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Efficacy of interdisciplinary rehabilitation in child cancer survivors : impact on physical fitness, fatigue and body composition after 1‐year follow‐up

Ruth Van der Looven (UGent) , Elise De Vos (UGent) , Kristof Vandekerckhove (UGent) , Ilse Coomans (UGent) , Genevieve Laureys (UGent) and Catharina Dhooge (UGent)
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Abstract
Objective Childhood cancer survivors experience reduced physical activity level, participation as well as health-related quality of life. This prospective, pre-/post-intervention and follow-up cohort study aims to determine the efficacy of an interdisciplinary rehabilitation on improving physical fitness, fatigue and body composition. Methods A total of 24 childhood cancer survivors (mean age: 12.15 years +/- 3.2; 14 females; 10 males) were recruited 6 months after medical treatment and received a 4-month interdisciplinary intervention. Cardiorespiratory fitness (PredVO(2peak) and PredLoad(max)), body composition (dry lean weight) and quality of life (general fatigue) were assessed at baseline, post-intervention and 1-year follow-up. Linear mixed models were used to analyse data. Results Linear mixed modelling revealed a significant main effect of time on predicted maximal load (F = 13.189, df = 36.179, p < 0.001), dry lean weight (F = 64.813, df = 37.019, p < 0.001) but also significant improvement of general fatigue score (-9.039 +/- 4.300, 95% CI -17.741 to -0.336, p = 0.042), indicating a decline in general fatigue. Conclusion With emerging evidence that physical activity is safe and feasible, together with increasing numbers of childhood cancer survivors at risk for long-term chronic co-morbidities, this study advocates for better access to interdisciplinary rehabilitation programmes in order to improve their physical condition and their body composition and reduce fatigue.
Keywords
Oncology, physical fitness, long-term chronic co-morbidities, interdisciplinary rehabilitation, fatigue, childhood cancer survivors, body composition

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MLA
Van der Looven, Ruth, et al. “Efficacy of Interdisciplinary Rehabilitation in Child Cancer Survivors : Impact on Physical Fitness, Fatigue and Body Composition after 1‐year Follow‐up.” EUROPEAN JOURNAL OF CANCER CARE, vol. 31, no. 6, Hindawi Limited, 2022, doi:10.1111/ecc.13761.
APA
Van der Looven, R., De Vos, E., Vandekerckhove, K., Coomans, I., Laureys, G., & Dhooge, C. (2022). Efficacy of interdisciplinary rehabilitation in child cancer survivors : impact on physical fitness, fatigue and body composition after 1‐year follow‐up. EUROPEAN JOURNAL OF CANCER CARE, 31(6). https://doi.org/10.1111/ecc.13761
Chicago author-date
Van der Looven, Ruth, Elise De Vos, Kristof Vandekerckhove, Ilse Coomans, Genevieve Laureys, and Catharina Dhooge. 2022. “Efficacy of Interdisciplinary Rehabilitation in Child Cancer Survivors : Impact on Physical Fitness, Fatigue and Body Composition after 1‐year Follow‐up.” EUROPEAN JOURNAL OF CANCER CARE 31 (6). https://doi.org/10.1111/ecc.13761.
Chicago author-date (all authors)
Van der Looven, Ruth, Elise De Vos, Kristof Vandekerckhove, Ilse Coomans, Genevieve Laureys, and Catharina Dhooge. 2022. “Efficacy of Interdisciplinary Rehabilitation in Child Cancer Survivors : Impact on Physical Fitness, Fatigue and Body Composition after 1‐year Follow‐up.” EUROPEAN JOURNAL OF CANCER CARE 31 (6). doi:10.1111/ecc.13761.
Vancouver
1.
Van der Looven R, De Vos E, Vandekerckhove K, Coomans I, Laureys G, Dhooge C. Efficacy of interdisciplinary rehabilitation in child cancer survivors : impact on physical fitness, fatigue and body composition after 1‐year follow‐up. EUROPEAN JOURNAL OF CANCER CARE. 2022;31(6).
IEEE
[1]
R. Van der Looven, E. De Vos, K. Vandekerckhove, I. Coomans, G. Laureys, and C. Dhooge, “Efficacy of interdisciplinary rehabilitation in child cancer survivors : impact on physical fitness, fatigue and body composition after 1‐year follow‐up,” EUROPEAN JOURNAL OF CANCER CARE, vol. 31, no. 6, 2022.
@article{01GPZXZ7QWJMDMDSK80763Q0PG,
  abstract     = {{Objective Childhood cancer survivors experience reduced physical activity level, participation as well as health-related quality of life. This prospective, pre-/post-intervention and follow-up cohort study aims to determine the efficacy of an interdisciplinary rehabilitation on improving physical fitness, fatigue and body composition. Methods A total of 24 childhood cancer survivors (mean age: 12.15 years +/- 3.2; 14 females; 10 males) were recruited 6 months after medical treatment and received a 4-month interdisciplinary intervention. Cardiorespiratory fitness (PredVO(2peak) and PredLoad(max)), body composition (dry lean weight) and quality of life (general fatigue) were assessed at baseline, post-intervention and 1-year follow-up. Linear mixed models were used to analyse data. Results Linear mixed modelling revealed a significant main effect of time on predicted maximal load (F = 13.189, df = 36.179, p < 0.001), dry lean weight (F = 64.813, df = 37.019, p < 0.001) but also significant improvement of general fatigue score (-9.039 +/- 4.300, 95% CI -17.741 to -0.336, p = 0.042), indicating a decline in general fatigue. Conclusion With emerging evidence that physical activity is safe and feasible, together with increasing numbers of childhood cancer survivors at risk for long-term chronic co-morbidities, this study advocates for better access to interdisciplinary rehabilitation programmes in order to improve their physical condition and their body composition and reduce fatigue.}},
  articleno    = {{e13761}},
  author       = {{Van der Looven, Ruth and De Vos, Elise and Vandekerckhove, Kristof and Coomans, Ilse and Laureys, Genevieve and Dhooge, Catharina}},
  issn         = {{0961-5423}},
  journal      = {{EUROPEAN JOURNAL OF CANCER CARE}},
  keywords     = {{Oncology,physical fitness,long-term chronic co-morbidities,interdisciplinary rehabilitation,fatigue,childhood cancer survivors,body composition}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{11}},
  publisher    = {{Hindawi Limited}},
  title        = {{Efficacy of interdisciplinary rehabilitation in child cancer survivors : impact on physical fitness, fatigue and body composition after 1‐year follow‐up}},
  url          = {{http://doi.org/10.1111/ecc.13761}},
  volume       = {{31}},
  year         = {{2022}},
}

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