
Vulnerable newborn types : analysis of subnational, population‐based birth cohorts for 541 285 live births in 23 countries, 2000-2021
- Author
- D. J. Erchick, E. A. Hazel, J. Katz, A. C. C. Lee, M. Diaz, L. S. F. Wu, S. Yoshida, R. Bahl, C. Grandi, A. B. Labrique, M. Rashid, S. Ahmed, A. D. Roy, R. Haque, S. Shaikh, A. H. Baqui, S. K. Saha, R. Khanam, S. Rahman, R. Shapiro, R. Zash, M. F. Silveira, R. Buffarini, Patrick Kolsteren (UGent) , Carl Lachat (UGent) , Lieven Huybregts (UGent) , D. Roberfroid, L. Zeng, Z. Zhu, J. He, X. Qiu, S. H. Gebreyesus, Kokeb Tesfamariam Hadush (UGent) , D. Bekele, G. Chan, E. Baye, F. Workneh, K. P. Asante, E. B. Kaali, S. Adu‐Afarwuah, K. G. Dewey, S. Gyaase, B. J. Wylie, B. R. Kirkwood, A. Manu, R. D. Thulasiraj, J. Tielsch, R. Chowdhury, S. Taneja, G. R. Babu, P. Shriyan, P. Ashorn, K. Maleta, U. Ashorn, C. Mangani, S. Acevedo‐Gallegos, M. J. Rodriguez‐Sibaja, S. K. Khatry, S. C. LeClerq, L. C. Mullany, F. Jehan, M. Ilyas, S. J. Rogerson, H. W. Unger, R. Ghosh, S. Musange, V. Ramokolo, W. Zembe‐Mkabile, M. Lazzerini, M. Rishard, D. Wang, W. W. Fawzi, D. T. R. Minja, C. Schmiegelow, H. Masanja, E. Smith, J. P. A. Lusingu, O. A. Msemo, F. M. Kabole, S. N. Slim, P. Keentupthai, A. Mongkolchati, R. Kajubi, A. Kakuru, P. Waiswa, D. Walker, D. H. Hamer, K. E. A. Semrau, E. B. Chaponda, R. M. Chico, B. Banda, K. Musokotwane, A. Manasyan, J. M. Pry, B. Chasekwa, J. Humphrey, R. E. Black, Hasmot Ali, Parul Christian, Rolf D. W. Klemm, Alan B. Massie, Maithili Mitra, Sucheta Mehra, Kerry J. Schulze, Abu Ahmed Shamim, Alfred Sommer, MD. Barkat Ullah, Keith P. West, Nazma Begum, Nabidul Haque Chowdhury, Md. Shafiqul Islam, Dipak Kumar Mitra, Abdul Quaiyum, Modiegi Diseko, Joseph Makhema, Yue Cheng, Yixin Guo, Shanshan Yuan, Meselech Roro, Bilal Shikur, Frederick Goddard, Sebastien Haneuse, Bezawit Hunegnaw, Yemane Berhane, Alemayehu Worku, Seyram Kaali, Charles D. Arnold, Darby Jack, Seeba Amenga‐Etego, Lisa Hurt, Caitlin Shannon, Seyi Soremekun, Nita Bhandari, Jose Martines, Sarmila Mazumder, Yamuna Ana, R Deepa, Lotta Hallamaa, Juha Pyykkö, Mario I. Lumbreras‐Marquez, Claudia E. Mendoza‐Carrera, Atiya Hussain, Muhammad Karim, Farzana Kausar, Usma Mehmood, Naila Nadeem, Muhammad Imran Nisar, Muhammad Sajid, Ivo Mueller, Maria Ome‐Kaius, Elizabeth Butrick, Felix Sayinzoga, Ilaria Mariani, Willy Urassa, Thor Theander, Phillippe Deloron, Birgitte Bruun Nielsen, Alfa Muhihi, Ramadhani Abdallah Noor, Ib Bygbjerg, Sofie Lykke Moeller, Fahad Aftab, Said M. Ali, Pratibha Dhingra, Usha Dhingra, Arup Dutta, Sunil Sazawal, Atifa Suleiman, Mohammed Mohammed, Saikat Deb, Moses R. Kamya, Miriam Nakalembe, Jude Mulowooz, Nicole Santos, Godfrey Biemba, Julie M. Herlihy, Reuben K. Mbewe, Fern Mweena, Kojo Yeboah‐Antwi, Jane Bruce, Daniel Chandramohan, Andrew Prendergast, Joy E. Lawn, Hannah Blencowe, Eric Ohuma, Yemi Okwaraji, Judith Yargawa, Ellen Bradley, Joanne Katz and [missing] the Subnational Vulnerable Newborn Prevalence Collaborative Group and Vulnerable Newborn Measurement Core Group
- Organization
- Abstract
