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Robustness analysis of a fractional order control system for the hemodynamic variables in anesthetized patients

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Abstract
Computer-based control of anesthesia is a puzzle requiring multiple other states to be suitably monitored and controlled. Among these, hemodynamic stabilization is a must. Very few studies have been reported regarding the automatic control of the combined anesthesia-hemodynamic systems. Hemodynamic states are strongly affected by hypnotic drugs. At the same time, drugs used for hemodynamic control influence the depth of hypnosis. In this paper, a solution to maintain anesthetic and hemodynamic variables within safe operating ranges is presented and consists in a multivariable fractional order controller. The robustness of the proposed solution is analysed by considering a benchmark patient model and data from 24 patients.
Keywords
PREDICTIVE CONTROL, CONTROL STRATEGY, ANESTHESIA, PROPOFOL, MODEL, HYPNOSIS

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MLA
Hegedus, Erwin, et al. “Robustness Analysis of a Fractional Order Control System for the Hemodynamic Variables in Anesthetized Patients.” 2023 EUROPEAN CONTROL CONFERENCE, ECC, IEEE, 2023, doi:10.23919/ECC57647.2023.10178146.
APA
Hegedus, E., Ghita, M., Birs, I. R., Copot, D., & Muresan, C. I. (2023). Robustness analysis of a fractional order control system for the hemodynamic variables in anesthetized patients. 2023 EUROPEAN CONTROL CONFERENCE, ECC. Presented at the European Control Conference (ECC), Bucharest, ROMANIA. https://doi.org/10.23919/ECC57647.2023.10178146
Chicago author-date
Hegedus, Erwin, Mihaela Ghita, Isabela Roxana Birs, Dana Copot, and Cristina I. Muresan. 2023. “Robustness Analysis of a Fractional Order Control System for the Hemodynamic Variables in Anesthetized Patients.” In 2023 EUROPEAN CONTROL CONFERENCE, ECC. IEEE. https://doi.org/10.23919/ECC57647.2023.10178146.
Chicago author-date (all authors)
Hegedus, Erwin, Mihaela Ghita, Isabela Roxana Birs, Dana Copot, and Cristina I. Muresan. 2023. “Robustness Analysis of a Fractional Order Control System for the Hemodynamic Variables in Anesthetized Patients.” In 2023 EUROPEAN CONTROL CONFERENCE, ECC. IEEE. doi:10.23919/ECC57647.2023.10178146.
Vancouver
1.
Hegedus E, Ghita M, Birs IR, Copot D, Muresan CI. Robustness analysis of a fractional order control system for the hemodynamic variables in anesthetized patients. In: 2023 EUROPEAN CONTROL CONFERENCE, ECC. IEEE; 2023.
IEEE
[1]
E. Hegedus, M. Ghita, I. R. Birs, D. Copot, and C. I. Muresan, “Robustness analysis of a fractional order control system for the hemodynamic variables in anesthetized patients,” in 2023 EUROPEAN CONTROL CONFERENCE, ECC, Bucharest, ROMANIA, 2023.
@inproceedings{01HA705965ZEC8W6MDH3808GMA,
  abstract     = {{Computer-based control of anesthesia is a puzzle requiring multiple other states to be suitably monitored and controlled. Among these, hemodynamic stabilization is a must. Very few studies have been reported regarding the automatic control of the combined anesthesia-hemodynamic systems. Hemodynamic states are strongly affected by hypnotic drugs. At the same time, drugs used for hemodynamic control influence the depth of hypnosis. In this paper, a solution to maintain anesthetic and hemodynamic variables within safe operating ranges is presented and consists in a multivariable fractional order controller. The robustness of the proposed solution is analysed by considering a benchmark patient model and data from 24 patients.}},
  author       = {{Hegedus, Erwin and Ghita, Mihaela and Birs, Isabela Roxana and Copot, Dana and  Muresan, Cristina I.}},
  booktitle    = {{2023 EUROPEAN CONTROL CONFERENCE, ECC}},
  isbn         = {{9783907144084}},
  keywords     = {{PREDICTIVE CONTROL,CONTROL STRATEGY,ANESTHESIA,PROPOFOL,MODEL,HYPNOSIS}},
  language     = {{eng}},
  location     = {{Bucharest, ROMANIA}},
  pages        = {{6}},
  publisher    = {{IEEE}},
  title        = {{Robustness analysis of a fractional order control system for the hemodynamic variables in anesthetized patients}},
  url          = {{http://doi.org/10.23919/ECC57647.2023.10178146}},
  year         = {{2023}},
}

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