Nurse-led self-management support after organ transplantation : a multicenter, stepped-wedge randomized controlled trial
- Author
- Regina van Zanten, Monique van Dijk, Joost van Rosmalen, Denise K. Beck, AnneLoes van Staa, Ann Van Hecke (UGent) , Emma K. Massey and [missing] AanZETStudy Grp
- Organization
- Abstract
- In this unblinded multi-center stepped-wedge randomized controlled trial the effectiveness of the nurse-led ZENN-intervention was tested in promoting self-management skills in comparison to standard care among heart, lung and kidney transplant recipients. This intervention is based on behaviour change theories and was conducted in four sessions over 6 months at the outpatient clinic. The experimental group received standard care, plus the ZENN-intervention, while the control group received only standard care. Both groups completed questionnaires at baseline, at 6 months and 1 year follow-up. At baseline, the experimental group (n = 69) scored significantly lower than the control group (n = 106) on the primary outcome Skills and Technique Acquisition (STA). No significant between-group differences were found on the secondary outcomes self-management, self-regulation, quality of life and medication adherence at T1 and T2. There was a significant increase on the self-management scale STA between T0 and T1 in the experimental group. Therefore, participants included in the experimental group had lower self-management skills at baseline and reported significant improvement after completing the intervention. No significant intervention effect was found in the primary analysis, however, for recipients with reduced self-management skills the intervention may be beneficial.
- Keywords
- nurse practioners, patient participation, motivation, goal, self-efficacy, HEALTH, INTERVENTION, RECIPIENTS, ATTITUDES, VALIDITY, PEOPLE
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-01JHHTNZFEYT0RD445TV3HF1RF
- MLA
- van Zanten, Regina, et al. “Nurse-Led Self-Management Support after Organ Transplantation : A Multicenter, Stepped-Wedge Randomized Controlled Trial.” TRANSPLANT INTERNATIONAL, vol. 37, 2025, doi:10.3389/ti.2024.13175.
- APA
- van Zanten, R., van Dijk, M., van Rosmalen, J., Beck, D. K., van Staa, A., Van Hecke, A., … AanZETStudy Grp, [missing]. (2025). Nurse-led self-management support after organ transplantation : a multicenter, stepped-wedge randomized controlled trial. TRANSPLANT INTERNATIONAL, 37. https://doi.org/10.3389/ti.2024.13175
- Chicago author-date
- Zanten, Regina van, Monique van Dijk, Joost van Rosmalen, Denise K. Beck, AnneLoes van Staa, Ann Van Hecke, Emma K. Massey, and [missing] AanZETStudy Grp. 2025. “Nurse-Led Self-Management Support after Organ Transplantation : A Multicenter, Stepped-Wedge Randomized Controlled Trial.” TRANSPLANT INTERNATIONAL 37. https://doi.org/10.3389/ti.2024.13175.
- Chicago author-date (all authors)
- van Zanten, Regina, Monique van Dijk, Joost van Rosmalen, Denise K. Beck, AnneLoes van Staa, Ann Van Hecke, Emma K. Massey, and [missing] AanZETStudy Grp. 2025. “Nurse-Led Self-Management Support after Organ Transplantation : A Multicenter, Stepped-Wedge Randomized Controlled Trial.” TRANSPLANT INTERNATIONAL 37. doi:10.3389/ti.2024.13175.
- Vancouver
- 1.van Zanten R, van Dijk M, van Rosmalen J, Beck DK, van Staa A, Van Hecke A, et al. Nurse-led self-management support after organ transplantation : a multicenter, stepped-wedge randomized controlled trial. TRANSPLANT INTERNATIONAL. 2025;37.
- IEEE
- [1]R. van Zanten et al., “Nurse-led self-management support after organ transplantation : a multicenter, stepped-wedge randomized controlled trial,” TRANSPLANT INTERNATIONAL, vol. 37, 2025.
@article{01JHHTNZFEYT0RD445TV3HF1RF,
abstract = {{In this unblinded multi-center stepped-wedge randomized controlled trial the effectiveness of the nurse-led ZENN-intervention was tested in promoting self-management skills in comparison to standard care among heart, lung and kidney transplant recipients. This intervention is based on behaviour change theories and was conducted in four sessions over 6 months at the outpatient clinic. The experimental group received standard care, plus the ZENN-intervention, while the control group received only standard care. Both groups completed questionnaires at baseline, at 6 months and 1 year follow-up. At baseline, the experimental group (n = 69) scored significantly lower than the control group (n = 106) on the primary outcome Skills and Technique Acquisition (STA). No significant between-group differences were found on the secondary outcomes self-management, self-regulation, quality of life and medication adherence at T1 and T2. There was a significant increase on the self-management scale STA between T0 and T1 in the experimental group. Therefore, participants included in the experimental group had lower self-management skills at baseline and reported significant improvement after completing the intervention. No significant intervention effect was found in the primary analysis, however, for recipients with reduced self-management skills the intervention may be beneficial.}},
articleno = {{13175}},
author = {{van Zanten, Regina and van Dijk, Monique and van Rosmalen, Joost and Beck, Denise K. and van Staa, AnneLoes and Van Hecke, Ann and Massey, Emma K. and AanZETStudy Grp, [missing]}},
issn = {{0934-0874}},
journal = {{TRANSPLANT INTERNATIONAL}},
keywords = {{nurse practioners,patient participation,motivation,goal,self-efficacy,HEALTH,INTERVENTION,RECIPIENTS,ATTITUDES,VALIDITY,PEOPLE}},
language = {{eng}},
pages = {{13}},
title = {{Nurse-led self-management support after organ transplantation : a multicenter, stepped-wedge randomized controlled trial}},
url = {{http://doi.org/10.3389/ti.2024.13175}},
volume = {{37}},
year = {{2025}},
}
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