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Association of anatomical variants of the sacroiliac joint with bone marrow edema in patients with axial spondyloarthritis

(2024) SKELETAL RADIOLOGY. 53(3). p.507-514
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Abstract
ObjectiveTo determine the prevalence of sacroiliac joint variants in patients with axial spondyloarthritis (axSpA) using MRI-based synthetic CT images and to evaluate their relationships with the presence of bone marrow edema, as this may potentially complicate diagnosing active sacroiliitis on MRI in patients with suspected axSpA.Methods172 patients were retrospectively included. All patients underwent MRI because of clinical suspicion of sacroiliitis. The diagnosis of axSpA was made by a tertiary hospital rheumatologist. Two readers independently determined the presence of bone marrow edema and the presence of one or more of the nine known sacroiliac joint (SIJ) variants.ResultsSIJ variants were common in axSpA patients (82.9%) and the non-SpA group (85.4%); there were no significant differences in prevalence. Bone marrow edema was frequently found in axSpA (86.8%) and non-SpA patients (34%). AxSpA patients with SIJ variants (except for accessory joint) demonstrated 4 to 10 times higher odds for bone marrow edema, however not statistically significant. The more variants were present in this group, the higher the chance of bone marrow edema. However, some multicollinearity cannot be excluded, since bone marrow edema is very frequent in the axSpA group by definition.ConclusionSIJ variants are common in axSpA and non-SpA patients. SIJ variants were associated with higher prevalence of bone marrow edema in axSpA patients, potentially due to altered biomechanics, except for accessory joint which may act as a stabilizer.
Keywords
PREVALENCE, MRI, Sacroiliac Joint, Spondyloarthritis, Spondyloarthropathies, Anatomic Variation, Magnetic Resonance Imaging

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MLA
Vereecke, Elke, et al. “Association of Anatomical Variants of the Sacroiliac Joint with Bone Marrow Edema in Patients with Axial Spondyloarthritis.” SKELETAL RADIOLOGY, vol. 53, no. 3, 2024, pp. 507–14, doi:10.1007/s00256-023-04435-z.
APA
Vereecke, E., Jans, L., Herregods, N., Chen, M., Jaremko, J. L., Laloo, F., … Morbée, L. (2024). Association of anatomical variants of the sacroiliac joint with bone marrow edema in patients with axial spondyloarthritis. SKELETAL RADIOLOGY, 53(3), 507–514. https://doi.org/10.1007/s00256-023-04435-z
Chicago author-date
Vereecke, Elke, Lennart Jans, Nele Herregods, Min Chen, Jacob L. Jaremko, Frederiek Laloo, Philippe Carron, et al. 2024. “Association of Anatomical Variants of the Sacroiliac Joint with Bone Marrow Edema in Patients with Axial Spondyloarthritis.” SKELETAL RADIOLOGY 53 (3): 507–14. https://doi.org/10.1007/s00256-023-04435-z.
Chicago author-date (all authors)
Vereecke, Elke, Lennart Jans, Nele Herregods, Min Chen, Jacob L. Jaremko, Frederiek Laloo, Philippe Carron, Gaëlle Varkas, Manouk de Hooge, Filip Van den Bosch, Dirk Elewaut, and Lieve Morbée. 2024. “Association of Anatomical Variants of the Sacroiliac Joint with Bone Marrow Edema in Patients with Axial Spondyloarthritis.” SKELETAL RADIOLOGY 53 (3): 507–514. doi:10.1007/s00256-023-04435-z.
Vancouver
1.
Vereecke E, Jans L, Herregods N, Chen M, Jaremko JL, Laloo F, et al. Association of anatomical variants of the sacroiliac joint with bone marrow edema in patients with axial spondyloarthritis. SKELETAL RADIOLOGY. 2024;53(3):507–14.
IEEE
[1]
E. Vereecke et al., “Association of anatomical variants of the sacroiliac joint with bone marrow edema in patients with axial spondyloarthritis,” SKELETAL RADIOLOGY, vol. 53, no. 3, pp. 507–514, 2024.
@article{01HNJ72Q093V9H0YCAG9X5HBZV,
  abstract     = {{ObjectiveTo determine the prevalence of sacroiliac joint variants in patients with axial spondyloarthritis (axSpA) using MRI-based synthetic CT images and to evaluate their relationships with the presence of bone marrow edema, as this may potentially complicate diagnosing active sacroiliitis on MRI in patients with suspected axSpA.Methods172 patients were retrospectively included. All patients underwent MRI because of clinical suspicion of sacroiliitis. The diagnosis of axSpA was made by a tertiary hospital rheumatologist. Two readers independently determined the presence of bone marrow edema and the presence of one or more of the nine known sacroiliac joint (SIJ) variants.ResultsSIJ variants were common in axSpA patients (82.9%) and the non-SpA group (85.4%); there were no significant differences in prevalence. Bone marrow edema was frequently found in axSpA (86.8%) and non-SpA patients (34%). AxSpA patients with SIJ variants (except for accessory joint) demonstrated 4 to 10 times higher odds for bone marrow edema, however not statistically significant. The more variants were present in this group, the higher the chance of bone marrow edema. However, some multicollinearity cannot be excluded, since bone marrow edema is very frequent in the axSpA group by definition.ConclusionSIJ variants are common in axSpA and non-SpA patients. SIJ variants were associated with higher prevalence of bone marrow edema in axSpA patients, potentially due to altered biomechanics, except for accessory joint which may act as a stabilizer.}},
  author       = {{Vereecke, Elke and Jans, Lennart and Herregods, Nele and Chen, Min and  Jaremko, Jacob L. and Laloo, Frederiek and Carron, Philippe and Varkas, Gaëlle and de Hooge, Manouk and Van den Bosch, Filip and Elewaut, Dirk and Morbée, Lieve}},
  issn         = {{0364-2348}},
  journal      = {{SKELETAL RADIOLOGY}},
  keywords     = {{PREVALENCE,MRI,Sacroiliac Joint,Spondyloarthritis,Spondyloarthropathies,Anatomic Variation,Magnetic Resonance Imaging}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{507--514}},
  title        = {{Association of anatomical variants of the sacroiliac joint with bone marrow edema in patients with axial spondyloarthritis}},
  url          = {{http://doi.org/10.1007/s00256-023-04435-z}},
  volume       = {{53}},
  year         = {{2024}},
}

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