Engineering the plant metabolic system by exploiting metabolic regulation
- Author
- Sara Selma Garcia (UGent) , Nikolaos Ntelkis (UGent) , Trang Hieu Nguyen (UGent) and Alain Goossens (UGent)
- Organization
- Project
- Abstract
- Plants are the most sophisticated biofactories and sources of food and biofuels present in nature. By engineering plant metabolism, the production of desired compounds can be increased and the nutritional or commercial value of the plant species can be improved. However, this can be challenging because of the complexity of the regulation of multiple genes and the involvement of different protein interactions. To improve metabolic engineering (ME) capabilities, different tools and strategies for rerouting the metabolic pathways have been developed, including genome editing and transcriptional regulation approaches. In addition, cutting-edge technologies have provided new methods for understanding uncharacterized biosynthetic pathways, protein degradation mechanisms, protein-protein interactions, or allosteric feedback, enabling the design of novel ME approaches.
- Keywords
- CRISPR/Cas, interactomics, plant production platforms, posttranslational modification, subcellular organelles, transcription factors.
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-01GST7MPHHCW0T7DWFMQX1F9W0
- MLA
- Selma Garcia, Sara, et al. “Engineering the Plant Metabolic System by Exploiting Metabolic Regulation.” PLANT JOURNAL, vol. 114, no. 5, 2023, pp. 1149–63, doi:10.1111/tpj.16157.
- APA
- Selma Garcia, S., Ntelkis, N., Nguyen, T. H., & Goossens, A. (2023). Engineering the plant metabolic system by exploiting metabolic regulation. PLANT JOURNAL, 114(5), 1149–1163. https://doi.org/10.1111/tpj.16157
- Chicago author-date
- Selma Garcia, Sara, Nikolaos Ntelkis, Trang Hieu Nguyen, and Alain Goossens. 2023. “Engineering the Plant Metabolic System by Exploiting Metabolic Regulation.” PLANT JOURNAL 114 (5): 1149–63. https://doi.org/10.1111/tpj.16157.
- Chicago author-date (all authors)
- Selma Garcia, Sara, Nikolaos Ntelkis, Trang Hieu Nguyen, and Alain Goossens. 2023. “Engineering the Plant Metabolic System by Exploiting Metabolic Regulation.” PLANT JOURNAL 114 (5): 1149–1163. doi:10.1111/tpj.16157.
- Vancouver
- 1.Selma Garcia S, Ntelkis N, Nguyen TH, Goossens A. Engineering the plant metabolic system by exploiting metabolic regulation. PLANT JOURNAL. 2023;114(5):1149–63.
- IEEE
- [1]S. Selma Garcia, N. Ntelkis, T. H. Nguyen, and A. Goossens, “Engineering the plant metabolic system by exploiting metabolic regulation,” PLANT JOURNAL, vol. 114, no. 5, pp. 1149–1163, 2023.
@article{01GST7MPHHCW0T7DWFMQX1F9W0,
abstract = {{Plants are the most sophisticated biofactories and sources of food and biofuels present in nature. By engineering plant metabolism, the production of desired compounds can be increased and the nutritional or commercial value of the plant species can be improved. However, this can be challenging because of the complexity of the regulation of multiple genes and the involvement of different protein interactions. To improve metabolic engineering (ME) capabilities, different tools and strategies for rerouting the metabolic pathways have been developed, including genome editing and transcriptional regulation approaches. In addition, cutting-edge technologies have provided new methods for understanding uncharacterized biosynthetic pathways, protein degradation mechanisms, protein-protein interactions, or allosteric feedback, enabling the design of novel ME approaches.}},
author = {{Selma Garcia, Sara and Ntelkis, Nikolaos and Nguyen, Trang Hieu and Goossens, Alain}},
issn = {{0960-7412}},
journal = {{PLANT JOURNAL}},
keywords = {{CRISPR/Cas,interactomics,plant production platforms,posttranslational modification,subcellular organelles,transcription factors.}},
language = {{eng}},
number = {{5}},
pages = {{1149--1163}},
title = {{Engineering the plant metabolic system by exploiting metabolic regulation}},
url = {{http://doi.org/10.1111/tpj.16157}},
volume = {{114}},
year = {{2023}},
}
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