Project: MICROPLASTICS AS A VECTOR OF PATHOGENS CONTAMINATION, INFECTION AND RESISTANCE: A CASE OF Campylobacter IN POULTRY PRODUCTION AND PROCESSING
2023-01-01 – 2025-12-31
- Abstract
Campylobacter are well adapted to life in the intestines of animals and humans, so it is surprising that they can also survive on the surface of meat and following the best cleaning used to remove organic matter from facilities and equipment. Researchers have recently solved this puzzle, showing the enormous benefit for Campylobacter from multispecies biofilm communities. We are aware of sites prone to biofilm formation, but we are not aware of the presence of microplastics in the environment of poultry processing. Such microplastics can enormously increase the attachment area for bacteria, and thus they can persist through the food production processes. The objective of the project is to understand the role of microplastics, as they provide an enormous surface area on which bacteria can attach, form biofilms, and potentially travel through the surrounding environments, each of which include the presence of variable microbial communities, food organic materials, and conditions such as the presence of antimicrobial drugs. Microplastics can promote the diversity of biofilm communities, which will vary while moving through the surrounding environment, with increased horizontal transfer of resistance genes between bacteria. The Project data will be original and will explain the importance of biofilm formation on microplastics, and the role of these microplastics in survival, persistence and virulence of the foodborne pathogen Campylobacter.
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Metabolic and structural impact of food iminosugars and synthetic derivatives in colon cancer cell lines
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- Journal Article
- A1
- open access
Role of microplastics in the survival and antimicrobial susceptibility of Campylobacter jejuni
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- Journal Article
- A1
- open access
Curcumin-based benzothiazepane analogues exhibit selective anti-cancer activity in HCT-116 cells via precipitated particle formation and internalisation
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Modulation of bioenergetics and cell growth in intestinal cancer lines by natural and synthetic iminosugars
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- Journal Article
- A1
- open access
Microplastics-assisted campylobacter persistence, virulence, and antimicrobial resistance in the food chain : an overview
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Natural and synthetic iminosugars reduce colorectal cancer cell viability and alter bioenergetic metabolism via specific mechanisms
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Evaluation of iminosugars’ glycomimetic and cytotoxicity effects on healthy and carcinogenic colorectal cells
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Iminosugar effects on (cancer) cell lines, and their biomanufacturing
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From genetic resources to bioprocess development : tools and technologies to help you create a robust microbial fermentation process
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Challenges for global food safety : top-down view