Cysteine thiol–based post-translational modification : what do we know about transcription factors?
- Author
- Heng Zhou, Jingjing Huang (UGent) , Patrick Willems (UGent) , Frank Van Breusegem (UGent) and Yanjie Xie
- Organization
- Project
- Abstract
- Reactive electrophilic species are ubiquitous in plant cells, where they contribute to specific redox-regulated signaling events. Redox signaling is known to modulate gene expression during diverse biological processes, including plant growth, development, and environmental stress responses. Emerging data demonstrates that transcription factors (TFs) are a main target of cysteine thiol-based oxidative post-translational modifications (OxiPTMs), which can alter their transcriptional activity and thereby convey redox information to the nucleus. Here, we review the significant progress that has been made in characterizing cysteine thiol-based OxiPTMs, their biochemical properties, and their functional effects on plant TFs. We discuss the underlying mechanism of redox regulation and its contribution to various physiological processes as well as still outstanding challenges in redox regulation of plant gene expression.
- Keywords
- redox, plant, post-translational modifications, transcription factors
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-01GKTT3MAVBXAFVF07193ZBVZH
- MLA
- Zhou, Heng, et al. “Cysteine Thiol–Based Post-Translational Modification : What Do We Know about Transcription Factors?” TRENDS IN PLANT SCIENCE, vol. 28, no. 4, 2023, pp. 415–28, doi:10.1016/j.tplants.2022.11.007.
- APA
- Zhou, H., Huang, J., Willems, P., Van Breusegem, F., & Xie, Y. (2023). Cysteine thiol–based post-translational modification : what do we know about transcription factors? TRENDS IN PLANT SCIENCE, 28(4), 415–428. https://doi.org/10.1016/j.tplants.2022.11.007
- Chicago author-date
- Zhou, Heng, Jingjing Huang, Patrick Willems, Frank Van Breusegem, and Yanjie Xie. 2023. “Cysteine Thiol–Based Post-Translational Modification : What Do We Know about Transcription Factors?” TRENDS IN PLANT SCIENCE 28 (4): 415–28. https://doi.org/10.1016/j.tplants.2022.11.007.
- Chicago author-date (all authors)
- Zhou, Heng, Jingjing Huang, Patrick Willems, Frank Van Breusegem, and Yanjie Xie. 2023. “Cysteine Thiol–Based Post-Translational Modification : What Do We Know about Transcription Factors?” TRENDS IN PLANT SCIENCE 28 (4): 415–428. doi:10.1016/j.tplants.2022.11.007.
- Vancouver
- 1.Zhou H, Huang J, Willems P, Van Breusegem F, Xie Y. Cysteine thiol–based post-translational modification : what do we know about transcription factors? TRENDS IN PLANT SCIENCE. 2023;28(4):415–28.
- IEEE
- [1]H. Zhou, J. Huang, P. Willems, F. Van Breusegem, and Y. Xie, “Cysteine thiol–based post-translational modification : what do we know about transcription factors?,” TRENDS IN PLANT SCIENCE, vol. 28, no. 4, pp. 415–428, 2023.
@article{01GKTT3MAVBXAFVF07193ZBVZH,
abstract = {{Reactive electrophilic species are ubiquitous in plant cells, where they contribute to specific redox-regulated signaling events. Redox signaling is known to modulate gene expression during diverse biological processes, including plant growth, development, and environmental stress responses. Emerging data demonstrates that transcription factors (TFs) are a main target of cysteine thiol-based oxidative post-translational modifications (OxiPTMs), which can alter their transcriptional activity and thereby convey redox information to the nucleus. Here, we review the significant progress that has been made in characterizing cysteine thiol-based OxiPTMs, their biochemical properties, and their functional effects on plant TFs. We discuss the underlying mechanism of redox regulation and its contribution to various physiological processes as well as still outstanding challenges in redox regulation of plant gene expression.}},
author = {{Zhou, Heng and Huang, Jingjing and Willems, Patrick and Van Breusegem, Frank and Xie, Yanjie}},
issn = {{1360-1385}},
journal = {{TRENDS IN PLANT SCIENCE}},
keywords = {{redox,plant,post-translational modifications,transcription factors}},
language = {{eng}},
number = {{4}},
pages = {{415--428}},
title = {{Cysteine thiol–based post-translational modification : what do we know about transcription factors?}},
url = {{http://doi.org/10.1016/j.tplants.2022.11.007}},
volume = {{28}},
year = {{2023}},
}
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