Ghent University Academic Bibliography

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Project: The use of Xenopus embryos for studying the adhesive and signaling functions of cadherins and catenins.

project duration
01-JAN-01 – 31-DEC-03
abstract
We use transgenic frog embryos as a model system to study the involvement of cadherins/catenins in tumorigenesis. We focus on three aspects. (i) Identification of new target genes for B-catenin signaling. (ii) the involvement of cadherins/catenins in cellular processes implicated in tumorigenesis. (iii) Characterization of regulatory elements in the promoter regions of cadherins/catenins possibly related to tumorigenesis.