Project: Identification and characterization of protein factors at the level op the P55 TNF receptor, which are functional intermediates for the signal transduction pathways leading to gene activation
- project duration
- 01-OCT-94 – 31-DEC-99
- This study includes the preparation, in massive amounts of the entire p55 receptor molecule or of its intracellular domain, required for the isolation of associated proteins involved in signal transduction. the biochemical and functional characterization of these protein factors must lead to detection of the various, TNF mediated signal transduction pathways in the eukaryotic cell.