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Anticipatory gaps challenge the public governance of heritable human genome editing

(2025) JOURNAL OF MEDICAL ETHICS. 51(5). p.317-321
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Abstract
Considering public moral attitudes is a hallmark of the anticipatory governance of emerging biotechnologies, such as heritable human genome editing. However, such anticipatory governance often overlooks that future morality is open to change and that future generations may perform different moral assessments on the very biotechnologies we are trying to govern in the present. In this article, we identify an ‘anticipatory gap’ that has not been sufficiently addressed in the discussion on the public governance of heritable genome editing, namely, uncertainty about the moral visions of future generations about the emerging applications that we are currently attempting to govern now. This paper motivates the relevance of this anticipatory gap, identifying the challenges it generates and offering various recommendations so that moral uncertainty does not lead to governance paralysis with regard to human germline genome editing.
Keywords
Genetic Enhancement, Genetic Engineering, Public Policy, Ethics, Morals, ENGAGEMENT, ATTITUDES, FUTURE, LIMITS, VIEWS, NEED

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MLA
Rueda, Jon, et al. “Anticipatory Gaps Challenge the Public Governance of Heritable Human Genome Editing.” JOURNAL OF MEDICAL ETHICS, vol. 51, no. 5, 2025, pp. 317–21, doi:10.1136/jme-2023-109801.
APA
Rueda, J., Segers, S., Hopster, J., Kudlek, K., Liedo, B., Marchiori, S., & Danaher, J. (2025). Anticipatory gaps challenge the public governance of heritable human genome editing. JOURNAL OF MEDICAL ETHICS, 51(5), 317–321. https://doi.org/10.1136/jme-2023-109801
Chicago author-date
Rueda, Jon, Seppe Segers, Jeroen Hopster, Karolina Kudlek, Belén Liedo, Samuela Marchiori, and John Danaher. 2025. “Anticipatory Gaps Challenge the Public Governance of Heritable Human Genome Editing.” JOURNAL OF MEDICAL ETHICS 51 (5): 317–21. https://doi.org/10.1136/jme-2023-109801.
Chicago author-date (all authors)
Rueda, Jon, Seppe Segers, Jeroen Hopster, Karolina Kudlek, Belén Liedo, Samuela Marchiori, and John Danaher. 2025. “Anticipatory Gaps Challenge the Public Governance of Heritable Human Genome Editing.” JOURNAL OF MEDICAL ETHICS 51 (5): 317–321. doi:10.1136/jme-2023-109801.
Vancouver
1.
Rueda J, Segers S, Hopster J, Kudlek K, Liedo B, Marchiori S, et al. Anticipatory gaps challenge the public governance of heritable human genome editing. JOURNAL OF MEDICAL ETHICS. 2025;51(5):317–21.
IEEE
[1]
J. Rueda et al., “Anticipatory gaps challenge the public governance of heritable human genome editing,” JOURNAL OF MEDICAL ETHICS, vol. 51, no. 5, pp. 317–321, 2025.
@article{01J6H3STN89R4W3FM9EW0TFDMJ,
  abstract     = {{Considering public moral attitudes is a hallmark of the anticipatory governance of emerging biotechnologies, such as heritable human genome editing. However, such anticipatory governance often overlooks that future morality is open to change and that future generations may perform different moral assessments on the very biotechnologies we are trying to govern in the present. In this article, we identify an ‘anticipatory gap’ that has not been sufficiently addressed in the discussion on the public governance of heritable genome editing, namely, uncertainty about the moral visions of future generations about the emerging applications that we are currently attempting to govern now. This paper motivates the relevance of this anticipatory gap, identifying the challenges it generates and offering various recommendations so that moral uncertainty does not lead to governance paralysis with regard to human germline genome editing.}},
  author       = {{Rueda, Jon and Segers, Seppe and Hopster, Jeroen and Kudlek, Karolina and Liedo, Belén and Marchiori, Samuela and Danaher, John}},
  issn         = {{0306-6800}},
  journal      = {{JOURNAL OF MEDICAL ETHICS}},
  keywords     = {{Genetic Enhancement,Genetic Engineering,Public Policy,Ethics,Morals,ENGAGEMENT,ATTITUDES,FUTURE,LIMITS,VIEWS,NEED}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{317--321}},
  title        = {{Anticipatory gaps challenge the public governance of heritable human genome editing}},
  url          = {{http://doi.org/10.1136/jme-2023-109801}},
  volume       = {{51}},
  year         = {{2025}},
}

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