Ratiometric dual-emitting thermometers based on rhodamine B dye-incorporated (nano) curcumin periodic mesoporous organosilicas for bioapplications
- Author
- Chunhui Liu (UGent) , Simona Premcheska (UGent) , Andre Skirtach (UGent) , Dirk Poelman (UGent) , Anna Kaczmarek (UGent) and Pascal Van Der Voort (UGent)
- Organization
- Project
- Abstract
- This study explores the potential of combining periodic mesoporous organosilicas (PMOs) with a fluorescent dye to develop a ratiometric thermometry system with enhanced stability, sensitivity, and biocompatibility. PMOs, ordered porous materials known for their stability and versatility, serve as an ideal platform. Curcumin, a natural polyphenol and fluorescent dye, is incorporated into PMOs to develop curcumin-functionalized PMOs (C-PMO) and curcumin-pyrazole-functionalized PMOs (CP-PMO) via hydrolysis and co-condensation. These PMOs exhibit temperature-dependent fluorescence properties. The next step involves encapsulating rhodamine B (RhB) dye within the PMO pores to create dual-emitting PMO@dye nanocomposites, followed by a lipid bilayer (LB) coating to enhance biocompatibility and dye retention. Remarkably, within the physiological temperature range, C-PMO@RhB@LB and CP-PMO@RhB@LB demonstrate noteworthy maximum relative sensitivity (Sr) values of up to 1.69 and 2.60% K-1, respectively. This approach offers versatile means to create various ratiometric thermometers by incorporating different fluorescent dyes, holding promise for future temperature sensing applications. This study explores the potential of combining periodic mesoporous organosilicas (PMOs) with a fluorescent dye to develop a ratiometric thermometry system with enhanced stability, sensitivity, and biocompatibility.
- Keywords
- ORGANIC GROUPS, NANOPARTICLES
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Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-01HVC71T904HG5N6VAMKBN458V
- MLA
- Liu, Chunhui, et al. “Ratiometric Dual-Emitting Thermometers Based on Rhodamine B Dye-Incorporated (Nano) Curcumin Periodic Mesoporous Organosilicas for Bioapplications.” JOURNAL OF MATERIALS CHEMISTRY C, vol. 12, no. 16, 2024, p. 5848, doi:10.1039/d3tc04416e.
- APA
- Liu, C., Premcheska, S., Skirtach, A., Poelman, D., Kaczmarek, A., & Van Der Voort, P. (2024). Ratiometric dual-emitting thermometers based on rhodamine B dye-incorporated (nano) curcumin periodic mesoporous organosilicas for bioapplications. JOURNAL OF MATERIALS CHEMISTRY C, 12(16), 5848. https://doi.org/10.1039/d3tc04416e
- Chicago author-date
- Liu, Chunhui, Simona Premcheska, Andre Skirtach, Dirk Poelman, Anna Kaczmarek, and Pascal Van Der Voort. 2024. “Ratiometric Dual-Emitting Thermometers Based on Rhodamine B Dye-Incorporated (Nano) Curcumin Periodic Mesoporous Organosilicas for Bioapplications.” JOURNAL OF MATERIALS CHEMISTRY C 12 (16): 5848. https://doi.org/10.1039/d3tc04416e.
- Chicago author-date (all authors)
- Liu, Chunhui, Simona Premcheska, Andre Skirtach, Dirk Poelman, Anna Kaczmarek, and Pascal Van Der Voort. 2024. “Ratiometric Dual-Emitting Thermometers Based on Rhodamine B Dye-Incorporated (Nano) Curcumin Periodic Mesoporous Organosilicas for Bioapplications.” JOURNAL OF MATERIALS CHEMISTRY C 12 (16): 5848. doi:10.1039/d3tc04416e.
- Vancouver
- 1.Liu C, Premcheska S, Skirtach A, Poelman D, Kaczmarek A, Van Der Voort P. Ratiometric dual-emitting thermometers based on rhodamine B dye-incorporated (nano) curcumin periodic mesoporous organosilicas for bioapplications. JOURNAL OF MATERIALS CHEMISTRY C. 2024;12(16):5848.
- IEEE
- [1]C. Liu, S. Premcheska, A. Skirtach, D. Poelman, A. Kaczmarek, and P. Van Der Voort, “Ratiometric dual-emitting thermometers based on rhodamine B dye-incorporated (nano) curcumin periodic mesoporous organosilicas for bioapplications,” JOURNAL OF MATERIALS CHEMISTRY C, vol. 12, no. 16, p. 5848, 2024.
@article{01HVC71T904HG5N6VAMKBN458V,
abstract = {{This study explores the potential of combining periodic mesoporous
organosilicas (PMOs) with a fluorescent dye to develop a ratiometric
thermometry system with enhanced stability, sensitivity, and
biocompatibility. PMOs, ordered porous materials known for their
stability and versatility, serve as an ideal platform. Curcumin, a
natural polyphenol and fluorescent dye, is incorporated into PMOs to
develop curcumin-functionalized PMOs (C-PMO) and
curcumin-pyrazole-functionalized PMOs (CP-PMO) via hydrolysis and
co-condensation. These PMOs exhibit temperature-dependent fluorescence
properties. The next step involves encapsulating rhodamine B (RhB) dye
within the PMO pores to create dual-emitting PMO@dye nanocomposites,
followed by a lipid bilayer (LB) coating to enhance biocompatibility and
dye retention. Remarkably, within the physiological temperature range,
C-PMO@RhB@LB and CP-PMO@RhB@LB demonstrate noteworthy maximum relative
sensitivity (Sr) values of up to 1.69 and 2.60% K-1, respectively. This
approach offers versatile means to create various ratiometric
thermometers by incorporating different fluorescent dyes, holding
promise for future temperature sensing applications.
This study explores the potential of combining periodic mesoporous
organosilicas (PMOs) with a fluorescent dye to develop a ratiometric
thermometry system with enhanced stability, sensitivity, and
biocompatibility.}},
author = {{Liu, Chunhui and Premcheska, Simona and Skirtach, Andre and Poelman, Dirk and Kaczmarek, Anna and Van Der Voort, Pascal}},
issn = {{2050-7526}},
journal = {{JOURNAL OF MATERIALS CHEMISTRY C}},
keywords = {{ORGANIC GROUPS,NANOPARTICLES}},
language = {{eng}},
number = {{16}},
title = {{Ratiometric dual-emitting thermometers based on rhodamine B dye-incorporated (nano) curcumin periodic mesoporous organosilicas for bioapplications}},
url = {{http://doi.org/10.1039/d3tc04416e}},
volume = {{12}},
year = {{2024}},
}
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