Academic Bibliography

 Search 200 years of publications by Ghent University researchers.
Advanced search
1 file | 2.07 MB
Add to list
  1. Search results
  2. Utility of icobrain for brain volumet...

Utility of icobrain for brain volumetry in multiple sclerosis clinical practice

Ai-Lan Nguyen, Maria Pia Sormani, Dana Horakova, Eva H Havrdova, Michael H Barnett, Nicola De Stefano, Marco Battaglini, Manuela Vaneckova, Elaine Lui, Frank Gaillard, et al.
(2024) MULTIPLE SCLEROSIS AND RELATED DISORDERS. 92.
Author
Organization
Abstract
Background Few studies on multiple sclerosis (MS) have explored the variability of percentage brain volume change (PBVC) measurements obtained from different clinical MRIs. In a retrospective multicentre cohort study, we quantified the variability of annualised PBVC in clinical MRIs. Methods Clinical MRIs of relapse-onset MS patients were assessed by icobrain. Volumetric data were analysed on same-scanner and different-scanner MRI pairs if they passed quality control criteria. Alignment similarity between two images had to be comparable to same-scanner scan-rescan images. Results Of 6826 MRIs, 85 % had appropriate volumetric sequences and 4446 serial MRI pairs were analysed. 3334 (75 %) MRI pairs from 1207 patients met the inclusions. The PBVC of included MRI pairs showed variance of 0.78 % for same-scanner pairs and 0.80 % for different-scanner pairs. Further selection of included MRI pairs with the best variance resulted in 1885 (42 %) MRI pairs with PBVC variance of 0.34 %. Excluded MRI pairs with poor alignment similarity had variances of 2.97 % for same-scanner pairs and 20.79 % for different-scanner pairs. Conclusion Icobrain should be utilised for PBVC determination only on selected MRIs with the best alignment similarity. Applying strict selection criteria for the included MRI pairs and longitudinal imaging on the same scanner remain mandatory to reduce PBVC variability.
Keywords
Brain, Volumetry, Variability, Icometrix, Real-world, MRI, ATROPHY, MS, QUANTIFICATION, RELIABILITY, PROGRESSION, ACCURATE, SCANNER

Downloads

  • Download
    publisher version.pdf
    • full text (Published version)
    • |
    • open access
    • |
    • PDF
    • |
    • 2.07 MB

Citation

Please use this url to cite or link to this publication:

