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Can transcranial direct current stimulation (tDCS) of the cerebellum improve implicit social and cognitive sequence learning?

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Abstract
Accumulating evidence shows that the posterior cerebellum is involved in mentalizing inferences of social events by detecting sequence information in these events, and building and updating internal models of these sequences. By applying anodal and sham cerebellar transcranial direct current stimulation (tDCS) on the posteromedial cere-bellum of healthy participants, and using a serial reaction time (SRT) task paradigm, the current study examined the causal involvement of the cerebellum in implicitly learning sequences of social beliefs of others (Belief SRT) and non-social colored shapes (Cognitive SRT). Apart from the social or cognitive domain differences, both tasks were structurally identical. Results of anodal stimulation (i.e., 2 mA for 20 min) during the social Belief SRT task, did not show significant improvement in reaction times, however it did reveal generally faster responses for the Cognitive SRT task. This improved performance could also be observed after the cessation of stimulation after 30 min, and up to one week later. Our findings suggest a general positive effect of anodal cerebellar tDCS on implicit non-social Cognitive sequence learning, supporting a causal role of the cerebellum in this learning pro-cess. We speculate that the lack of tDCS modulation of the social Belief SRT task is due to the familiar and over -learned nature of attributing social beliefs, suggesting that easy and automatized tasks leave little room for improvement through tDCS.
Keywords
Clinical Psychology, Serial reaction time task (SRT), Cognitive sequencing, Social sequencing, Cerebellum, Brain stimulation, Transcranial direct current stimulation (tDCS)

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MLA
Ma, Qianying, et al. “Can Transcranial Direct Current Stimulation (TDCS) of the Cerebellum Improve Implicit Social and Cognitive Sequence Learning?” INTERNATIONAL JOURNAL OF CLINICAL AND HEALTH PSYCHOLOGY, vol. 23, no. 2, Elsevier BV, 2023, doi:10.1016/j.ijchp.2022.100355.
APA
Ma, Q., Pu, M., Li, M., Haihambo, N., Baetens, K., Heleven, E., … Van Overwalle, F. (2023). Can transcranial direct current stimulation (tDCS) of the cerebellum improve implicit social and cognitive sequence learning? INTERNATIONAL JOURNAL OF CLINICAL AND HEALTH PSYCHOLOGY, 23(2). https://doi.org/10.1016/j.ijchp.2022.100355
Chicago author-date
Ma, Qianying, Min Pu, Meijia Li, Naem Haihambo, Kris Baetens, Elien Heleven, Natacha Deroost, Chris Baeken, and Frank Van Overwalle. 2023. “Can Transcranial Direct Current Stimulation (TDCS) of the Cerebellum Improve Implicit Social and Cognitive Sequence Learning?” INTERNATIONAL JOURNAL OF CLINICAL AND HEALTH PSYCHOLOGY 23 (2). https://doi.org/10.1016/j.ijchp.2022.100355.
Chicago author-date (all authors)
Ma, Qianying, Min Pu, Meijia Li, Naem Haihambo, Kris Baetens, Elien Heleven, Natacha Deroost, Chris Baeken, and Frank Van Overwalle. 2023. “Can Transcranial Direct Current Stimulation (TDCS) of the Cerebellum Improve Implicit Social and Cognitive Sequence Learning?” INTERNATIONAL JOURNAL OF CLINICAL AND HEALTH PSYCHOLOGY 23 (2). doi:10.1016/j.ijchp.2022.100355.
Vancouver
1.
Ma Q, Pu M, Li M, Haihambo N, Baetens K, Heleven E, et al. Can transcranial direct current stimulation (tDCS) of the cerebellum improve implicit social and cognitive sequence learning? INTERNATIONAL JOURNAL OF CLINICAL AND HEALTH PSYCHOLOGY. 2023;23(2).
IEEE
[1]
Q. Ma et al., “Can transcranial direct current stimulation (tDCS) of the cerebellum improve implicit social and cognitive sequence learning?,” INTERNATIONAL JOURNAL OF CLINICAL AND HEALTH PSYCHOLOGY, vol. 23, no. 2, 2023.
@article{01GV084J8TAH4QA472FNRZKBP9,
  abstract     = {{Accumulating evidence shows that the posterior cerebellum is involved in mentalizing inferences of social events by detecting sequence information in these events, and building and updating internal models of these sequences. By applying anodal and sham cerebellar transcranial direct current stimulation (tDCS) on the posteromedial cere-bellum of healthy participants, and using a serial reaction time (SRT) task paradigm, the current study examined the causal involvement of the cerebellum in implicitly learning sequences of social beliefs of others (Belief SRT) and non-social colored shapes (Cognitive SRT). Apart from the social or cognitive domain differences, both tasks were structurally identical. Results of anodal stimulation (i.e., 2 mA for 20 min) during the social Belief SRT task, did not show significant improvement in reaction times, however it did reveal generally faster responses for the Cognitive SRT task. This improved performance could also be observed after the cessation of stimulation after 30 min, and up to one week later. Our findings suggest a general positive effect of anodal cerebellar tDCS on implicit non-social Cognitive sequence learning, supporting a causal role of the cerebellum in this learning pro-cess. We speculate that the lack of tDCS modulation of the social Belief SRT task is due to the familiar and over -learned nature of attributing social beliefs, suggesting that easy and automatized tasks leave little room for improvement through tDCS.}},
  articleno    = {{100355}},
  author       = {{Ma, Qianying and Pu, Min and Li, Meijia and Haihambo, Naem and Baetens, Kris and Heleven, Elien and Deroost, Natacha and Baeken, Chris and Van Overwalle, Frank}},
  issn         = {{1697-2600}},
  journal      = {{INTERNATIONAL JOURNAL OF CLINICAL AND HEALTH PSYCHOLOGY}},
  keywords     = {{Clinical Psychology,Serial reaction time task (SRT),Cognitive sequencing,Social sequencing,Cerebellum,Brain stimulation,Transcranial direct current stimulation (tDCS)}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{11}},
  publisher    = {{Elsevier BV}},
  title        = {{Can transcranial direct current stimulation (tDCS) of the cerebellum improve implicit social and cognitive sequence learning?}},
  url          = {{http://doi.org/10.1016/j.ijchp.2022.100355}},
  volume       = {{23}},
  year         = {{2023}},
}

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