Project: Isolation and characterization of retention solutes, responsible for uremic immune suppression.
- project duration
- 01-JAN-99 – 31-DEC-01
- The aim of this study is to identify the mechanisms which are responsible for the currently found immune deficiency of uremia. Attention is focused on : 1) the identification of lipophilic compounds with immune suppressing effect 2) the kinetics of p-cresol, a known immune depressor 3) the compounds that change the immune modulating effect of the active vit D-analogue calcitriol.