- Setting: Subnational, population-based birth cohort studies (n = 45) in 23 low-and middle-income countries (LMICs) spanning 2000–2021. Population: Liveborn infants. Methods: Subnational, population-based studies with high-quality birth outcome data from LMICs were invited to join the Vulnerable Newborn Measurement Collaboration. We defined distinct newborn types using gestational age (preterm [PT], term [T]), birthweight for gestational age using INTERGROWTH-21st standards (small for gestational age [SGA], appropriate for gestational age [AGA] or large for gestational age [LGA]), and birthweight (low birthweight, LBW [<2500 g], non- LBW) as ten types (using all three outcomes), six types (by excluding the birthweight categorisation), and four types (by collapsing the AGA and LGA categories). We defined small types as those with at least one classification of LBW, PT or SGA. We presented study characteristics, participant characteristics, data missingness, and prevalence of newborn types by region and study. Results: Among 541 285 live births, 476 939 (88.1%) had non-missing and plausible values for gestational age, birthweight and sex required to construct the newborn types. The median prevalences of ten types across studies were T+AGA+nonLBW (58.0%), T+LGA+nonLBW (3.3%), T+AGA+LBW (0.5%), T+SGA+nonLBW (14.2%), T+SGA+LBW (7.1%), PT+LGA+nonLBW (1.6%), PT+LGA+LBW (0.2%), PT+AGA+nonLBW (3.7%), PT+AGA+LBW (3.6%) and PT+SGA+LBW (1.0%). The median prevalence of small types (six types, 37.6%) varied across studies and within regions and was higher in Southern Asia (52.4%) than in Sub-Saharan Africa (34.9%). Conclusions: Further investigation is needed to describe the mortality risks associated with newborn types and understand the implications of this framework for local targeting of interventions to prevent adverse pregnancy outcomes in LMICs.
- Keywords
- low birthweight, newborn, preterm birth, small for gestational age, FOR-GESTATIONAL-AGE, MIDDLE-INCOME COUNTRIES, MORTALITY, RISK, PRETERM, INFANTS, WEIGHT, TERM
Downloads
-
BJOG - 2023 - Erchick - Vulnerable newborn types analysis of subnational population‐based birth cohorts for 541 285 live.pdf
- full text (Published version)
- |
- open access
- |
- |
- 4.53 MB
Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-01GZZM26M8GBMG52W5DGH0SN7W
- MLA
- Erchick, D. J., et al. “Vulnerable Newborn Types : Analysis of Subnational, Population‐based Birth Cohorts for 541 285 Live Births in 23 Countries, 2000-2021.” BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2025, pp. 1–17, doi:10.1111/1471-0528.17510.
- APA
- Erchick, D. J., Hazel, E. A., Katz, J., Lee, A. C. C., Diaz, M., Wu, L. S. F., … the Subnational Vulnerable Newborn Prevalence Collaborative Group and Vulnerable Newborn Measurement Core Group, [missing]. (2025). Vulnerable newborn types : analysis of subnational, population‐based birth cohorts for 541 285 live births in 23 countries, 2000-2021. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1–17. https://doi.org/10.1111/1471-0528.17510
- Chicago author-date
- Erchick, D. J., E. A. Hazel, J. Katz, A. C. C. Lee, M. Diaz, L. S. F. Wu, S. Yoshida, et al. 2025. “Vulnerable Newborn Types : Analysis of Subnational, Population‐based Birth Cohorts for 541 285 Live Births in 23 Countries, 2000-2021.” BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1–17. https://doi.org/10.1111/1471-0528.17510.
