms, like anxiety and depression which may be related to LUTD in patients with OAB? ICI‐RS 2024}},
  url          = {{http://doi.org/10.1002/nau.25662}},
  volume       = {{44}},
  year         = {{2025}},
}
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