Project: MOlecular mechanisms of cellular DEath and Life decisions in Inflammation, Degeneration and Infection
2018-01-01 – 2021-12-31
- Abstract
The research program on Molecular mechanisms of cellular DEath and Life decisions in Inflammation, Degeneration and Infection (MODEL-IDI) aims at performing fundamental research on the biology of cell death modalities, cell survival regulation and their consequences on the onset and/or progression of diseases. The program aims at linking the discoveries obtained in vitro on the molecular regulation of cell death and inflammation to their in vivo physiological relevance by making use of chemical tool compounds and experimental models of diseases, such as diabetes type I & II, hepatotoxicity and liver cancer,
atherosclerosis and neurodegenerative diseases.
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- Journal Article
- A1
- open access
The thymus road to a T cell : migration, selection, and atrophy
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- Journal Article
- A1
- open access
Ferroptosis is a targetable detrimental factor in metabolic dysfunction-associated steatotic liver disease
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- Journal Article
- A1
- open access
Ferroptosis in health and disease
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- Journal Article
- A1
- open access
TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice
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- Journal Article
- A1
- open access
Need for standardization of Influenza A virus-induced cell death in vivo to improve consistency of inter-laboratory research findings
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- Journal Article
- A1
- open access
RIPK1 protects naive and regulatory T cells from TNFR1-induced apoptosis
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- Journal Article
- A1
- open access
Therapeutic exploitation of ferroptosis
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- Journal Article
- A1
- open access
Type 1 immunity enables neonatal thymic ILC1 production
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A guide to ferroptosis, the biological rust of cellular membranes
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- Journal Article
- A1
- open access
A guide to the expanding field of extracellular vesicles and their release in regulated cell death programs