Concentric-object and equiangular-object methods to perform standardized regional analysis in renal mpMRI
- Author
- Luis Carlos Sanmiguel Serpa (UGent) , Pieter De Visschere (UGent) and Pim Pullens (UGent)
- Organization
- Abstract
- ObjectiveRenal multiparametric magnetic resonance imaging (mpMRI) sequences, including T1-T2 mapping, Blood oxygenation level-dependent (BOLD), Renal blood flow (RBF), and Apparent Diffusion Coefficient (ADC) from diffusion-weighted imaging (DWI), provide insights into kidney function. However, consensus on selecting regions of interest (ROIs) is lacking. This study aims to describe and compare the Concentric Objects (CO) and Equiangular Objects (EO) methods for standardized ROI selection and assess their efficacy in capturing regional variations in renal MRI parameters.Materials and methodsTwelve healthy volunteers underwent mpMRI renal scans. ROIs were selected manually and by applying the CO and EO algorithms to each mpMRI sequence. The methods were tested across various subregion configurations. Regional differences in renal MRI parameters were evaluated.ResultsCO and EO methods demonstrated statistically significant differences in mpMRI parameters across renal regions. ASL-RBF, BOLD-MRI, and T2-map results indicated substantial variations from the lower to upper kidney areas.DiscussionThis study implemented CO and EO algorithms in renal mpMRI, showing their potential for evaluating cortico-medullary and cranio-caudal profiles. The findings validate the CO method for BOLD and ADC measurements and presented ASL-RBF and T1-T2 map profiles. The EO method's utility needs further validation with renal patients.
- Keywords
- Kidney, Perfusion, Oxygenation, Diffusion, Multiparametric, MRI, T1 map, T2 map, HEALTHY-VOLUNTEERS, RELAXATION-TIMES, BOLD-MRI, OXYGENATION, KIDNEYS, REPRODUCIBILITY, PERFUSION
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-01JB9SYT8CWQTSVMWDK9QBKRQ1
- MLA
- Sanmiguel Serpa, Luis Carlos, et al. “Concentric-Object and Equiangular-Object Methods to Perform Standardized Regional Analysis in Renal MpMRI.” MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE, vol. 38, 2025, pp. 67–83, doi:10.1007/s10334-024-01208-0.
- APA
- Sanmiguel Serpa, L. C., De Visschere, P., & Pullens, P. (2025). Concentric-object and equiangular-object methods to perform standardized regional analysis in renal mpMRI. MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE, 38, 67–83. https://doi.org/10.1007/s10334-024-01208-0
- Chicago author-date
- Sanmiguel Serpa, Luis Carlos, Pieter De Visschere, and Pim Pullens. 2025. “Concentric-Object and Equiangular-Object Methods to Perform Standardized Regional Analysis in Renal MpMRI.” MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE 38: 67–83. https://doi.org/10.1007/s10334-024-01208-0.
- Chicago author-date (all authors)
- Sanmiguel Serpa, Luis Carlos, Pieter De Visschere, and Pim Pullens. 2025. “Concentric-Object and Equiangular-Object Methods to Perform Standardized Regional Analysis in Renal MpMRI.” MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE 38: 67–83. doi:10.1007/s10334-024-01208-0.
- Vancouver
- 1.Sanmiguel Serpa LC, De Visschere P, Pullens P. Concentric-object and equiangular-object methods to perform standardized regional analysis in renal mpMRI. MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE. 2025;38:67–83.
- IEEE
- [1]L. C. Sanmiguel Serpa, P. De Visschere, and P. Pullens, “Concentric-object and equiangular-object methods to perform standardized regional analysis in renal mpMRI,” MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE, vol. 38, pp. 67–83, 2025.
@article{01JB9SYT8CWQTSVMWDK9QBKRQ1,
abstract = {{ObjectiveRenal multiparametric magnetic resonance imaging (mpMRI) sequences, including T1-T2 mapping, Blood oxygenation level-dependent (BOLD), Renal blood flow (RBF), and Apparent Diffusion Coefficient (ADC) from diffusion-weighted imaging (DWI), provide insights into kidney function. However, consensus on selecting regions of interest (ROIs) is lacking. This study aims to describe and compare the Concentric Objects (CO) and Equiangular Objects (EO) methods for standardized ROI selection and assess their efficacy in capturing regional variations in renal MRI parameters.Materials and methodsTwelve healthy volunteers underwent mpMRI renal scans. ROIs were selected manually and by applying the CO and EO algorithms to each mpMRI sequence. The methods were tested across various subregion configurations. Regional differences in renal MRI parameters were evaluated.ResultsCO and EO methods demonstrated statistically significant differences in mpMRI parameters across renal regions. ASL-RBF, BOLD-MRI, and T2-map results indicated substantial variations from the lower to upper kidney areas.DiscussionThis study implemented CO and EO algorithms in renal mpMRI, showing their potential for evaluating cortico-medullary and cranio-caudal profiles. The findings validate the CO method for BOLD and ADC measurements and presented ASL-RBF and T1-T2 map profiles. The EO method's utility needs further validation with renal patients.}},
author = {{Sanmiguel Serpa, Luis Carlos and De Visschere, Pieter and Pullens, Pim}},
issn = {{1352-8661}},
journal = {{MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE}},
keywords = {{Kidney,Perfusion,Oxygenation,Diffusion,Multiparametric,MRI,T1 map,T2 map,HEALTHY-VOLUNTEERS,RELAXATION-TIMES,BOLD-MRI,OXYGENATION,KIDNEYS,REPRODUCIBILITY,PERFUSION}},
language = {{eng}},
pages = {{67--83}},
title = {{Concentric-object and equiangular-object methods to perform standardized regional analysis in renal mpMRI}},
url = {{http://doi.org/10.1007/s10334-024-01208-0}},
volume = {{38}},
year = {{2025}},
}
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