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Screening for early feline chronic kidney disease : diagnostic aspects and clinical importance of borderline proteinuria in cats

Femke Mortier (UGent)
(2024)
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Abstract
Chapter 1 provides general information about chronic kidney disease (CKD), a common condition in cats. This disease is mostly diagnosed late in the disease course, when measures to slow progression of disease provide less benefit compared to earlier intervention. Early detection of CKD is however difficult since diagnosis is usually based on renal azotemia, which occurs only after a substantial amount of renal function loss has occurred. Measuring the urinary protein: creatinine ratio (UPC) is important to diagnose and monitor CKD and determine the need for directed therapy, since proteinuria decreases survival time in cats with CKD. According to International Renal Interest Society (IRIS) guidelines, persistent renal proteinuria (UPC >0.4) or inadequate urine concentrating ability (urine specific gravity [USG] <1.035) could indicate the presence of CKD even in non-azotemic cats (IRIS stage 1 or early stage 2 CKD).

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Citation

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MLA
Mortier, Femke. Screening for Early Feline Chronic Kidney Disease : Diagnostic Aspects and Clinical Importance of Borderline Proteinuria in Cats. Ghent University. Faculty of Veterinary Medicine, 2024.
APA
Mortier, F. (2024). Screening for early feline chronic kidney disease : diagnostic aspects and clinical importance of borderline proteinuria in cats. Ghent University. Faculty of Veterinary Medicine, Merelbeke, Belgium.
Chicago author-date
Mortier, Femke. 2024. “Screening for Early Feline Chronic Kidney Disease : Diagnostic Aspects and Clinical Importance of Borderline Proteinuria in Cats.” Merelbeke, Belgium: Ghent University. Faculty of Veterinary Medicine.
Chicago author-date (all authors)
Mortier, Femke. 2024. “Screening for Early Feline Chronic Kidney Disease : Diagnostic Aspects and Clinical Importance of Borderline Proteinuria in Cats.” Merelbeke, Belgium: Ghent University. Faculty of Veterinary Medicine.
Vancouver
1.
Mortier F. Screening for early feline chronic kidney disease : diagnostic aspects and clinical importance of borderline proteinuria in cats. [Merelbeke, Belgium]: Ghent University. Faculty of Veterinary Medicine; 2024.
IEEE
[1]
F. Mortier, “Screening for early feline chronic kidney disease : diagnostic aspects and clinical importance of borderline proteinuria in cats,” Ghent University. Faculty of Veterinary Medicine, Merelbeke, Belgium, 2024.
@phdthesis{01J6HC5W44NQ4661P7J9PXV7W7,
  abstract     = {{Chapter 1 provides general information about chronic kidney disease (CKD), a common condition in cats. This disease is mostly diagnosed late in the disease course, when measures to slow progression of disease provide less benefit compared to earlier intervention. Early detection of CKD is however difficult since diagnosis is usually based on renal azotemia, which occurs only after a substantial amount of renal function loss has occurred. Measuring the urinary protein: creatinine ratio (UPC) is important to diagnose and monitor CKD and determine the need for directed therapy, since proteinuria decreases survival time in cats with CKD. According to International Renal Interest Society (IRIS) guidelines, persistent renal proteinuria (UPC >0.4) or inadequate urine concentrating ability (urine specific gravity [USG] <1.035) could indicate the presence of CKD even in non-azotemic cats (IRIS stage 1 or early stage 2 CKD).}},
  author       = {{Mortier, Femke}},
  language     = {{eng}},
  pages        = {{VIII, 289}},
  publisher    = {{Ghent University. Faculty of Veterinary Medicine}},
  school       = {{Ghent University}},
  title        = {{Screening for early feline chronic kidney disease : diagnostic aspects and clinical importance of borderline proteinuria in cats}},
  year         = {{2024}},
}