- Chicago author-date (all authors)
- Erchick, D. J., E. A. Hazel, J. Katz, A. C. C. Lee, M. Diaz, L. S. F. Wu, S. Yoshida, R. Bahl, C. Grandi, A. B. Labrique, M. Rashid, S. Ahmed, A. D. Roy, R. Haque, S. Shaikh, A. H. Baqui, S. K. Saha, R. Khanam, S. Rahman, R. Shapiro, R. Zash, M. F. Silveira, R. Buffarini, Patrick Kolsteren, Carl Lachat, Lieven Huybregts, D. Roberfroid, L. Zeng, Z. Zhu, J. He, X. Qiu, S. H. Gebreyesus, Kokeb Tesfamariam Hadush, D. Bekele, G. Chan, E. Baye, F. Workneh, K. P. Asante, E. B. Kaali, S. Adu‐Afarwuah, K. G. Dewey, S. Gyaase, B. J. Wylie, B. R. Kirkwood, A. Manu, R. D. Thulasiraj, J. Tielsch, R. Chowdhury, S. Taneja, G. R. Babu, P. Shriyan, P. Ashorn, K. Maleta, U. Ashorn, C. Mangani, S. Acevedo‐Gallegos, M. J. Rodriguez‐Sibaja, S. K. Khatry, S. C. LeClerq, L. C. Mullany, F. Jehan, M. Ilyas, S. J. Rogerson, H. W. Unger, R. Ghosh, S. Musange, V. Ramokolo, W. Zembe‐Mkabile, M. Lazzerini, M. Rishard, D. Wang, W. W. Fawzi, D. T. R. Minja, C. Schmiegelow, H. Masanja, E. Smith, J. P. A. Lusingu, O. A. Msemo, F. M. Kabole, S. N. Slim, P. Keentupthai, A. Mongkolchati, R. Kajubi, A. Kakuru, P. Waiswa, D. Walker, D. H. Hamer, K. E. A. Semrau, E. B. Chaponda, R. M. Chico, B. Banda, K. Musokotwane, A. Manasyan, J. M. Pry, B. Chasekwa, J. Humphrey, R. E. Black, Hasmot Ali, Parul Christian, Rolf D. W. Klemm, Alan B. Massie, Maithili Mitra, Sucheta Mehra, Kerry J. Schulze, Abu Ahmed Shamim, Alfred Sommer, MD. Barkat Ullah, Keith P. West, Nazma Begum, Nabidul Haque Chowdhury, Md. Shafiqul Islam, Dipak Kumar Mitra, Abdul Quaiyum, Modiegi Diseko, Joseph Makhema, Yue Cheng, Yixin Guo, Shanshan Yuan, Meselech Roro, Bilal Shikur, Frederick Goddard, Sebastien Haneuse, Bezawit Hunegnaw, Yemane Berhane, Alemayehu Worku, Seyram Kaali, Charles D. Arnold, Darby Jack, Seeba Amenga‐Etego, Lisa Hurt, Caitlin Shannon, Seyi Soremekun, Nita Bhandari, Jose Martines, Sarmila Mazumder, Yamuna Ana, R Deepa, Lotta Hallamaa, Juha Pyykkö, Mario I. Lumbreras‐Marquez, Claudia E. Mendoza‐Carrera, Atiya Hussain, Muhammad Karim, Farzana Kausar, Usma Mehmood, Naila Nadeem, Muhammad Imran Nisar, Muhammad Sajid, Ivo Mueller, Maria Ome‐Kaius, Elizabeth Butrick, Felix Sayinzoga, Ilaria Mariani, Willy Urassa, Thor Theander, Phillippe Deloron, Birgitte Bruun Nielsen, Alfa Muhihi, Ramadhani Abdallah Noor, Ib Bygbjerg, Sofie Lykke Moeller, Fahad Aftab, Said M. Ali, Pratibha Dhingra, Usha Dhingra, Arup Dutta, Sunil Sazawal, Atifa Suleiman, Mohammed Mohammed, Saikat Deb, Moses R. Kamya, Miriam Nakalembe, Jude Mulowooz, Nicole Santos, Godfrey Biemba, Julie M. Herlihy, Reuben K. Mbewe, Fern Mweena, Kojo Yeboah‐Antwi, Jane Bruce, Daniel Chandramohan, Andrew Prendergast, Joy E. Lawn, Hannah Blencowe, Eric Ohuma, Yemi Okwaraji, Judith Yargawa, Ellen Bradley, Joanne Katz, and [missing] the Subnational Vulnerable Newborn Prevalence Collaborative Group and Vulnerable Newborn Measurement Core Group. 2025. “Vulnerable Newborn Types : Analysis of Subnational, Population‐based Birth Cohorts for 541 285 Live Births in 23 Countries, 2000-2021.” BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY: 1–17. doi:10.1111/1471-0528.17510.
