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High-grade endometrial stromal sarcoma-like sarcoma in male : does it exist? A case report and review of the literature

Fleur Cordier (UGent) , Joni Van der Meulen (UGent) , Siebe Loontiens (UGent) , Nadine Van Roy (UGent) , Lore Lapeire (UGent) , Wouter Willaert (UGent) , Liesbeth Ferdinande (UGent) , Koen Van de Vijver (UGent) , Jo Van Dorpe (UGent) and David Creytens (UGent)
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Abstract
We report an exceptional case of an undifferentiated round and spindle cell sarcoma, occurring in the periprostatic region of a 54-year-old male, with a `high-grade endometrial stromal sarcoma-like' (HG-ESS) morphology and harboring a ZC3H7B::BCOR gene fusion identified by RNA-based next-generation sequencing. In this report, we describe the striking overlap of morphologic, immunohistochemical and molecular features of this current case and previously reported similar cases with ZC3H7B::BCOR fusion-positive HG-ESS, and discuss the differential diagnosis and possible pathogenesis of this unusual entity.
Keywords
Cell Biology, Pathology and Forensic Medicine, RNA-based next generation sequencing, High-grade endometrial stromal sarcoma, Undifferentiated sarcoma, Sarcoma with BCOR genetic alterations

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MLA
Cordier, Fleur, et al. “High-Grade Endometrial Stromal Sarcoma-like Sarcoma in Male : Does It Exist? A Case Report and Review of the Literature.” PATHOLOGY RESEARCH AND PRACTICE, vol. 241, Elsevier BV, 2023, doi:10.1016/j.prp.2022.154228.
APA
Cordier, F., Van der Meulen, J., Loontiens, S., Van Roy, N., Lapeire, L., Willaert, W., … Creytens, D. (2023). High-grade endometrial stromal sarcoma-like sarcoma in male : does it exist? A case report and review of the literature. PATHOLOGY RESEARCH AND PRACTICE, 241. https://doi.org/10.1016/j.prp.2022.154228
Chicago author-date
Cordier, Fleur, Joni Van der Meulen, Siebe Loontiens, Nadine Van Roy, Lore Lapeire, Wouter Willaert, Liesbeth Ferdinande, Koen Van de Vijver, Jo Van Dorpe, and David Creytens. 2023. “High-Grade Endometrial Stromal Sarcoma-like Sarcoma in Male : Does It Exist? A Case Report and Review of the Literature.” PATHOLOGY RESEARCH AND PRACTICE 241. https://doi.org/10.1016/j.prp.2022.154228.
Chicago author-date (all authors)
Cordier, Fleur, Joni Van der Meulen, Siebe Loontiens, Nadine Van Roy, Lore Lapeire, Wouter Willaert, Liesbeth Ferdinande, Koen Van de Vijver, Jo Van Dorpe, and David Creytens. 2023. “High-Grade Endometrial Stromal Sarcoma-like Sarcoma in Male : Does It Exist? A Case Report and Review of the Literature.” PATHOLOGY RESEARCH AND PRACTICE 241. doi:10.1016/j.prp.2022.154228.
Vancouver
1.
Cordier F, Van der Meulen J, Loontiens S, Van Roy N, Lapeire L, Willaert W, et al. High-grade endometrial stromal sarcoma-like sarcoma in male : does it exist? A case report and review of the literature. PATHOLOGY RESEARCH AND PRACTICE. 2023;241.
IEEE
[1]
F. Cordier et al., “High-grade endometrial stromal sarcoma-like sarcoma in male : does it exist? A case report and review of the literature,” PATHOLOGY RESEARCH AND PRACTICE, vol. 241, 2023.
@article{01GJF0BVTFBWWAY38SWR4TWR0J,
  abstract     = {{We report an exceptional case of an undifferentiated round and spindle cell sarcoma, occurring in the periprostatic region of a 54-year-old male, with a `high-grade endometrial stromal sarcoma-like' (HG-ESS) morphology and harboring a ZC3H7B::BCOR gene fusion identified by RNA-based next-generation sequencing. In this report, we describe the striking overlap of morphologic, immunohistochemical and molecular features of this current case and previously reported similar cases with ZC3H7B::BCOR fusion-positive HG-ESS, and discuss the differential diagnosis and possible pathogenesis of this unusual entity.}},
  articleno    = {{154228}},
  author       = {{Cordier, Fleur and Van der Meulen, Joni and Loontiens, Siebe and Van Roy, Nadine and Lapeire, Lore and Willaert, Wouter and Ferdinande, Liesbeth and Van de Vijver, Koen and Van Dorpe, Jo and Creytens, David}},
  issn         = {{0344-0338}},
  journal      = {{PATHOLOGY RESEARCH AND PRACTICE}},
  keywords     = {{Cell Biology,Pathology and Forensic Medicine,RNA-based next generation sequencing,High-grade endometrial stromal sarcoma,Undifferentiated sarcoma,Sarcoma with BCOR genetic alterations}},
  language     = {{eng}},
  pages        = {{6}},
  publisher    = {{Elsevier BV}},
  title        = {{High-grade endometrial stromal sarcoma-like sarcoma in male : does it exist? A case report and review of the literature}},
  url          = {{http://doi.org/10.1016/j.prp.2022.154228}},
  volume       = {{241}},
  year         = {{2023}},
}

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