Academic Bibliography

 Search 200 years of publications by Ghent University researchers.
Advanced search
2 files | 1.53 MB
Add to list
  1. Search results
  2. Aflatoxins and fumonisins co-contamin...

Aflatoxins and fumonisins co-contamination effects on laying hens and use of mycotoxin detoxifiers as a mitigation strategy

Phillis Emelda Ochieng (UGent) , David Kemboi, Sheila Okoth, Siegrid De Baere (UGent) , Etienne Cavalier, Erastus Kang’ethe, Barbara Doupovec, James Gathumbi, Marie-Louise Scippo, Gunther Antonissen (UGent) , et al.
(2025) MYCOTOXIN RESEARCH. 41. p.63-75
Author
Organization
Project
Abstract
This study examined the effects of fumonisins (FBs) and aflatoxin B1 (AFB1), alone or in combination, on the productivity and health of laying hens, as well as the transfer of aflatoxins (AFs) to chicken food products. The efficacy and safety of mycotoxin detoxifiers (bentonite and fumonisin esterase) to mitigate these effects were also assessed. Laying hens (400) were divided into 20 groups and fed a control, moderate (54.6 mu g/kg feed) or high (546 mu g/kg feed) AFB1 or FBs (7.9 mg/kg feed) added diets, either alone or in combination, with the mycotoxin detoxifiers added in selected diets. Productivity was evaluated by feed intake, egg weight, egg production, and feed conversion ratio whereas health was assessed by organ weights, blood biochemistry, and mortality. Aflatoxins residues in plasma, liver, muscle, and eggs were determined using UHPLC-MS/MS methods. A diet with AFB1 at a concentration of 546 mu g/kg feed decreased egg production and various AFB1-contaminated diets increased serum uric acid levels and weights of liver, spleen, heart, and gizzard. Interactions between AFB1 and FBs significantly impacted spleen, heart, and gizzard weights as well as AFB1 residues in eggs. Maximum AFB1 residues of 0.64 mu g/kg and aflatoxin M1 (below limits of quantification) were observed in liver, plasma, and eggs of layers fed diets with AFB1. The mycotoxin detoxifiers reduced effects of AFB1 and FBs on egg production, organ weights, blood biochemistry, and AFB1 residues in tissues. This study highlights the importance of mycotoxin detoxifiers as a mitigation strategy against mycotoxins in poultry production.
Keywords
mycotoxins, poultry, sub-Saharan Africa, food safety, mycotoxin detoxifiers, Aflatoxins, Bentonite, Egg, Food and feed safety, Fumonisins, Kenya, Laying hen, FUSARIUM MYCOTOXINS, BROILER-CHICKENS, BIOCHEMICAL PARAMETERS, GASTROINTESTINAL-TRACT, BENTONITE CLAY, EGG QUALITY, FEED, B-1, PERFORMANCE, RESIDUES

Downloads

  • Download
    s12550-024-00566-x.pdf
    • full text (Published version)
    • |
    • open access
    • |
    • PDF
    • |
    • 774.99 KB
  • Download
    s12550-024-00566-x.pdf
    • full text (Published version)
    • |
    • open access
    • |
    • PDF
    • |
    • 756.54 KB

Citation

Please use this url to cite or link to this publication:

