@article{01HDGSXQVRQ5CWZ9BSBT1BJHWS,
  abstract     = {{Studying microplastics and nanoplastics (MNP) in environmental matrices is extremely challenging, and recent developments in labelling techniques may hold much promise to further our knowledge in this field. Here, we reviewed MNP labelling techniques and applications to provide the first systematic and in-depth insight into MNP labelling. We classified all labelling techniques for MNP into four main types (fluorescent, metal, stable isotope and radioisotope) and discussed per type the synthesis methods, detection methods, influencing factors, and the current and future applications and challenges. Direct labelling of environmental MNP with fluorescent dyes and metals enables simple visualisation and selective detection of MNP to improve detection efficiency. However, it is still an open question how to avoid co-labelling of non-plastic (i.e. non-target, matrix) materials. Labelling of MNP that are intentionally added in the environment may allow semi-automatic detection of MNP particles with high accuracy and sensitivity during studies on e.g. transport and degradation. The detection limit of labelled MNP largely depends on particle size and the type of matrix. Fluorescent labelling allows efficient detection of microplastics, whereas metal labelling is preferred for nanoplastics research due to a potentially higher sensitivity. A major challenge for fluorescent and metal labelling is to develop techniques that do not alter the inherent MNP properties or only do so minimally, in particular the surface properties. Stable and radioactive isotope labelling (13C and 14C, but also 15N, 2H) of the polymer itself allows to preserve inherent MNP properties, but have been largely ignored. Overall, labelling of MNP holds great promise for advancing our fundamental understanding of the behaviour of plastics, notably the smallest fractions, in the environment.}},
  articleno    = {{132785}},
  author       = {{Liu, Yin and Li, Jie and Parakhonskiy, Bogdan and Hoogenboom, Richard and Skirtach, Andre and De Neve, Stefaan}},
  issn         = {{0304-3894}},
  journal      = {{JOURNAL OF HAZARDOUS MATERIALS}},
  keywords     = {{Microplastic detection,Nanoplastics,Labelling,Leaching,Label induced alterations}},
  language     = {{eng}},
  pages        = {{18}},
  title        = {{Labelling of micro- and nanoplastics for environmental studies : state-of-the-art and future challenges}},
  url          = {{http://doi.org/10.1016/j.jhazmat.2023.132785}},
  volume       = {{462}},
  year         = {{2024}},
}

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