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Lay rescuer use of automated external defibrillators in infants, children and adolescents : a systematic review

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Abstract
Importance: Automated external defibrillator (AED) use is increasing, but use in children is uncommon. A growing literature of use in children by lay rescuers warrants review. Objective: A systematic review of AED effectiveness in children experiencing out-of-hospital cardiac arrest (OHCA). Data Sources: PubMed, EMBASE, Cochrane Register of Controlled Trials. Study Selection: Children, ages 0-18, experiencing OHCA with an AED applied by a lay rescuer. Control population: children with no AED application. Data Extraction and Synthesis: Results are reported according to PRISMA guidelines. Two authors independently reviewed all titles and abstracts of references identified by the search strategy, then generated a subset which all authors reviewed. Main Outcomes and Measures: Critical outcomes were survival with Cerebral Performance Category (CPC) 1-2 at hospital discharge or 30 days and survival to hospital discharge. Results: Population: age categories: <1 year, 1-12 years, 13-18 years. Lay rescuer AED application resulted in improved survival with CPC 1-2 at hospital discharge or 30 days to hospital discharge in age groups 1-12 and 13-18 years (RR 3.84 [95 % CI 2.69-5.5], RR 3.75 [95 %CI 2.97-4.72]), respectively and hospital discharge in both groups(RR 3.04 [95 % CI 2.18-4.25], RR 3.38 [95 % CI 2.17-4.16]), respectively. AED use with CPR improved CPC 1-2 at hospital discharge and hospital discharge (RR 1.49 [95 % CI 1.11-1.97], RR 1.55[1.12-2.12]). Conclusions: AED application by lay rescuers is associated with improved survival with a CPC of 1-2 at 30 days, and improved survival to hospital discharge for children 1-18 years. There are limited data for children < 1 year.
Keywords
Public access defibrillation, Out-of-hospital cardiac arrest, Defibrillation, Cardiopulmonary resuscitation, Adolescent, Children

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MLA
Atkins, Dianne L., et al. “Lay Rescuer Use of Automated External Defibrillators in Infants, Children and Adolescents : A Systematic Review.” RESUSCITATION PLUS, vol. 11, Elsevier BV, 2022, doi:10.1016/j.resplu.2022.100283.
APA
Atkins, D. L., Acworth, J., Chung, S. P., Reis, A., Van de Voorde, P., & Pediatric and Basic Life Support Task Forces, I. L. C. on R. (ILCOR). (2022). Lay rescuer use of automated external defibrillators in infants, children and adolescents : a systematic review. RESUSCITATION PLUS, 11. https://doi.org/10.1016/j.resplu.2022.100283
Chicago author-date
Atkins, Dianne L., Jason Acworth, Sung Phil Chung, Amelia Reis, Patrick Van de Voorde, and International Liaison Committee on Resuscitation (ILCOR) Pediatric and Basic Life Support Task Forces. 2022. “Lay Rescuer Use of Automated External Defibrillators in Infants, Children and Adolescents : A Systematic Review.” RESUSCITATION PLUS 11. https://doi.org/10.1016/j.resplu.2022.100283.
Chicago author-date (all authors)
Atkins, Dianne L., Jason Acworth, Sung Phil Chung, Amelia Reis, Patrick Van de Voorde, and International Liaison Committee on Resuscitation (ILCOR) Pediatric and Basic Life Support Task Forces. 2022. “Lay Rescuer Use of Automated External Defibrillators in Infants, Children and Adolescents : A Systematic Review.” RESUSCITATION PLUS 11. doi:10.1016/j.resplu.2022.100283.
Vancouver
1.
Atkins DL, Acworth J, Chung SP, Reis A, Van de Voorde P, Pediatric and Basic Life Support Task Forces ILC on R (ILCOR). Lay rescuer use of automated external defibrillators in infants, children and adolescents : a systematic review. RESUSCITATION PLUS. 2022;11.
IEEE
[1]
D. L. Atkins, J. Acworth, S. P. Chung, A. Reis, P. Van de Voorde, and I. L. C. on R. (ILCOR) Pediatric and Basic Life Support Task Forces, “Lay rescuer use of automated external defibrillators in infants, children and adolescents : a systematic review,” RESUSCITATION PLUS, vol. 11, 2022.
@article{01GTERGBGP88N410E5NCXHMEFR,
  abstract     = {{Importance: Automated external defibrillator (AED) use is increasing, but use in children is uncommon. A growing literature of use in children by lay rescuers warrants review.

Objective: A systematic review of AED effectiveness in children experiencing out-of-hospital cardiac arrest (OHCA).

Data Sources: PubMed, EMBASE, Cochrane Register of Controlled Trials.

Study Selection: Children, ages 0-18, experiencing OHCA with an AED applied by a lay rescuer. Control population: children with no AED application.

Data Extraction and Synthesis: Results are reported according to PRISMA guidelines. Two authors independently reviewed all titles and abstracts of references identified by the search strategy, then generated a subset which all authors reviewed.

Main Outcomes and Measures: Critical outcomes were survival with Cerebral Performance Category (CPC) 1-2 at hospital discharge or 30 days and survival to hospital discharge.

Results: Population: age categories: <1 year, 1-12 years, 13-18 years. Lay rescuer AED application resulted in improved survival with CPC 1-2 at hospital discharge or 30 days to hospital discharge in age groups 1-12 and 13-18 years (RR 3.84 [95 % CI 2.69-5.5], RR 3.75 [95 %CI 2.97-4.72]), respectively and hospital discharge in both groups(RR 3.04 [95 % CI 2.18-4.25], RR 3.38 [95 % CI 2.17-4.16]), respectively. AED use with CPR improved CPC 1-2 at hospital discharge and hospital discharge (RR 1.49 [95 % CI 1.11-1.97], RR 1.55[1.12-2.12]).

Conclusions: AED application by lay rescuers is associated with improved survival with a CPC of 1-2 at 30 days, and improved survival to hospital discharge for children 1-18 years. There are limited data for children < 1 year.}},
  articleno    = {{100283}},
  author       = {{Atkins, Dianne L. and Acworth, Jason and Chung, Sung Phil and Reis, Amelia and Van de Voorde, Patrick and Pediatric and Basic Life Support Task Forces, International Liaison Committee on Resuscitation (ILCOR)}},
  issn         = {{2666-5204}},
  journal      = {{RESUSCITATION PLUS}},
  keywords     = {{Public access defibrillation,Out-of-hospital cardiac arrest,Defibrillation,Cardiopulmonary resuscitation,Adolescent,Children}},
  language     = {{eng}},
  pages        = {{8}},
  publisher    = {{Elsevier BV}},
  title        = {{Lay rescuer use of automated external defibrillators in infants, children and adolescents : a systematic review}},
  url          = {{http://doi.org/10.1016/j.resplu.2022.100283}},
  volume       = {{11}},
  year         = {{2022}},
}

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