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The increasing significance of disease severity in a burden of disease framework

Grant M.A. Wyper, Ricardo Assuncao, Eilidh Fletcher, Michelle Gourley, Ian Grant, Juanita A. Haagsma, Henk Hilderink, Jane Idavain, Tina Lesnik, Elena von der Lippe, et al.
(2023) SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 51(2). p.296-300
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Abstract
Recent estimates have reiterated that non-fatal causes of disease, such as low back pain, headaches and depressive disorders, are amongst the leading causes of disability-adjusted life years (DALYs). For these causes, the contribution of years lived with disability (YLD) - put simply, ill-health - is what drives DALYs, not mortality. Being able to monitor trends in YLD closely is particularly relevant for countries that sit high on the socio-demographic spectrum of development, as it contributes more than half of all DALYs. There is a paucity of data on how the population-level occurrence of disease is distributed according to severity, and as such, the majority of global and national efforts in monitoring YLD lack the ability to differentiate changes in severity across time and location. This raises uncertainties in interpreting these findings without triangulation with other relevant data sources. Our commentary aims to bring this issue to the forefront for users of burden of disease estimates, as its impact is often easily overlooked as part of the fundamental process of generating DALY estimates. Moreover, the wider health harms of the COVID-19 pandemic have underlined the likelihood of latent and delayed demand in accessing vital health and care services that will ultimately lead to exacerbated disease severity and health outcomes. This places increased importance on attempts to be able to differentiate by both the occurrence and severity of disease.
Keywords
burden of disease, severity distribution, European burden of disease network, disease severity, Scottish burden of disease

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MLA
Wyper, Grant M. A., et al. “The Increasing Significance of Disease Severity in a Burden of Disease Framework.” SCANDINAVIAN JOURNAL OF PUBLIC HEALTH, vol. 51, no. 2, SAGE Publications, 2023, pp. 296–300, doi:10.1177/14034948211024478.
APA
Wyper, G. M. A., Assuncao, R., Fletcher, E., Gourley, M., Grant, I., Haagsma, J. A., … Devleesschauwer, B. (2023). The increasing significance of disease severity in a burden of disease framework. https://doi.org/10.1177/14034948211024478
Chicago author-date
Wyper, Grant M.A., Ricardo Assuncao, Eilidh Fletcher, Michelle Gourley, Ian Grant, Juanita A. Haagsma, Henk Hilderink, et al. 2023. “The Increasing Significance of Disease Severity in a Burden of Disease Framework.” SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. SAGE Publications. https://doi.org/10.1177/14034948211024478.
Chicago author-date (all authors)
Wyper, Grant M.A., Ricardo Assuncao, Eilidh Fletcher, Michelle Gourley, Ian Grant, Juanita A. Haagsma, Henk Hilderink, Jane Idavain, Tina Lesnik, Elena von der Lippe, Marek Majdan, Gerry Mccartney, Milena Santric-Milicevic, Elena Pallari, Sara M. Pires, Dietrich Plass, Michael Porst, João V. Santos, Maria Teresa de Haro Moro, Diane L. Stockton, and Brecht Devleesschauwer. 2023. “The Increasing Significance of Disease Severity in a Burden of Disease Framework.” SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. SAGE Publications. doi:10.1177/14034948211024478.
Vancouver
1.
Wyper GMA, Assuncao R, Fletcher E, Gourley M, Grant I, Haagsma JA, et al. The increasing significance of disease severity in a burden of disease framework. Vol. 51, SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. SAGE Publications; 2023. p. 296–300.
IEEE
[1]
G. M. A. Wyper et al., “The increasing significance of disease severity in a burden of disease framework,” SCANDINAVIAN JOURNAL OF PUBLIC HEALTH, vol. 51, no. 2. SAGE Publications, pp. 296–300, 2023.
@misc{01GTSNFMFF2GK3WK8RM342XT6V,
  abstract     = {{Recent estimates have reiterated that non-fatal causes of disease, such as low back pain, headaches and depressive disorders, are amongst the leading causes of disability-adjusted life years (DALYs). For these causes, the contribution of years lived with disability (YLD) - put simply, ill-health - is what drives DALYs, not mortality. Being able to monitor trends in YLD closely is particularly relevant for countries that sit high on the socio-demographic spectrum of development, as it contributes more than half of all DALYs. There is a paucity of data on how the population-level occurrence of disease is distributed according to severity, and as such, the majority of global and national efforts in monitoring YLD lack the ability to differentiate changes in severity across time and location. This raises uncertainties in interpreting these findings without triangulation with other relevant data sources. Our commentary aims to bring this issue to the forefront for users of burden of disease estimates, as its impact is often easily overlooked as part of the fundamental process of generating DALY estimates. Moreover, the wider health harms of the COVID-19 pandemic have underlined the likelihood of latent and delayed demand in accessing vital health and care services that will ultimately lead to exacerbated disease severity and health outcomes. This places increased importance on attempts to be able to differentiate by both the occurrence and severity of disease.}},
  articleno    = {{14034948211024478}},
  author       = {{Wyper, Grant M.A. and Assuncao, Ricardo and Fletcher, Eilidh and Gourley, Michelle and Grant, Ian and Haagsma, Juanita A. and Hilderink, Henk and Idavain, Jane and Lesnik, Tina and von der Lippe, Elena and Majdan, Marek and Mccartney, Gerry and Santric-Milicevic, Milena and Pallari, Elena and Pires, Sara M. and Plass, Dietrich and Porst, Michael and Santos, João V. and de Haro Moro, Maria Teresa and Stockton, Diane L. and Devleesschauwer, Brecht}},
  issn         = {{1403-4948}},
  keywords     = {{burden of disease,severity distribution,European burden of disease network,disease severity,Scottish burden of disease}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{14034948211024478:296--14034948211024478:300}},
  publisher    = {{SAGE Publications}},
  series       = {{SCANDINAVIAN JOURNAL OF PUBLIC HEALTH}},
  title        = {{The increasing significance of disease severity in a burden of disease framework}},
  url          = {{http://doi.org/10.1177/14034948211024478}},
  volume       = {{51}},
  year         = {{2023}},
}
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