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Project: Structural and functional research on human catenins in normal and malignant cell-types.

project duration
01-OCT-93 – 31-DEC-99
abstract
Our research aims at cDNA and genomic characterisation of the human AlfaN-/AlfaE-/Beta en Gamma catenins, which are linking proteins between the cadheriuis and the cytoskeleton. Further we will analyse their expression and functionality, with specialemphasis on their implication in the invasive and metastatic character of malignant tumorcells.