@article{01HV0ZC3R91R6PQ910M91Y0PTC,
  abstract     = {{Transcranial direct current stimulation (tDCS) targeting the prefrontal cortex has emerged as a valuable tool in psychiatric research. Understanding the impact of affective states, such as stress at the time of stimulation, on the efficacy of prefrontal tDCS is crucial for advancing tDCS interventions. Stress-primed tDCS, wherein stress is used as a priming agent, has the potential to modulate neural plasticity and enhance cognitive functions, particularly in emotional working memory. However, prior research using stress-primed tDCS focused solely on non-emotional working memory performance, yielding mixed results. In this sham-controlled study, we addressed this gap by investigating the effects of stress-primed bifrontal tDCS (active versus sham) on both non-emotional and emotional working memory performance. The study was conducted in 146 healthy individuals who were randomly assigned to four experimental groups. The Trier Social Stress Test (TSST) or a control variant of the test was used to induce a stress versus control state. The results showed that stress priming significantly enhanced the effects of tDCS on the updating of emotional content in working memory, as evidenced by improved accuracy. Notably, no significant effects of stress priming were found for non-emotional working memory performance. These findings highlight the importance of an individual's prior affective state in shaping their response to tDCS, especially in the context of emotional working memory.}},
  author       = {{De Smet, Stefanie and Boralli Razza, Laís and Pulópulos Tripiana, Matias Miguel and De Raedt, Rudi and Baeken, Chris and Brunoni, Andre R. and Vanderhasselt, Marie-Anne}},
  issn         = {{1935-861X}},
  journal      = {{BRAIN STIMULATION}},
  keywords     = {{Neurology (clinical),Biophysics,General Neuroscience,Emotional working memory,Stress priming,Affective state-dependency,Transcranial direct current stimulation (tDCS)}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{434--443}},
  title        = {{Stress priming transcranial direct current stimulation (tDCS) enhances updating of emotional content in working memory}},
  url          = {{http://doi.org/10.1016/j.brs.2024.03.021}},
  volume       = {{17}},
  year         = {{2024}},
}

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