- Vancouver
- 1.Erchick DJ, Hazel EA, Katz J, Lee ACC, Diaz M, Wu LSF, et al. Vulnerable newborn types : analysis of subnational, population‐based birth cohorts for 541 285 live births in 23 countries, 2000-2021. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY. 2025;1–17.
- IEEE
- [1]D. J. Erchick et al., “Vulnerable newborn types : analysis of subnational, population‐based birth cohorts for 541 285 live births in 23 countries, 2000-2021,” BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, pp. 1–17, 2025.
@article{01GZZM26M8GBMG52W5DGH0SN7W, abstract = {{Setting: Subnational, population-based birth cohort studies (n = 45) in 23 low-and middle-income countries (LMICs) spanning 2000–2021. Population: Liveborn infants. Methods: Subnational, population-based studies with high-quality birth outcome data from LMICs were invited to join the Vulnerable Newborn Measurement Collaboration. We defined distinct newborn types using gestational age (preterm [PT], term [T]), birthweight for gestational age using INTERGROWTH-21st standards (small for gestational age [SGA], appropriate for gestational age [AGA] or large for gestational age [LGA]), and birthweight (low birthweight, LBW [<2500 g], non- LBW) as ten types (using all three outcomes), six types (by excluding the birthweight categorisation), and four types (by collapsing the AGA and LGA categories). We defined small types as those with at least one classification of LBW, PT or SGA. We presented study characteristics, participant characteristics, data missingness, and prevalence of newborn types by region and study. Results: Among 541 285 live births, 476 939 (88.1%) had non-missing and plausible values for gestational age, birthweight and sex required to construct the newborn types. The median prevalences of ten types across studies were T+AGA+nonLBW (58.0%), T+LGA+nonLBW (3.3%), T+AGA+LBW (0.5%), T+SGA+nonLBW (14.2%), T+SGA+LBW (7.1%), PT+LGA+nonLBW (1.6%), PT+LGA+LBW (0.2%), PT+AGA+nonLBW (3.7%), PT+AGA+LBW (3.6%) and PT+SGA+LBW (1.0%). The median prevalence of small types (six types, 37.6%) varied across studies and within regions and was higher in Southern Asia (52.4%) than in Sub-Saharan Africa (34.9%). Conclusions: Further investigation is needed to describe the mortality risks associated with newborn types and understand the implications of this framework for local targeting of interventions to prevent adverse pregnancy outcomes in LMICs.}}, author = {{Erchick, D. J. and Hazel, E. A. and Katz, J. and Lee, A. C. C. and Diaz, M. and Wu, L. S. F. and Yoshida, S. and Bahl, R. and Grandi, C. and Labrique, A. B. and Rashid, M. and Ahmed, S. and Roy, A. D. and Haque, R. and Shaikh, S. and Baqui, A. H. and Saha, S. K. and Khanam, R. and Rahman, S. and Shapiro, R. and Zash, R. and Silveira, M. F. and Buffarini, R. and Kolsteren, Patrick and Lachat, Carl and Huybregts, Lieven and Roberfroid, D. and Zeng, L. and Zhu, Z. and He, J. and Qiu, X. and Gebreyesus, S. H. and Hadush, Kokeb Tesfamariam and Bekele, D. and Chan, G. and Baye, E. and Workneh, F. and Asante, K. P. and Kaali, E. B. and Adu‐Afarwuah, S. and Dewey, K. G. and Gyaase, S. and Wylie, B. J. and Kirkwood, B. R. and Manu, A. and Thulasiraj, R. D. and Tielsch, J. and Chowdhury, R. and Taneja, S. and Babu, G. R. and Shriyan, P. and Ashorn, P. and Maleta, K. and Ashorn, U. and Mangani, C. and Acevedo‐Gallegos, S. and Rodriguez‐Sibaja, M. J. and Khatry, S. K. and LeClerq, S. C. and Mullany, L. C. and Jehan, F. and Ilyas, M. and Rogerson, S. J. and Unger, H. W. and Ghosh, R. and Musange, S. and Ramokolo, V. and Zembe‐Mkabile, W. and Lazzerini, M. and Rishard, M. and Wang, D. and Fawzi, W. W. and Minja, D. T. R. and Schmiegelow, C. and Masanja, H. and Smith, E. and Lusingu, J. P. A. and Msemo, O. A. and Kabole, F. M. and Slim, S. N. and Keentupthai, P. and Mongkolchati, A. and Kajubi, R. and Kakuru, A. and Waiswa, P. and Walker, D. and Hamer, D. H. and Semrau, K. E. A. and Chaponda, E. B. and Chico, R. M. and Banda, B. and Musokotwane, K. and Manasyan, A. and Pry, J. M. and Chasekwa, B. and Humphrey, J. and Black, R. E. and Ali, Hasmot and Christian, Parul and Klemm, Rolf D. W. and Massie, Alan B. and Mitra, Maithili and Mehra, Sucheta and Schulze, Kerry J. and Shamim, Abu Ahmed and Sommer, Alfred and Barkat Ullah, MD. and West, Keith P. and Begum, Nazma and Chowdhury, Nabidul Haque and Shafiqul Islam, Md. and Mitra, Dipak Kumar and Quaiyum, Abdul and Diseko, Modiegi and Makhema, Joseph and Cheng, Yue and Guo, Yixin and Yuan, Shanshan and Roro, Meselech and Shikur, Bilal and Goddard, Frederick and Haneuse, Sebastien and Hunegnaw, Bezawit and Berhane, Yemane and Worku, Alemayehu and Kaali, Seyram and Arnold, Charles D. and Jack, Darby and Amenga‐Etego, Seeba and Hurt, Lisa and Shannon, Caitlin and Soremekun, Seyi and Bhandari, Nita and Martines, Jose and Mazumder, Sarmila and Ana, Yamuna and Deepa, R and Hallamaa, Lotta and Pyykkö, Juha and Lumbreras‐Marquez, Mario I. and Mendoza‐Carrera, Claudia E. and Hussain, Atiya and Karim, Muhammad and Kausar, Farzana and Mehmood, Usma and Nadeem, Naila and Nisar, Muhammad Imran and Sajid, Muhammad and Mueller, Ivo and Ome‐Kaius, Maria and Butrick, Elizabeth and Sayinzoga, Felix and Mariani, Ilaria and Urassa, Willy and Theander, Thor and Deloron, Phillippe and Nielsen, Birgitte Bruun and Muhihi, Alfa and Noor, Ramadhani Abdallah and Bygbjerg, Ib and Moeller, Sofie Lykke and Aftab, Fahad and Ali, Said M. and Dhingra, Pratibha and Dhingra, Usha and Dutta, Arup and Sazawal, Sunil and Suleiman, Atifa and Mohammed, Mohammed and Deb, Saikat and Kamya, Moses R. and Nakalembe, Miriam and Mulowooz, Jude and Santos, Nicole and Biemba, Godfrey and Herlihy, Julie M. and Mbewe, Reuben K. and Mweena, Fern and Yeboah‐Antwi, Kojo and Bruce, Jane and Chandramohan, Daniel and Prendergast, Andrew and Lawn, Joy E. and Blencowe, Hannah and Ohuma, Eric and Okwaraji, Yemi and Yargawa, Judith and Bradley, Ellen and Katz, Joanne and the Subnational Vulnerable Newborn Prevalence Collaborative Group and Vulnerable Newborn Measurement Core Group, [missing]}}, issn = {{1470-0328}}, journal = {{BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY}}, keywords = {{low birthweight,newborn,preterm birth,small for gestational age,FOR-GESTATIONAL-AGE,MIDDLE-INCOME COUNTRIES,MORTALITY,RISK,PRETERM,INFANTS,WEIGHT,TERM}}, language = {{eng}}, pages = {{1--17}}, title = {{Vulnerable newborn types : analysis of subnational, population‐based birth cohorts for 541 285 live births in 23 countries, 2000-2021}}, url = {{http://doi.org/10.1111/1471-0528.17510}}, year = {{2025}}, }
- Altmetric
- View in Altmetric
- Web of Science
- Times cited: