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Exciting times for lipid nanoparticles : how Canadian discoveries are enabling gene therapies

(2022) MOLECULAR PHARMACEUTICS. 19(6). p.1663-1668
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Abstract
In this brief perspective, we describe key events in the history of the lipid-based nanomedicine field, highlight Canadian contributions, and outline areas where lipid nanoparticle technology is poised to have a transformative effect on the future of medicine.
Keywords
Drug Discovery, Pharmaceutical Science, Molecular Medicine, lipid nanoparticles, gene therapy, mRNA, vaccines, CAR-T therapy, CRISPR-Cas9, LARGE UNILAMELLAR VESICLES, MESSENGER-RNA VACCINES, IN-VIVO, LIPOSOMES, PCSK9, SIRNA, CHOLESTEROL, PROTECTION, DRUGS, LDL

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Citation

Please use this url to cite or link to this publication:

MLA
Cheng, Miffy H. Y., et al. “Exciting Times for Lipid Nanoparticles : How Canadian Discoveries Are Enabling Gene Therapies.” MOLECULAR PHARMACEUTICS, vol. 19, no. 6, 2022, pp. 1663–68, doi:10.1021/acs.molpharmaceut.2c00365.
APA
Cheng, M. H. Y., Brimacombe, C. A., Verbeke, R., & Cullis, P. R. (2022). Exciting times for lipid nanoparticles : how Canadian discoveries are enabling gene therapies. MOLECULAR PHARMACEUTICS, 19(6), 1663–1668. https://doi.org/10.1021/acs.molpharmaceut.2c00365
Chicago author-date
Cheng, Miffy H. Y., Cedric A. Brimacombe, Rein Verbeke, and Pieter R. Cullis. 2022. “Exciting Times for Lipid Nanoparticles : How Canadian Discoveries Are Enabling Gene Therapies.” MOLECULAR PHARMACEUTICS 19 (6): 1663–68. https://doi.org/10.1021/acs.molpharmaceut.2c00365.
Chicago author-date (all authors)
Cheng, Miffy H. Y., Cedric A. Brimacombe, Rein Verbeke, and Pieter R. Cullis. 2022. “Exciting Times for Lipid Nanoparticles : How Canadian Discoveries Are Enabling Gene Therapies.” MOLECULAR PHARMACEUTICS 19 (6): 1663–1668. doi:10.1021/acs.molpharmaceut.2c00365.
Vancouver
1.
Cheng MHY, Brimacombe CA, Verbeke R, Cullis PR. Exciting times for lipid nanoparticles : how Canadian discoveries are enabling gene therapies. MOLECULAR PHARMACEUTICS. 2022;19(6):1663–8.
IEEE
[1]
M. H. Y. Cheng, C. A. Brimacombe, R. Verbeke, and P. R. Cullis, “Exciting times for lipid nanoparticles : how Canadian discoveries are enabling gene therapies,” MOLECULAR PHARMACEUTICS, vol. 19, no. 6, pp. 1663–1668, 2022.
@article{01GM25MB0PQF7FSTRTBVC93QMT,
  abstract     = {{In this brief perspective, we describe key events in the history of the lipid-based nanomedicine field, highlight Canadian contributions, and outline areas where lipid nanoparticle technology is poised to have a transformative effect on the future of medicine.}},
  author       = {{Cheng, Miffy H. Y. and Brimacombe, Cedric A. and Verbeke, Rein and Cullis, Pieter R.}},
  issn         = {{1543-8384}},
  journal      = {{MOLECULAR PHARMACEUTICS}},
  keywords     = {{Drug Discovery,Pharmaceutical Science,Molecular Medicine,lipid nanoparticles,gene therapy,mRNA,vaccines,CAR-T therapy,CRISPR-Cas9,LARGE UNILAMELLAR VESICLES,MESSENGER-RNA VACCINES,IN-VIVO,LIPOSOMES,PCSK9,SIRNA,CHOLESTEROL,PROTECTION,DRUGS,LDL}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{1663--1668}},
  title        = {{Exciting times for lipid nanoparticles : how Canadian discoveries are enabling gene therapies}},
  url          = {{http://doi.org/10.1021/acs.molpharmaceut.2c00365}},
  volume       = {{19}},
  year         = {{2022}},
}

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