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Advancing (neuro)entrepreneurship cognition research through resting-state fMRI : a methodological brief

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Abstract
Despite many calls, functional brain magnetic resonance imaging (fMRI) studies are relatively rare in the domain of entrepreneurship research. This methodological brief presents the brain-imaging method of resting-state fMRI (rs-fMRI) and illustrates its application in neuroentrepreneurship for the first time. In contrast to the traditional task-based fMRI approach, rs-fMRI observes the brain in the absence of cognitive tasks or presentation of stimuli, which offers benefits for improving our understanding of the entrepreneurial mind. Here, we describe the method and provide methodological motivations for performing brain resting-state functional neuroimaging studies on entrepreneurs. In addition, we illustrate the use of seed-based correlation analysis, one of the most common analytical approaches for analyzing rs-fMRI data. In this illustration, we show that habitual entrepreneurs have increased functional connectivity between the insula (a region associated with cognitive flexibility) and the anterior prefrontal cortex (a key region for explorative choice) as compared to managers. This increased connectivity could help promote flexible behavior. Thus in brief, we provide an exemplar of a novel way to expand our understanding of the brain in the domain of entrepreneurship. We discuss possible directions for future research and challenges to be addressed to facilitate the inclusion of re-fMRI studies into neuroentrepreneurship.
Keywords
entrepreneur, manager, fMRI, neuroentrepreneurship, cognitive, flexibility, brain, FUNCTIONAL CONNECTIVITY, DECISION-MAKING, BRAIN, ENTREPRENEURIAL, PERSONALITY, RELIABILITY, CORTEX, TOOLBOX, FAILURE, NETWORK

Citation

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MLA
Ooms, Frédéric, et al. “Advancing (Neuro)Entrepreneurship Cognition Research through Resting-State FMRI : A Methodological Brief.” ENTREPRENEURSHIP THEORY AND PRACTICE, vol. 48, no. 2, 2024, pp. 719–41, doi:10.1177/10422587231170217.
APA
Ooms, F., Annen, J., Panda, R., Meunier, P., Tshibanda, L., Laureys, S., … Surlemont, B. (2024). Advancing (neuro)entrepreneurship cognition research through resting-state fMRI : a methodological brief. ENTREPRENEURSHIP THEORY AND PRACTICE, 48(2), 719–741. https://doi.org/10.1177/10422587231170217
Chicago author-date
Ooms, Frédéric, Jitka Annen, Rajanikant Panda, Paul Meunier, Luaba Tshibanda, Steven Laureys, Jeffrey M. Pollack, and Bernard Surlemont. 2024. “Advancing (Neuro)Entrepreneurship Cognition Research through Resting-State FMRI : A Methodological Brief.” ENTREPRENEURSHIP THEORY AND PRACTICE 48 (2): 719–41. https://doi.org/10.1177/10422587231170217.
Chicago author-date (all authors)
Ooms, Frédéric, Jitka Annen, Rajanikant Panda, Paul Meunier, Luaba Tshibanda, Steven Laureys, Jeffrey M. Pollack, and Bernard Surlemont. 2024. “Advancing (Neuro)Entrepreneurship Cognition Research through Resting-State FMRI : A Methodological Brief.” ENTREPRENEURSHIP THEORY AND PRACTICE 48 (2): 719–741. doi:10.1177/10422587231170217.
Vancouver
1.
Ooms F, Annen J, Panda R, Meunier P, Tshibanda L, Laureys S, et al. Advancing (neuro)entrepreneurship cognition research through resting-state fMRI : a methodological brief. ENTREPRENEURSHIP THEORY AND PRACTICE. 2024;48(2):719–41.
IEEE
[1]
F. Ooms et al., “Advancing (neuro)entrepreneurship cognition research through resting-state fMRI : a methodological brief,” ENTREPRENEURSHIP THEORY AND PRACTICE, vol. 48, no. 2, pp. 719–741, 2024.
@article{01JDMMQM4BMPG6M4FJTM8Q41Y6,
  abstract     = {{Despite many calls, functional brain magnetic resonance imaging (fMRI) studies are relatively rare in the domain of entrepreneurship research. This methodological brief presents the brain-imaging method of resting-state fMRI (rs-fMRI) and illustrates its application in neuroentrepreneurship for the first time. In contrast to the traditional task-based fMRI approach, rs-fMRI observes the brain in the absence of cognitive tasks or presentation of stimuli, which offers benefits for improving our understanding of the entrepreneurial mind. Here, we describe the method and provide methodological motivations for performing brain resting-state functional neuroimaging studies on entrepreneurs. In addition, we illustrate the use of seed-based correlation analysis, one of the most common analytical approaches for analyzing rs-fMRI data. In this illustration, we show that habitual entrepreneurs have increased functional connectivity between the insula (a region associated with cognitive flexibility) and the anterior prefrontal cortex (a key region for explorative choice) as compared to managers. This increased connectivity could help promote flexible behavior. Thus in brief, we provide an exemplar of a novel way to expand our understanding of the brain in the domain of entrepreneurship. We discuss possible directions for future research and challenges to be addressed to facilitate the inclusion of re-fMRI studies into neuroentrepreneurship.}},
  author       = {{Ooms, Frédéric and Annen, Jitka and Panda, Rajanikant and Meunier, Paul and Tshibanda, Luaba and Laureys, Steven and Pollack, Jeffrey M. and Surlemont, Bernard}},
  issn         = {{1042-2587}},
  journal      = {{ENTREPRENEURSHIP THEORY AND PRACTICE}},
  keywords     = {{entrepreneur,manager,fMRI,neuroentrepreneurship,cognitive,flexibility,brain,FUNCTIONAL CONNECTIVITY,DECISION-MAKING,BRAIN,ENTREPRENEURIAL,PERSONALITY,RELIABILITY,CORTEX,TOOLBOX,FAILURE,NETWORK}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{719--741}},
  title        = {{Advancing (neuro)entrepreneurship cognition research through resting-state fMRI : a methodological brief}},
  url          = {{http://doi.org/10.1177/10422587231170217}},
  volume       = {{48}},
  year         = {{2024}},
}

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