Bacillus lipopeptides as key players in rhizosphere chemical ecology
- Author
- Guillaume Balleux, Monica Höfte (UGent) , Anthony Arguelles-Arias, Magali Deleu and Marc Ongena
- Organization
- Abstract
- Microbial natural products are widely explored for their therapeutic potential. Understanding the underlying evolutionary and adaptive forces driving their production remains a fundamental question in biology. Amphiphilic cyclic lipopeptides (CLPs), a prominent category of bacterial specialized metabolites, show strong antimicrobial activity, particularly against phytopathogens. It is thus assumed that these compounds are deployed by soil- or rhizosphere-dwelling bacteria as microbial weapons in competitive natural environments. Here, we challenge this reductionist perspective and present evidence that Bacillus CLPs are prominent chemical mediators of ecological interactions. They help Bacillus to communicate, compete, defend against predators, or cooperate and establish mutualistic relationships with other (micro)organisms. Additional parallel examples are highlighted in other genera, such as Pseudomonas. This broader perspective underscores the need for further investigation into the role of CLPs in shaping the adaptive strategies of key rhizobacterial species.
- Keywords
- ANTIMICROBIAL LIPOPEPTIDES, NONRIBOSOMAL LIPOPEPTIDES, PSEUDOMONAS-SYRINGAE, SYSTEMIC RESISTANCE, BIOFILM FORMATION, BACILLOMYCIN-D, SUBTILIS, SURFACTIN, BIOCONTROL, MEMBRANE
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-01J6PSX3DN0T3YE6DZ4FEHTNRC
- MLA
- Balleux, Guillaume, et al. “Bacillus Lipopeptides as Key Players in Rhizosphere Chemical Ecology.” TRENDS IN MICROBIOLOGY, vol. 33, no. 1, 2025, pp. 80–95, doi:10.1016/j.tim.2024.08.001.
- APA
- Balleux, G., Höfte, M., Arguelles-Arias, A., Deleu, M., & Ongena, M. (2025). Bacillus lipopeptides as key players in rhizosphere chemical ecology. TRENDS IN MICROBIOLOGY, 33(1), 80–95. https://doi.org/10.1016/j.tim.2024.08.001
- Chicago author-date
- Balleux, Guillaume, Monica Höfte, Anthony Arguelles-Arias, Magali Deleu, and Marc Ongena. 2025. “Bacillus Lipopeptides as Key Players in Rhizosphere Chemical Ecology.” TRENDS IN MICROBIOLOGY 33 (1): 80–95. https://doi.org/10.1016/j.tim.2024.08.001.
- Chicago author-date (all authors)
- Balleux, Guillaume, Monica Höfte, Anthony Arguelles-Arias, Magali Deleu, and Marc Ongena. 2025. “Bacillus Lipopeptides as Key Players in Rhizosphere Chemical Ecology.” TRENDS IN MICROBIOLOGY 33 (1): 80–95. doi:10.1016/j.tim.2024.08.001.
- Vancouver
- 1.Balleux G, Höfte M, Arguelles-Arias A, Deleu M, Ongena M. Bacillus lipopeptides as key players in rhizosphere chemical ecology. TRENDS IN MICROBIOLOGY. 2025;33(1):80–95.
- IEEE
- [1]G. Balleux, M. Höfte, A. Arguelles-Arias, M. Deleu, and M. Ongena, “Bacillus lipopeptides as key players in rhizosphere chemical ecology,” TRENDS IN MICROBIOLOGY, vol. 33, no. 1, pp. 80–95, 2025.
@article{01J6PSX3DN0T3YE6DZ4FEHTNRC,
abstract = {{Microbial natural products are widely explored for their therapeutic potential. Understanding the underlying evolutionary and adaptive forces driving their production remains a fundamental question in biology. Amphiphilic cyclic lipopeptides (CLPs), a prominent category of bacterial specialized metabolites, show strong antimicrobial activity, particularly against phytopathogens. It is thus assumed that these compounds are deployed by soil- or rhizosphere-dwelling bacteria as microbial weapons in competitive natural environments. Here, we challenge this reductionist perspective and present evidence that Bacillus CLPs are prominent chemical mediators of ecological interactions. They help Bacillus to communicate, compete, defend against predators, or cooperate and establish mutualistic relationships with other (micro)organisms. Additional parallel examples are highlighted in other genera, such as Pseudomonas. This broader perspective underscores the need for further investigation into the role of CLPs in shaping the adaptive strategies of key rhizobacterial species.}},
author = {{Balleux, Guillaume and Höfte, Monica and Arguelles-Arias, Anthony and Deleu, Magali and Ongena, Marc}},
issn = {{0966-842X}},
journal = {{TRENDS IN MICROBIOLOGY}},
keywords = {{ANTIMICROBIAL LIPOPEPTIDES,NONRIBOSOMAL LIPOPEPTIDES,PSEUDOMONAS-SYRINGAE,SYSTEMIC RESISTANCE,BIOFILM FORMATION,BACILLOMYCIN-D,SUBTILIS,SURFACTIN,BIOCONTROL,MEMBRANE}},
language = {{eng}},
number = {{1}},
pages = {{80--95}},
title = {{Bacillus lipopeptides as key players in rhizosphere chemical ecology}},
url = {{http://doi.org/10.1016/j.tim.2024.08.001}},
volume = {{33}},
year = {{2025}},
}
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