MLA
Ochieng, Phillis Emelda, et al. “Aflatoxins and Fumonisins Co-Contamination Effects on Laying Hens and Use of Mycotoxin Detoxifiers as a Mitigation Strategy.” MYCOTOXIN RESEARCH, vol. 41, 2025, pp. 63–75, doi:10.1007/s12550-024-00566-x.
APA
Ochieng, P. E., Kemboi, D., Okoth, S., De Baere, S., Cavalier, E., Kang’ethe, E., … Croubels, S. (2025). Aflatoxins and fumonisins co-contamination effects on laying hens and use of mycotoxin detoxifiers as a mitigation strategy. MYCOTOXIN RESEARCH, 41, 63–75. https://doi.org/10.1007/s12550-024-00566-x
Chicago author-date
Ochieng, Phillis Emelda, David Kemboi, Sheila Okoth, Siegrid De Baere, Etienne Cavalier, Erastus Kang’ethe, Barbara Doupovec, et al. 2025. “Aflatoxins and Fumonisins Co-Contamination Effects on Laying Hens and Use of Mycotoxin Detoxifiers as a Mitigation Strategy.” MYCOTOXIN RESEARCH 41: 63–75. https://doi.org/10.1007/s12550-024-00566-x.
Chicago author-date (all authors)
Ochieng, Phillis Emelda, David Kemboi, Sheila Okoth, Siegrid De Baere, Etienne Cavalier, Erastus Kang’ethe, Barbara Doupovec, James Gathumbi, Marie-Louise Scippo, Gunther Antonissen, Johanna F. Lindahl, and Siska Croubels. 2025. “Aflatoxins and Fumonisins Co-Contamination Effects on Laying Hens and Use of Mycotoxin Detoxifiers as a Mitigation Strategy.” MYCOTOXIN RESEARCH 41: 63–75. doi:10.1007/s12550-024-00566-x.
Vancouver
1.
Ochieng PE, Kemboi D, Okoth S, De Baere S, Cavalier E, Kang’ethe E, et al. Aflatoxins and fumonisins co-contamination effects on laying hens and use of mycotoxin detoxifiers as a mitigation strategy. MYCOTOXIN RESEARCH. 2025;41:63–75.
IEEE
[1]
P. E. Ochieng et al., “Aflatoxins and fumonisins co-contamination effects on laying hens and use of mycotoxin detoxifiers as a mitigation strategy,” MYCOTOXIN RESEARCH, vol. 41, pp. 63–75, 2025.
@article{01JA7QW6906D36GSJJ9ZT5FWTE,
  abstract     = {{This study examined the effects of fumonisins (FBs) and aflatoxin B1 (AFB1), alone or in combination, on the productivity and health of laying hens, as well as the transfer of aflatoxins (AFs) to chicken food products. The efficacy and safety of mycotoxin detoxifiers (bentonite and fumonisin esterase) to mitigate these effects were also assessed. Laying hens (400) were divided into 20 groups and fed a control, moderate (54.6 mu g/kg feed) or high (546 mu g/kg feed) AFB1 or FBs (7.9 mg/kg feed) added diets, either alone or in combination, with the mycotoxin detoxifiers added in selected diets. Productivity was evaluated by feed intake, egg weight, egg production, and feed conversion ratio whereas health was assessed by organ weights, blood biochemistry, and mortality. Aflatoxins residues in plasma, liver, muscle, and eggs were determined using UHPLC-MS/MS methods. A diet with AFB1 at a concentration of 546 mu g/kg feed decreased egg production and various AFB1-contaminated diets increased serum uric acid levels and weights of liver, spleen, heart, and gizzard. Interactions between AFB1 and FBs significantly impacted spleen, heart, and gizzard weights as well as AFB1 residues in eggs. Maximum AFB1 residues of 0.64 mu g/kg and aflatoxin M1 (below limits of quantification) were observed in liver, plasma, and eggs of layers fed diets with AFB1. The mycotoxin detoxifiers reduced effects of AFB1 and FBs on egg production, organ weights, blood biochemistry, and AFB1 residues in tissues. This study highlights the importance of mycotoxin detoxifiers as a mitigation strategy against mycotoxins in poultry production.}},
  author       = {{Ochieng, Phillis Emelda and Kemboi, David and Okoth, Sheila and De Baere, Siegrid and Cavalier, Etienne and Kang’ethe, Erastus and Doupovec, Barbara and Gathumbi, James and Scippo, Marie-Louise and Antonissen, Gunther and Lindahl, Johanna F. and Croubels, Siska}},
  issn         = {{0178-7888}},
  journal      = {{MYCOTOXIN RESEARCH}},
  keywords     = {{mycotoxins,poultry,sub-Saharan Africa,food safety,mycotoxin detoxifiers,Aflatoxins,Bentonite,Egg,Food and feed safety,Fumonisins,Kenya,Laying hen,FUSARIUM MYCOTOXINS,BROILER-CHICKENS,BIOCHEMICAL PARAMETERS,GASTROINTESTINAL-TRACT,BENTONITE CLAY,EGG QUALITY,FEED,B-1,PERFORMANCE,RESIDUES}},
  language     = {{eng}},
  pages        = {{63--75}},
  title        = {{Aflatoxins and fumonisins co-contamination effects on laying hens and use of mycotoxin detoxifiers as a mitigation strategy}},
  url          = {{http://doi.org/10.1007/s12550-024-00566-x}},
  volume       = {{41}},
  year         = {{2025}},
}
Altmetric
View in Altmetric
Web of Science
Times cited: