Adrenal insufficiency, be aware of drug interactions!
- Author
- Elke Thijs, Katrien Wierckx, Stefaan Vandecasteele and Annick Van den Bruel
- Organization
- Abstract
- A 42-year-old man with complaints of muscle soreness and an increased pigmentation of the skin was referred because of a suspicion of adrenal insufficiency. His adrenocorticotropic hormone and cortisol levels indicated a primary adrenal insufficiency (PAI) and treatment with hydrocortisone and fludrocortisone was initiated. An etiological workup, including an assessment for anti-adrenal antibodies, very long-chain fatty acids, 17-OH progesterone levels and catecholamine secretion, showed no abnormalities. (18)Fluorodeoxyglucose positron emission tomography/CT showed bilateral enlargement of the adrenal glands and bilateral presence of an adrenal nodule, with (18)fluorodeoxyglucose accumulation. A positive tuberculin test and positive family history of tuberculosis were found, and tuberculostatic drugs were initiated. During the treatment with the tuberculostatic drugs the patient again developed complaints of adrenal insufficiency, due to insufficient dosage of hydrocortisone because of increased metabolism of hydrocortisone.
- Keywords
- DIAGNOSIS
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-01GV54QVWV0PHSAS9X96VERBWP
- MLA
- Thijs, Elke, et al. “Adrenal Insufficiency, Be Aware of Drug Interactions!” ENDOCRINOLOGY DIABETES AND METABOLISM CASE REPORTS, vol. 2019, no. 1, 2019, doi:10.1530/EDM-19-0062.
- APA
- Thijs, E., Wierckx, K., Vandecasteele, S., & Van den Bruel, A. (2019). Adrenal insufficiency, be aware of drug interactions! ENDOCRINOLOGY DIABETES AND METABOLISM CASE REPORTS, 2019(1). https://doi.org/10.1530/EDM-19-0062
- Chicago author-date
- Thijs, Elke, Katrien Wierckx, Stefaan Vandecasteele, and Annick Van den Bruel. 2019. “Adrenal Insufficiency, Be Aware of Drug Interactions!” ENDOCRINOLOGY DIABETES AND METABOLISM CASE REPORTS 2019 (1). https://doi.org/10.1530/EDM-19-0062.
- Chicago author-date (all authors)
- Thijs, Elke, Katrien Wierckx, Stefaan Vandecasteele, and Annick Van den Bruel. 2019. “Adrenal Insufficiency, Be Aware of Drug Interactions!” ENDOCRINOLOGY DIABETES AND METABOLISM CASE REPORTS 2019 (1). doi:10.1530/EDM-19-0062.
- Vancouver
- 1.Thijs E, Wierckx K, Vandecasteele S, Van den Bruel A. Adrenal insufficiency, be aware of drug interactions! ENDOCRINOLOGY DIABETES AND METABOLISM CASE REPORTS. 2019;2019(1).
- IEEE
- [1]E. Thijs, K. Wierckx, S. Vandecasteele, and A. Van den Bruel, “Adrenal insufficiency, be aware of drug interactions!,” ENDOCRINOLOGY DIABETES AND METABOLISM CASE REPORTS, vol. 2019, no. 1, 2019.
@article{01GV54QVWV0PHSAS9X96VERBWP,
abstract = {{A 42-year-old man with complaints of muscle soreness and an increased pigmentation of the skin was referred because of a suspicion of adrenal insufficiency. His adrenocorticotropic hormone and cortisol levels indicated a primary adrenal insufficiency (PAI) and treatment with hydrocortisone and fludrocortisone was initiated. An etiological workup, including an assessment for anti-adrenal antibodies, very long-chain fatty acids, 17-OH progesterone levels and catecholamine secretion, showed no abnormalities. (18)Fluorodeoxyglucose positron emission tomography/CT showed bilateral enlargement of the adrenal glands and bilateral presence of an adrenal nodule, with (18)fluorodeoxyglucose accumulation. A positive tuberculin test and positive family history of tuberculosis were found, and tuberculostatic drugs were initiated. During the treatment with the tuberculostatic drugs the patient again developed complaints of adrenal insufficiency, due to insufficient dosage of hydrocortisone because of increased metabolism of hydrocortisone.}},
articleno = {{190062}},
author = {{Thijs, Elke and Wierckx, Katrien and Vandecasteele, Stefaan and Van den Bruel, Annick}},
issn = {{2052-0573}},
journal = {{ENDOCRINOLOGY DIABETES AND METABOLISM CASE REPORTS}},
keywords = {{DIAGNOSIS}},
language = {{eng}},
number = {{1}},
pages = {{4}},
title = {{Adrenal insufficiency, be aware of drug interactions!}},
url = {{http://doi.org/10.1530/EDM-19-0062}},
volume = {{2019}},
year = {{2019}},
}
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