- Author
- Marine Roche-Catholy
- Promoter
- Pascale Smets (UGent) and Dominique Paepe (UGent)
- Organization
- Abstract
- Congestive heart failure (CHF) is a complex clinical syndrome affecting both people and small animals, is characterized by severe clinical signs (e.g. dyspnea, cough, exercise intolerance) and is associated with high morbidity and mortality. Currently, the loop diuretic furosemide is the cornerstone of CHF treatment because it reduces fluid congestion, and thus alleviates the clinical signs. However, response to this diuretic can vary greatly among humans, and progressive increase in dose to maintain the same level of diuresis can be necessary in some cases, a concept known as diuretic resistance in people. Consequently, the need to switch from furosemide to alternative diuretics has been suggested. Another loop diuretic torasemide was found to provide lower mortality and hospital readmission rates compared to furosemide. Few studies have outlined benefits of the use of torasemide in dogs, but little is known about its pharmacological properties and clinical implications in cats. Additionally, diuretic resistance is also suspected to occur dogs and cats, but reports are scarce and no diagnostic technique has been fully validated to identify such a phenomenon.
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-01H4QEY4ZCDQFM1EYQW1XPEA83
- MLA
- Roche-Catholy, Marine. Loop Diuretic Therapy for Congestive Heart Failure in Dogs and Cats : What Are We Missing? Ghent University. Faculty of Veterinary Medicine, 2023.
- APA
- Roche-Catholy, M. (2023). Loop diuretic therapy for congestive heart failure in dogs and cats : what are we missing? Ghent University. Faculty of Veterinary Medicine, Merelbeke, Belgium.
- Chicago author-date
- Roche-Catholy, Marine. 2023. “Loop Diuretic Therapy for Congestive Heart Failure in Dogs and Cats : What Are We Missing?” Merelbeke, Belgium: Ghent University. Faculty of Veterinary Medicine.
- Chicago author-date (all authors)
- Roche-Catholy, Marine. 2023. “Loop Diuretic Therapy for Congestive Heart Failure in Dogs and Cats : What Are We Missing?” Merelbeke, Belgium: Ghent University. Faculty of Veterinary Medicine.
- Vancouver
- 1.Roche-Catholy M. Loop diuretic therapy for congestive heart failure in dogs and cats : what are we missing? [Merelbeke, Belgium]: Ghent University. Faculty of Veterinary Medicine; 2023.
- IEEE
- [1]M. Roche-Catholy, “Loop diuretic therapy for congestive heart failure in dogs and cats : what are we missing?,” Ghent University. Faculty of Veterinary Medicine, Merelbeke, Belgium, 2023.
@phdthesis{01H4QEY4ZCDQFM1EYQW1XPEA83, abstract = {{Congestive heart failure (CHF) is a complex clinical syndrome affecting both people and small animals, is characterized by severe clinical signs (e.g. dyspnea, cough, exercise intolerance) and is associated with high morbidity and mortality. Currently, the loop diuretic furosemide is the cornerstone of CHF treatment because it reduces fluid congestion, and thus alleviates the clinical signs. However, response to this diuretic can vary greatly among humans, and progressive increase in dose to maintain the same level of diuresis can be necessary in some cases, a concept known as diuretic resistance in people. Consequently, the need to switch from furosemide to alternative diuretics has been suggested. Another loop diuretic torasemide was found to provide lower mortality and hospital readmission rates compared to furosemide. Few studies have outlined benefits of the use of torasemide in dogs, but little is known about its pharmacological properties and clinical implications in cats. Additionally, diuretic resistance is also suspected to occur dogs and cats, but reports are scarce and no diagnostic technique has been fully validated to identify such a phenomenon.}}, author = {{Roche-Catholy, Marine}}, language = {{eng}}, pages = {{VIII, 203}}, publisher = {{Ghent University. Faculty of Veterinary Medicine}}, school = {{Ghent University}}, title = {{Loop diuretic therapy for congestive heart failure in dogs and cats : what are we missing?}}, year = {{2023}}, }