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Applicability of STOPP/START prescribing criteria in integrated Swedish administrative health registries and a Swedish population-based cohort

(2024) EUROPEAN GERIATRIC MEDICINE. 15. p.1149-1158
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Abstract
Purpose: The STOPP/START criteria are frequently applied in observational studies to assess potentially inappropriate prescribing in older adults. This study aimed to assess the applicability of the three available STOPP/START versions in two distinct data sources. Methods: To evaluate the applicability of the three versions of STOPP/START criteria, we used two observational data sources: (i) Integrated Swedish administrative health registries (ISHR) encompassing routinely collected health data and (ii) the population-based Swedish National study on Aging and Care in Kungsholmen (SNAC-K), based on health professional-led clinical assessments. The Anatomical Therapeutic Classification code (ATC) was used to categorise medications. Diseases were categorised using the international classification of diseases version 10 (ICD10). Results: The first STOPP/START version demonstrated an applicability rate of 80% in ISHR and 84% in SNAC-K. The second version demonstrated an applicability of 64% in ISHR and 74% in SNAC-K. The third version showed an applicability of 66% in ISHR and 77% in SNAC-K. Challenges in applicability included broad definitions, vague terminology, and the lack of information on disease severity, symptomatic traits, and stability of certain conditions. Conclusion: The applicability of the STOPP/START criteria in observational studies seems to have decreased in more recent versions of the tool. Population-based studies with comprehensive clinical assessments may offer higher applicability compared to studies based on administrative data. Future versions of the STOPP/START criteria should prioritise clear and unambiguous definitions to improve their applicability in research and promote result generalisability and comparability.
Keywords
STOPP/START, medication review, applicability of STOPP/START, automation of STOPP/START, screening tool

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MLA
Amrouch, Cheïma, et al. “Applicability of STOPP/START Prescribing Criteria in Integrated Swedish Administrative Health Registries and a Swedish Population-Based Cohort.” EUROPEAN GERIATRIC MEDICINE, vol. 15, 2024, pp. 1149–58, doi:10.1007/s41999-024-00990-3.
APA
Amrouch, C., Amrouch, S., Dai, L., Calderón‑Larrañaga, A., Wastesson, J., Johnell, K., … Petrovic, M. (2024). Applicability of STOPP/START prescribing criteria in integrated Swedish administrative health registries and a Swedish population-based cohort. EUROPEAN GERIATRIC MEDICINE, 15, 1149–1158. https://doi.org/10.1007/s41999-024-00990-3
Chicago author-date
Amrouch, Cheïma, Souad Amrouch, Lu Dai, Amaia Calderón‑Larrañaga, Jonas Wastesson, Kristina Johnell, Davide Liborio Vetrano, Delphine De Smedt, and Mirko Petrovic. 2024. “Applicability of STOPP/START Prescribing Criteria in Integrated Swedish Administrative Health Registries and a Swedish Population-Based Cohort.” EUROPEAN GERIATRIC MEDICINE 15: 1149–58. https://doi.org/10.1007/s41999-024-00990-3.
Chicago author-date (all authors)
Amrouch, Cheïma, Souad Amrouch, Lu Dai, Amaia Calderón‑Larrañaga, Jonas Wastesson, Kristina Johnell, Davide Liborio Vetrano, Delphine De Smedt, and Mirko Petrovic. 2024. “Applicability of STOPP/START Prescribing Criteria in Integrated Swedish Administrative Health Registries and a Swedish Population-Based Cohort.” EUROPEAN GERIATRIC MEDICINE 15: 1149–1158. doi:10.1007/s41999-024-00990-3.
Vancouver
1.
Amrouch C, Amrouch S, Dai L, Calderón‑Larrañaga A, Wastesson J, Johnell K, et al. Applicability of STOPP/START prescribing criteria in integrated Swedish administrative health registries and a Swedish population-based cohort. EUROPEAN GERIATRIC MEDICINE. 2024;15:1149–58.
IEEE
[1]
C. Amrouch et al., “Applicability of STOPP/START prescribing criteria in integrated Swedish administrative health registries and a Swedish population-based cohort,” EUROPEAN GERIATRIC MEDICINE, vol. 15, pp. 1149–1158, 2024.
@article{01HY1HXARE0RTNVJVAHQ4PTB95,
  abstract     = {{Purpose: The STOPP/START criteria are frequently applied in observational studies to assess potentially inappropriate prescribing in older adults. This study aimed to assess the applicability of the three available STOPP/START versions in two distinct data sources. 
Methods: To evaluate the applicability of the three versions of STOPP/START criteria, we used two observational data sources: (i) Integrated Swedish administrative health registries (ISHR) encompassing routinely collected health data and (ii) the population-based Swedish National study on Aging and Care in Kungsholmen (SNAC-K), based on health professional-led clinical assessments. The Anatomical Therapeutic Classification code (ATC) was used to categorise medications. Diseases were categorised using the international classification of diseases version 10 (ICD10).	
Results: The first STOPP/START version demonstrated an applicability rate of 80% in ISHR and 84% in SNAC-K. The second version demonstrated an applicability of 64% in ISHR and 74% in SNAC-K. The third version showed an applicability of 66% in ISHR and 77% in SNAC-K. Challenges in applicability included broad definitions, vague terminology, and the lack of information on disease severity, symptomatic traits, and stability of certain conditions.
Conclusion: The applicability of the STOPP/START criteria in observational studies seems to have decreased in more recent versions of the tool. Population-based studies with comprehensive clinical assessments may offer higher applicability compared to studies based on administrative data. Future versions of the STOPP/START criteria should prioritise clear and unambiguous definitions to improve their applicability in research and promote result generalisability and comparability.}},
  author       = {{Amrouch, Cheïma and Amrouch, Souad and Dai, Lu and Calderón‑Larrañaga, Amaia and Wastesson, Jonas and Johnell, Kristina and Vetrano, Davide Liborio and De Smedt, Delphine and Petrovic, Mirko}},
  issn         = {{1878-7649}},
  journal      = {{EUROPEAN GERIATRIC MEDICINE}},
  keywords     = {{STOPP/START,medication review,applicability of STOPP/START,automation of STOPP/START,screening tool}},
  language     = {{eng}},
  pages        = {{1149--1158}},
  title        = {{Applicability of STOPP/START prescribing criteria in integrated Swedish administrative health registries and a Swedish population-based cohort}},
  url          = {{http://doi.org/10.1007/s41999-024-00990-3}},
  volume       = {{15}},
  year         = {{2024}},
}

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