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Project: Analysis of alterations in gene expression and phenotypic characterization of ligand and cytokine activation of iNKT cells and comparison to autoimmune disease iNKT cells from RA and AS patients

01/09/13 – 31/08/15

Abstract
Analysis of the iNKT cells activated by direct or indirect stimulation using various ligands and cytokines will be compared by gene array and / or next generation sequencing, functional assays and cell surface marker expression. RA and AS patient iNKT cells will be analyzed to identify pathways altered in disease