@article{01J6PMKN4MNDFAEPCNZNV0DM1D,
  abstract     = {{Background Sebaceous adenitis (SA) is an immune-mediated disease targeting the sebaceous glands. Meibomian gland dysfunction is a disease affecting meibomian glands with inflammatory features. Sebaceous and meibomian glands share anatomical, physiological and embryological similarities. The involvement of meibomian glands in dogs with SA is currently unknown. Objectives To evaluate meibomian glands in dogs affected by SA and compare them with healthy dogs. Animals Eighteen dogs were enrolled. Nine dogs with SA were retrospectively identified from clinical records and represented the case group. Nine healthy, breed- and age-matched dogs were prospectively enrolled in the control group. Materials and Methods Both groups underwent dermatological examination, Schirmer tear test-1 (STT-1), tear meniscus height (TMH), slit-lamp biomicroscopy, interferometry (INT) and noncontact infrared meibography (NIM). Results One third of SA dogs presented subepithelial crystalline opacities. No significant difference between groups was observed in TMH (p = 0.944) and STT-1 values (p = 0.066). INT (p = 0.016) and NIM grades (p = 0.010) were significantly higher and lower in the SA group compared to the control group, respectively. INT values decreased with age (eta = 0.930), while NIM scores (eta = 0.935) increased. Conclusions Clinical Relevance: Subepithelial crystalline opacities in SA dogs might reflect a reduced tear film quality. In the absence of standardised methods, INT and NIM proved to be noninvasive and useful methods to examine meibomian glands. Dogs with SA showed a thinner lacrimal lipid layer and more severe meibomian gland abnormalities than control dogs, which seemed to progress with age.}},
  author       = {{Striuli, Giulia and Vandenabeele, Sophie and Nachtegaele, Filip and Devriendt, Nausikaa}},
  issn         = {{0959-4493}},
  journal      = {{VETERINARY DERMATOLOGY}},
  keywords     = {{canine,interferometry,meibography,meibomian gland dysfunction,sebaceous glands,INTERNATIONAL WORKSHOP,OCULAR SURFACE,CYCLOSPORINE-A,DRY EYE,HISTOPATHOLOGY,CLASSIFICATION,SUBCOMMITTEE}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{605--616}},
  title        = {{Correlation between meibomian gland dysfunction and sebaceous adenitis in dogs}},
  url          = {{http://doi.org/10.1111/vde.13293}},
  volume       = {{35}},
  year         = {{2024}},
}

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