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Imagistic findings using artificial intelligence in vaccinated versus unvaccinated SARS-CoV-2-positive patients receiving in-care treatment at a tertiary lung hospital

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Abstract
Background: In December 2019 the World Health Organization announced that the widespread severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection had become a global pandemic. The most affected organ by the novel virus is the lung, and imaging exploration of the thorax using computer tomography (CT) scanning and X-ray has had an important impact. Materials and Methods: We assessed the prevalence of lung lesions in vaccinated versus unvaccinated SARS-CoV-2 patients using an artificial intelligence (AI) platform provided by Medicai. The software analyzes the CT scans, performing the lung and lesion segmentation using a variant of the U-net convolutional network. Results: We conducted a cohort study at a tertiary lung hospital in which we included 186 patients: 107 (57.52%) male and 59 (42.47%) females, of which 157 (84.40%) were not vaccinated for SARS-CoV-2. Over five times more unvaccinated patients than vaccinated ones are admitted to the hospital and require imaging investigations. More than twice as many unvaccinated patients have more than 75% of the lungs affected. Patients in the age group 30-39 have had the most lung lesions at almost 69% of both lungs affected. Compared to vaccinated patients with comorbidities, unvaccinated patients with comorbidities had developed increased lung lesions by 5%. Conclusion: The study revealed a higher percentage of lung lesions among unvaccinated SARS-CoV-2-positive patients admitted to The National Institute of Pulmonology "Marius Nasta" in Bucharest, Romania, underlining the importance of vaccination and also the usefulness of artificial intelligence in CT interpretation.
Keywords
lung lesion, SARS-CoV-2, vaccination, image interpretation, artificial, intelligence, PULMONARY NODULES, MEDICINE, CHATGPT, AI

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MLA
Stoichita, Alexandru, et al. “Imagistic Findings Using Artificial Intelligence in Vaccinated versus Unvaccinated SARS-CoV-2-Positive Patients Receiving in-Care Treatment at a Tertiary Lung Hospital.” JOURNAL OF CLINICAL MEDICINE, vol. 12, no. 22, 2023, doi:10.3390/jcm12227115.
APA
Stoichita, A., Ghita, M., Mahler, B., Vlasceanu, S., Ghinet, A., Mosteanu, M., … Iliesiu, A. (2023). Imagistic findings using artificial intelligence in vaccinated versus unvaccinated SARS-CoV-2-positive patients receiving in-care treatment at a tertiary lung hospital. JOURNAL OF CLINICAL MEDICINE, 12(22). https://doi.org/10.3390/jcm12227115
Chicago author-date
Stoichita, Alexandru, Maria Ghita, Beatrice Mahler, Silviu Vlasceanu, Andreea Ghinet, Madalina Mosteanu, Andreea Cioacata, et al. 2023. “Imagistic Findings Using Artificial Intelligence in Vaccinated versus Unvaccinated SARS-CoV-2-Positive Patients Receiving in-Care Treatment at a Tertiary Lung Hospital.” JOURNAL OF CLINICAL MEDICINE 12 (22). https://doi.org/10.3390/jcm12227115.
Chicago author-date (all authors)
Stoichita, Alexandru, Maria Ghita, Beatrice Mahler, Silviu Vlasceanu, Andreea Ghinet, Madalina Mosteanu, Andreea Cioacata, Andreea Udrea, Alina Marcu, George Daniel Mitra, Clara-Mihaela Ionescu, and Adriana Iliesiu. 2023. “Imagistic Findings Using Artificial Intelligence in Vaccinated versus Unvaccinated SARS-CoV-2-Positive Patients Receiving in-Care Treatment at a Tertiary Lung Hospital.” JOURNAL OF CLINICAL MEDICINE 12 (22). doi:10.3390/jcm12227115.
Vancouver
1.
Stoichita A, Ghita M, Mahler B, Vlasceanu S, Ghinet A, Mosteanu M, et al. Imagistic findings using artificial intelligence in vaccinated versus unvaccinated SARS-CoV-2-positive patients receiving in-care treatment at a tertiary lung hospital. JOURNAL OF CLINICAL MEDICINE. 2023;12(22).
IEEE
[1]
A. Stoichita et al., “Imagistic findings using artificial intelligence in vaccinated versus unvaccinated SARS-CoV-2-positive patients receiving in-care treatment at a tertiary lung hospital,” JOURNAL OF CLINICAL MEDICINE, vol. 12, no. 22, 2023.
@article{01HPESE0M5Y2T9HFHTEJ7FY9H4,
  abstract     = {{Background: In December 2019 the World Health Organization announced that the widespread severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection had become a global pandemic. The most affected organ by the novel virus is the lung, and imaging exploration of the thorax using computer tomography (CT) scanning and X-ray has had an important impact. Materials and Methods: We assessed the prevalence of lung lesions in vaccinated versus unvaccinated SARS-CoV-2 patients using an artificial intelligence (AI) platform provided by Medicai. The software analyzes the CT scans, performing the lung and lesion segmentation using a variant of the U-net convolutional network. Results: We conducted a cohort study at a tertiary lung hospital in which we included 186 patients: 107 (57.52%) male and 59 (42.47%) females, of which 157 (84.40%) were not vaccinated for SARS-CoV-2. Over five times more unvaccinated patients than vaccinated ones are admitted to the hospital and require imaging investigations. More than twice as many unvaccinated patients have more than 75% of the lungs affected. Patients in the age group 30-39 have had the most lung lesions at almost 69% of both lungs affected. Compared to vaccinated patients with comorbidities, unvaccinated patients with comorbidities had developed increased lung lesions by 5%. Conclusion: The study revealed a higher percentage of lung lesions among unvaccinated SARS-CoV-2-positive patients admitted to The National Institute of Pulmonology "Marius Nasta" in Bucharest, Romania, underlining the importance of vaccination and also the usefulness of artificial intelligence in CT interpretation.}},
  articleno    = {{7115}},
  author       = {{Stoichita, Alexandru and Ghita, Maria and Mahler, Beatrice and Vlasceanu, Silviu and Ghinet, Andreea and Mosteanu, Madalina and Cioacata, Andreea and Udrea, Andreea and Marcu, Alina and Mitra, George Daniel and Ionescu, Clara-Mihaela and Iliesiu, Adriana}},
  issn         = {{2077-0383}},
  journal      = {{JOURNAL OF CLINICAL MEDICINE}},
  keywords     = {{lung lesion,SARS-CoV-2,vaccination,image interpretation,artificial,intelligence,PULMONARY NODULES,MEDICINE,CHATGPT,AI}},
  language     = {{eng}},
  number       = {{22}},
  pages        = {{11}},
  title        = {{Imagistic findings using artificial intelligence in vaccinated versus unvaccinated SARS-CoV-2-positive patients receiving in-care treatment at a tertiary lung hospital}},
  url          = {{http://doi.org/10.3390/jcm12227115}},
  volume       = {{12}},
  year         = {{2023}},
}

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