Priming of the murine mammary gland with Staphylococcus chromogenes IM reduces bacterial growth of Streptococcus uberis : a proof-of-concept study
- Author
- Niels Vander Elst (UGent) , Julie Bellemans (UGent) , Jonas Steenbrugge (UGent) , Chloë Geeroms, Koen Breyne (UGent) , Sofie Piepers (UGent) , Bruno Toledo-Silva (UGent) , Fernando Nogueira De Souza (UGent) , Freddy Haesebrouck (UGent) , Sarne De Vliegher (UGent) and Evelyne Meyer (UGent)
- Organization
- Abstract
- Streptococcus uberis is a major causative agent of bovine mastitis, an inflammation of the mammary gland with substantial economic consequences. To reduce antibiotic use in animal agriculture, alternative strategies to treat or prevent mastitis are being investigated. Bovine-associated non-aureus staphylococci are proposed in that respect due to their capacity to inhibit the in vitro growth of S. uberis. We demonstrate that priming the murine mammary gland with Staphylococcus chromogenes IM reduces S. uberis growth in comparison with non-primed glands. The innate immune system is activated by increasing IL-8 and LCN2, which may explain this decreased growth.
- Keywords
- General Veterinary, dairy cow, bovine mastitis, Staphylococcus chromogenes, Streptococcus uberis, priming, Non-aureus staphylococci
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-01HBG13H4ZTFZ88GG2T4XAJVTJ
- MLA
- Vander Elst, Niels, et al. “Priming of the Murine Mammary Gland with Staphylococcus Chromogenes IM Reduces Bacterial Growth of Streptococcus Uberis : A Proof-of-Concept Study.” VETERINARY RESEARCH, vol. 54, no. 1, Springer Science and Business Media LLC, 2023, doi:10.1186/s13567-023-01156-y.
- APA
- Vander Elst, N., Bellemans, J., Steenbrugge, J., Geeroms, C., Breyne, K., Piepers, S., … Meyer, E. (2023). Priming of the murine mammary gland with Staphylococcus chromogenes IM reduces bacterial growth of Streptococcus uberis : a proof-of-concept study. VETERINARY RESEARCH, 54(1). https://doi.org/10.1186/s13567-023-01156-y
- Chicago author-date
- Vander Elst, Niels, Julie Bellemans, Jonas Steenbrugge, Chloë Geeroms, Koen Breyne, Sofie Piepers, Bruno Toledo-Silva, et al. 2023. “Priming of the Murine Mammary Gland with Staphylococcus Chromogenes IM Reduces Bacterial Growth of Streptococcus Uberis : A Proof-of-Concept Study.” VETERINARY RESEARCH 54 (1). https://doi.org/10.1186/s13567-023-01156-y.
- Chicago author-date (all authors)
- Vander Elst, Niels, Julie Bellemans, Jonas Steenbrugge, Chloë Geeroms, Koen Breyne, Sofie Piepers, Bruno Toledo-Silva, Fernando Nogueira De Souza, Freddy Haesebrouck, Sarne De Vliegher, and Evelyne Meyer. 2023. “Priming of the Murine Mammary Gland with Staphylococcus Chromogenes IM Reduces Bacterial Growth of Streptococcus Uberis : A Proof-of-Concept Study.” VETERINARY RESEARCH 54 (1). doi:10.1186/s13567-023-01156-y.
- Vancouver
- 1.Vander Elst N, Bellemans J, Steenbrugge J, Geeroms C, Breyne K, Piepers S, et al. Priming of the murine mammary gland with Staphylococcus chromogenes IM reduces bacterial growth of Streptococcus uberis : a proof-of-concept study. VETERINARY RESEARCH. 2023;54(1).
- IEEE
- [1]N. Vander Elst et al., “Priming of the murine mammary gland with Staphylococcus chromogenes IM reduces bacterial growth of Streptococcus uberis : a proof-of-concept study,” VETERINARY RESEARCH, vol. 54, no. 1, 2023.
@article{01HBG13H4ZTFZ88GG2T4XAJVTJ, abstract = {{Streptococcus uberis is a major causative agent of bovine mastitis, an inflammation of the mammary gland with substantial economic consequences. To reduce antibiotic use in animal agriculture, alternative strategies to treat or prevent mastitis are being investigated. Bovine-associated non-aureus staphylococci are proposed in that respect due to their capacity to inhibit the in vitro growth of S. uberis. We demonstrate that priming the murine mammary gland with Staphylococcus chromogenes IM reduces S. uberis growth in comparison with non-primed glands. The innate immune system is activated by increasing IL-8 and LCN2, which may explain this decreased growth.}}, articleno = {{28}}, author = {{Vander Elst, Niels and Bellemans, Julie and Steenbrugge, Jonas and Geeroms, Chloë and Breyne, Koen and Piepers, Sofie and Toledo-Silva, Bruno and Nogueira De Souza, Fernando and Haesebrouck, Freddy and De Vliegher, Sarne and Meyer, Evelyne}}, issn = {{0928-4249}}, journal = {{VETERINARY RESEARCH}}, keywords = {{General Veterinary,dairy cow,bovine mastitis,Staphylococcus chromogenes,Streptococcus uberis,priming,Non-aureus staphylococci}}, language = {{eng}}, number = {{1}}, pages = {{8}}, publisher = {{Springer Science and Business Media LLC}}, title = {{Priming of the murine mammary gland with Staphylococcus chromogenes IM reduces bacterial growth of Streptococcus uberis : a proof-of-concept study}}, url = {{http://doi.org/10.1186/s13567-023-01156-y}}, volume = {{54}}, year = {{2023}}, }
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