MLA
Nguyen, Ai-Lan, et al. “Utility of Icobrain for Brain Volumetry in Multiple Sclerosis Clinical Practice.” MULTIPLE SCLEROSIS AND RELATED DISORDERS, vol. 92, 2024, doi:10.1016/j.msard.2024.106148.
APA
Nguyen, A.-L., Sormani, M. P., Horakova, D., Havrdova, E. H., Barnett, M. H., De Stefano, N., … Butzkueven, H. (2024). Utility of icobrain for brain volumetry in multiple sclerosis clinical practice. MULTIPLE SCLEROSIS AND RELATED DISORDERS, 92. https://doi.org/10.1016/j.msard.2024.106148
Chicago author-date
Nguyen, Ai-Lan, Maria Pia Sormani, Dana Horakova, Eva H Havrdova, Michael H Barnett, Nicola De Stefano, Marco Battaglini, et al. 2024. “Utility of Icobrain for Brain Volumetry in Multiple Sclerosis Clinical Practice.” MULTIPLE SCLEROSIS AND RELATED DISORDERS 92. https://doi.org/10.1016/j.msard.2024.106148.
Chicago author-date (all authors)
Nguyen, Ai-Lan, Maria Pia Sormani, Dana Horakova, Eva H Havrdova, Michael H Barnett, Nicola De Stefano, Marco Battaglini, Manuela Vaneckova, Elaine Lui, Frank Gaillard, Patricia M Desmond, Hayden Prime, Mineesh Datta, Anneke Van der Walt, Vilija G Jokubaitis, Femke Podevyn, Robert Zivadinov, Bianca Weinstock-Guttman, Marie B D’hooghe, Guy Nagels, Vincent Van Pesch, Guy Laureys, Liesbeth Van Hijfte, Jeannette Lechner-Scott, Francesco Patti, Edgardo Cristiano, Juan I Rojas, Diana M Sima, Wim Van Hecke, Tomas Kalincik, and Helmut Butzkueven. 2024. “Utility of Icobrain for Brain Volumetry in Multiple Sclerosis Clinical Practice.” MULTIPLE SCLEROSIS AND RELATED DISORDERS 92. doi:10.1016/j.msard.2024.106148.
Vancouver
1.
Nguyen A-L, Sormani MP, Horakova D, Havrdova EH, Barnett MH, De Stefano N, et al. Utility of icobrain for brain volumetry in multiple sclerosis clinical practice. MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2024;92.
IEEE
[1]
A.-L. Nguyen et al., “Utility of icobrain for brain volumetry in multiple sclerosis clinical practice,” MULTIPLE SCLEROSIS AND RELATED DISORDERS, vol. 92, 2024.
@article{01JCWV6D5QXQZS1MDPPTBDWAH1,
  abstract     = {{Background
Few studies on multiple sclerosis (MS) have explored the variability of percentage brain volume change (PBVC) measurements obtained from different clinical MRIs. In a retrospective multicentre cohort study, we quantified the variability of annualised PBVC in clinical MRIs.
Methods
Clinical MRIs of relapse-onset MS patients were assessed by icobrain. Volumetric data were analysed on same-scanner and different-scanner MRI pairs if they passed quality control criteria. Alignment similarity between two images had to be comparable to same-scanner scan-rescan images.
Results
Of 6826 MRIs, 85 % had appropriate volumetric sequences and 4446 serial MRI pairs were analysed. 3334 (75 %) MRI pairs from 1207 patients met the inclusions. The PBVC of included MRI pairs showed variance of 0.78 % for same-scanner pairs and 0.80 % for different-scanner pairs. Further selection of included MRI pairs with the best variance resulted in 1885 (42 %) MRI pairs with PBVC variance of 0.34 %. Excluded MRI pairs with poor alignment similarity had variances of 2.97 % for same-scanner pairs and 20.79 % for different-scanner pairs.
Conclusion
Icobrain should be utilised for PBVC determination only on selected MRIs with the best alignment similarity. Applying strict selection criteria for the included MRI pairs and longitudinal imaging on the same scanner remain mandatory to reduce PBVC variability.}},
  articleno    = {{106148}},
  author       = {{Nguyen, Ai-Lan and Sormani, Maria Pia and Horakova, Dana and Havrdova, Eva H and Barnett, Michael H and De Stefano, Nicola and Battaglini, Marco and Vaneckova, Manuela and Lui, Elaine and Gaillard, Frank and Desmond, Patricia M and Prime, Hayden and Datta, Mineesh and Van der Walt, Anneke and Jokubaitis, Vilija G and Podevyn, Femke and Zivadinov, Robert and Weinstock-Guttman, Bianca and D'hooghe, Marie B and Nagels, Guy and Van Pesch, Vincent and Laureys, Guy and Van Hijfte, Liesbeth and Lechner-Scott, Jeannette and Patti, Francesco and Cristiano, Edgardo and Rojas, Juan I and Sima, Diana M and Van Hecke, Wim and Kalincik, Tomas and Butzkueven, Helmut}},
  issn         = {{2211-0348}},
  journal      = {{MULTIPLE SCLEROSIS AND RELATED DISORDERS}},
  keywords     = {{Brain,Volumetry,Variability,Icometrix,Real-world,MRI,ATROPHY,MS,QUANTIFICATION,RELIABILITY,PROGRESSION,ACCURATE,SCANNER}},
  language     = {{eng}},
  pages        = {{10}},
  title        = {{Utility of icobrain for brain volumetry in multiple sclerosis clinical practice}},
  url          = {{http://doi.org/10.1016/j.msard.2024.106148}},
  volume       = {{92}},
  year         = {{2024}},
}
Altmetric
View in Altmetric
Web of Science
Times cited: